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How effective is PrEP for HIV prevention?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My friend just moved to a big city and is proactive about his health. He is been hearing a lot about PrEP as a way to prevent HIV and is thinking about starting it.

Can you explain how PrEP works and how effective it is in preventing HIV transmission? Also, what does he need to know about the routine blood tests and potential side effects? He is not sure how to start the conversation with his doctor, so any advice would be great.

Thank you.

Answered by Dr. Sugandh Garg

Education:

MBBS

Professional Bio:

Dr. Sugandh Garg is a qualified medical professional with an MBBS degree and an MD in Forensic Medicine, with significant experience as a COVID-19 expert. Since March 2020, he has been actively working with the government civil hospital COVID team, managing emergency cases and overseeing quarantine and isolation protocols. He has played a key role in supporting COVID-19 patients through structured treatment guidance and diet protocols, contributing to effective patient care during the pandemic.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

PrEP (pre-exposure prophylaxis) is a highly effective medication when taken correctly, reducing the risk of HIV transmission by up to 99 percent from sexual contact and at least 74 percent from injection drug use.

PrEP works by maintaining a steady level of HIV-fighting medication in the body, so if your friend is exposed to the virus, the medication can stop it from establishing an infection.

Before starting PrEP, your friend will need to have an HIV test to confirm he is HIV-negative, as PrEP is only for people who do not have HIV. Regular blood tests will also be needed every three months to monitor kidney function and ensure there are no adverse effects.

A physical examination by a doctor to check for sexually transmitted infections (STIs) during follow-up visits. Common side effects include nausea, headaches, and mild stomach discomfort.

To start the conversation with his doctor, he can simply mention that he has been hearing about PrEP and wants to know if it is right for him based on his lifestyle and the potential risk of HIV exposure. Most healthcare providers are familiar with PrEP and can guide him.

Get well soon. Feel free to follow up with any questions.

I hope this helps.

Thank you, and take care.

Regards.

Medically reviewed by iCliniq medical review team
Published At December 4, 2024
Reviewed At December 10, 2025

Education:

MBBS

Professional Bio:

Dr. Sugandh Garg is a qualified medical professional with an MBBS degree and an MD in Forensic Medicine, with significant experience as a COVID-19 expert. Since March 2020, he has been actively working with the government civil hospital COVID team, managing emergency cases and overseeing quarantine and isolation protocols. He has played a key role in supporting COVID-19 patients through structured treatment guidance and diet protocols, contributing to effective patient care during the pandemic.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Sugandh Garg is a qualified medical professional with an MBBS degree and an MD in Forensic Medicine, with significant experience as a COVID-19 expert. Since March 2020, he has been actively working with the government civil hospital COVID team, managing emergency cases and overseeing quarantine and isolation protocols. He has played a key role in supporting COVID-19 patients through structured treatment guidance and diet protocols, contributing to effective patient care during the pandemic.

This doctor is not available for online consultations on the platform anymore.

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