Hiv-duo Test

The HIV duo test gets its name from the antigen and antibodies it detects. This test detects the anti-HIV 1, anti-HIV-2 total immunoglobulins, and HIV-1 p24 antigen. The p24 antigen are detectable as early as 28 days of sexual exposure. Hence HIV infection can be detected early, resulting in a better prognosis. These are also known as fourth-generation HIV tests.

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I had protected vaginal sex with a massage lady and all my HIV test results came negative. How much risk can I exclude?

Query: Hello doctor, I am a 26-year-old male. Two months back, I had unprotected oral sex and protected vaginal sex with a massage lady. 16 to 17 days later, I had a fourth-generation HIV test at the hospital, which came back negative. On days 37, 42, and 49, I used a rapid third-generation test at home, w...  Read Full »

Dr. Ravinder K. Manchanda

Answer: Hello, Welcome to I went through your query and understand your concern. 1. Although your HIV (human immunodeficiency virus) test results are quite assuring, you still need to undergo a confirmatory HIV rapid antibody test after three months of last exposure. There is no need to repeat...  Read Full »

Are stomach pain, headache and sweating in head after gay encounter symptoms of HIV?

Query: Hello doctor, I am a 32-year-old male. I had a gay encounter with four men in a massage parlor in three different days. In all the four cases we have used condoms but once the condom slipped. In my second and third encounter, I got a lot of blood and that too very dark color blood and something els...  Read Full »

Dr. Rakesh Kumar Bahunuthula

Answer: Hello, Welcome to HIV infection has a window period of one to three months during which the test results can be a false negative. Homosexual exposures have a higher risk of HIV transmission than other modes. According to WHO (world health organization), all test results of HIV are consi...  Read Full »

My HIV antibody and antigen tests are negative, days after having protected sex with a sex worker. Should I go for further testing?

Query: Hello doctor, I had a protected intercourse with a female sex worker. I tested negative for HIV ribonucleic acid polymerase chain reaction test, HIV 1 and 2 antibodies, and protein 24 antigen test. Do I need any further testing or is it conclusive? Please help.   Read Full »

Dr. Basti Bharatesh Devendra

Answer: Hello, Welcome to Thank you for your query. The chances of transmission of HIV (human immunodeficiency virus) by single protected intercourse is almost nil if the condom was used in a proper manner. The chances of HIV tests coming positive later is almost nil, with the given test res...  Read Full »

I had diarrhea, dry cough, sore throat, and fever after unprotected oral sex, and tested negative for HIV. Why?

Query: Hello doctor, I had unprotected oral sex with a guy, but he did not ejaculate. He penetrated me unprotected for about two minutes and then had put on a condom. After we were done, he removed the condom, cleaned himself, and penetrated again for about two minutes. I stopped him because he did not wea...  Read Full »

Dr. Kiran Anaparthi

Answer: Hi, Welcome to I understand your concern. The test for HIV (human immunodeficiency virus) is a fourth-generation dual test, a combined antigen and antibody test. The window period is the time during which the body responds to viruses and starts producing antibodies for defense, but de...  Read Full »

Is HIV test a fasting or non-fasting test?

Query: Dear doctor,Which is the primary blood test for HIV? Is it fasting or nonfasting? I want to get tested for a routine checkup.  Read Full »

Dr. Ravinder K. Manchanda

Answer: Hello, Welcome to The recommended primary test for HIV detection is the fourth generation HIV rapid test. You need not be fasting for this test. If there is a recent exposure and the test result comes negative, a confirmatory test needs to be done at three months of last exposure. Pleas...  Read Full »

My HbsAb is below 10 IU/ml. Do I need a booster shot for hepatitis B?

Query: Hi doctor, I was exposed to a needlestick injury around ten weeks ago, and I ran a series of tests out of fear. They are as follows: 1) HIV (human immunodeficiency virus) combination test - Non-reactive. 2) HbsAg (hepatitis B surface antigen) test - Non-reactive. 3) HCV (hepatitis C virus) test was ...  Read Full »

Dr. Shubadeep Debabrata Sinha

Answer: Hello, Welcome to I read your query and can understand your concern. The laboratory tests you took are negative for viral illnesses possibly transmitted by needle stick injury, primarily HIV (human immunodeficiency virus). However, it is a good idea to keep getting tested yearly. Ot...  Read Full »

Does the p24 antigen get detected after nine months of HIV infection without treatment?

Query: Hello doctor,I am concerned regarding p24 antigen detection. I read in different articles that it is delectable for only two months, and later it disappears as antibodies are formed. The antigen appears again if the person is not being treated. Is it like that? Does the p24 antigen level increase an...  Read Full »

Dr. Arun Kaushik. R

Answer: Hello, Welcome to The p24 antigen can be detected faster than antibodies. After two months, as one produces antibodies, the virus will be killed, and the p24 might not be detectable. However, once the antibody level reduces in the body, the antigen can be detected as the viral l...  Read Full »

What does non-reactive mean in HIV test?

Query: Hi doctor, I have allergies like sneezing, running nose, pain behind the eyes due to strong fragrance or dust, and taking homeopathy medicines. I used to have these allergies before a sexual incident, but they are getting worse after that. Also, when I think more about HIV, these allergies get wors...  Read Full »

Dr. Ravinder K. Manchanda

Answer: Hi, Welcome to The allergy details mentioned are non-specific. So, you have been identified with a specific allergen. Antiallergic homeopathic medicines are unlikely to interfere with the test result. I suggest you regularly do some breathing exercises for 15 to 20 minutes a day along...  Read Full »

What are the possible ways for HIV (human immunodeficiency virus) transmission?

Query: Hi doctor, Good day. I believe you would clarify my issue. I had protected sex with a sex worker. My condom did not break or slip during the intercourse. I hardly had three seconds of intercourse before my sperms came out. So, I put on my trousers with the condom on my penis and rushed to the bathr...  Read Full »

Dr. Ravinder K. Manchanda

Answer: Hi, Welcome to The answers to your queries are: If the condom had been used correctly and as you mentioned if there was no break or slipping off during the act, the risk of acquisition of HIV (human immunodeficiency virus) and other STIs (sexually transmitted infections) is non-exi...  Read Full »

Please suggest if the CMIA test for HIV is conclusive.

Query: Hi doctor, Please suggest how far is CMIA test for HIV is conclusive at six months. Some say that three months are sufficient enough and a few say that six months is conclusive for 98% cases. Which is the truth? Which is the category who take more than three months for seroconversion?  Read Full »

Dr. Mansuri Uzzaif Usmangani

Answer: Hi, Welcome to CMIA (chemiluminescent microparticle immunoassay) also know as HIV-DUO test. It checks for two things, both antigen and antibody. So, this test is highly conclusive after six weeks, and at six months, it is very conclusive. Seroconversion means developing antibody agains...  Read Full »

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