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Can HIV be ruled out after multiple negative test results?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 26-year-old male. Two months back, I had unprotected oral sex and protected vaginal sex with a massage lady. 16 to 17 days later, I had a fourth-generation HIV test at the hospital, which came back negative. On days 37, 42, and 49, I used a rapid third-generation test at home, which also showed negative results. On the 49th and 51st day, I used the Alere HIV combo test and received negative results. How much risk can I exclude?

Thank you.

Hello,

Welcome to icliniq.com.

I went through your query and understand your concern.

1. Although your HIV (human immunodeficiency virus) test results are quite assuring, you still need to undergo a confirmatory HIV rapid antibody test after three months of last exposure. There is no need to repeat the test in between.

2. Unprotected oral sex carries a negligible to low risk of the acquisition of HIV.

3. If the vaginal sex was protected, and a condom was used consistently and correctly, the risk of the acquisition of HIV through protected vaginal sexual contact is non-existent.

I hope this helps.

Thank you.

Medically reviewed byiCliniq medical review team

Published At May 30, 2023
Reviewed AtJune 19, 2025

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