HIV or human immunodeficiency virus is a virus that is sexually transmitted and affects the body's ability to fight infections. It is a lifelong condition that progresses to a more severe form known as AIDS in the long run.

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Will an HLA-B35/58 person produce antibodies against HIV?

Query: Hello doctor, I have studied that HLA-B35, HLA-B58, and HLA-B7 are responsible for the rapid progression of AIDS and often test false negative when tested. However, with C clade virus it is somewhat protective and does not lead to rapid disease progression which has something to do with the CD8 T ce...  Read Full »

Dr. Ravinder Kaur Sachdeva

Answer: Hello, Welcome to Yes, HLA-B35/58 (human leukocyte antigen) person will be able to produce antibodies against HIV-1 (human immunodeficiency virus). This is true for all clades. The immunogenic response is known to be somewhat greater in clade C due to a higher diversity of im...  Read Full »

What antibiotics are recommended for chlamydia in an HIV positive?

Query: Hi doctor, I tested positive for chlamydia IgA IgG. Negative IgM. I am HIV positive but undetectable viral load and CD4 724. Recommended antibiotic? Thanks.  Read Full »

Dr. Sushil Kakkar

Answer: Hello, Welcome to A high title of IgA and IgG antibodies to chlamydia generally indicates active infection but it is an auxiliary test and should also be supplemented by a more specific nucleic acid amplification test (NAAT) on a urine sample. A NAAT test specifically detects chlamydi...  Read Full »

I started post-exposure prophylaxis within 24 hours, and my fourth-generation HIV test was negative. Kindly help.and my fourth-generation HIV test was negative. Kindly help.

Query: Hello doctor,I had unprotected vaginal sex with a masseuse and started post-exposure prophylaxis with Viropil within 24 hours. On the 19th day of the post-exposure prophylaxis, I had vaginal sex with my girlfriend. The next day, I had a fourth-generation HIV test, and the result was negative. My HI...  Read Full »

Dr. Basti Bharatesh Devendra

Answer: Hello, Welcome to I read your query and understand your concern. The chances of transmission of HIV (human immunodeficiency virus) by a single unprotected intercourse is low. Post-exposure prophylaxis (PEP) initiated within 24 hours is a very good sign though not 100 percent protecti...  Read Full »

I am HIV infected and I have a white coating on the tongue. Please guide me.

Query: Hi doctor,I am a 28-year-old male. My height is 5 feet 9 inches and weight is 80 kg. I am HIV infected and I got red blisters on my tongue with a white coating on the tongue surface.  Read Full »

Dr. Rakesh Kumar Bahunuthula

Answer: Hello, Welcome to Your complaints are more in favor of oral candidiasis. This is an opportunistic infection in the immunosuppressed patients. Kindly mention your CD4 count, RNA (ribonucleic acid) load, and the medication that you are using. Please attach the appropriate images.   Read Full »

I touched a used needle.Is there any chance of me getting HIV infection?

Query: Hello doctor, I work for a company where there is one person who is a diabetic. He uses regular insulin injections. Well, I was not paying attention when I picked up the trash can because it fell over, and I touched a used needle. I know I did not get pricked because it did not pierce my skin. I als...  Read Full »

Dr. Sushil Kakkar

Answer: Hi, Welcome to The risk of infection from needlestick injuries depends on: The factors that influence exposure to a greater volume of blood (for example: visible blood on the device, needle which has been placed directly into an artery or a vein of an HIV positive person). Viral...  Read Full »

The girl used her spit for lubrication. Can I be HIV positive?

Query: Hello doctor,My question is regarding possible HIV exposure six weeks ago. The condom protected vaginal and oral although she did masturbate me without a condom and used spit for lubrication. I took the fourth generation ELISA at four weeks and five weeks and both were negative. I was on a testoster...  Read Full »

Dr. Jeremy David O' Kennedy

Answer: Hello, Welcome to I am pleased to help you with your concern. The risk of transmission of the HIV (human immunodeficiency virus) in the scenario you have described is extremely low, even if your sexual partner was an infected carrier. There is very little evidence to support a high t...  Read Full »

HIV 1 and 2 are nonreactive 28 days after exposure. Should I repeat it later?

Query: Hello doctor, HIV 1 and 2 are nonreactive in the tri-dot test done after 28 days of exposure. Should I repeat the test for confirmation?  Read Full »

Dr. Rakesh Kumar Bahunuthula

Answer: Hello, Welcome to Tri-dot is a third-generation test for HIV (human immunodeficiency virus). HIV infection has a window period of one to three months, during which these test results may be false negative. According to WHO (world health organization), all the test results are conside...  Read Full »

Is there a new medicine for 100 % cure of HIV?

Query: Hello doctor,My brother was detected as HIV positive. Is this disease completely curable or not? Is there any new medicine for a 100 % cure for this disease?  Read Full »

Dr. Ravinder Kaur Sachdeva

Answer: Hello, Welcome to There is so effective a treatment available for HIV (human immunodeficiency virus) that it is no longer a dreadful disease. Antiretroviral treatment (ART) needs to be taken regularly with 100 % adherence. With regular ART, HIV will be completely suppressed, and th...  Read Full »

After having unprotected intercourse with a CSW seven months ago, I am experiencing swollen lymph nodes in my neck and a sore throat. Why?

Query: Hello doctor, I had unprotected exposure 7 months ago with a commercial sex worker, and I do not know her HIV status. Since then, I have had multiple fourth-generation tests and a PCR test for HIV. My fourth-generation HIV test has been negative till now. But I have had a swollen lymph node in my ne...  Read Full »

Dr. Sushil Kakkar

Answer: Hello, Welcome to Your tests for sexually transmitted diseases (including HIV) are conclusive. A 4th generation HIV (human immunodeficiency virus) screening test is considered conclusive at six weeks from risk exposure. Most other STDs would also be detectable by laboratory tests by s...  Read Full »

Will low neutrophil count be the cause for low-grade fever and joint pain?

Query: Hello doctor, I am a 24-year-old female. I have done my blood work and the neutrophil count is very low 0.6 from normal in a matter of weeks and I do not understand why. Other symptoms, I am having are low-grade fever, joint pain (knees, hips, and shoulders), extreme fatigue, and spasms in my leg. ...  Read Full »

Dr. Vandana Andrews

Answer: Hi, Welcome to Your concerns are valid. The symptoms could be due to a condition called neutropenia (low neutrophil counts). It is generally seen in conditions like infections viral, bacterial, or parasitic infections. Examples include HIV (human immunodeficiency virus), tuberculosis...  Read Full »

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