Can stem cell transplant help treat relapsed tumors in Hodgkin's lymphoma?

Question

Hello doctor,

I am a 52-year-old male, and I was diagnosed with Hodgkin's lymphoma a year ago. To date, I have undergone ten cycles of ABVD (Adriamycin, Bleomycin, Vinblastine, and Dacarbazine), but they have not fully removed the tumor. The tumor relapsed again. The doctor advised doing the autologous stem cell transplantation.

What should I do?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

I have read the query, and I can understand your concern.

The choice of treatment prescribed for individual patients with relapse depends on several factors, including the histopathological details, IHC (immunohistochemistry), molecular profile, the timing of the relapse, age, overall health of the patient, scope of the disease, and previous therapies received.

The current standard for secondary treatment in most patients consists of combination therapy, usually followed by autologous stem cell transplantation. There is also a variety of single-agent and combination therapy regimens that may be used for relapsed or refractory Hodgkin’s lymphoma, including:

Brentuximab vedotin.
Bendamustine.
Nivolumab.
Pembrolizumab.
DHAP (Dexamethasone, Cisplatin, and Cytarabine).
ESHAP (Etoposide, Methylprednisolone, Cisplatin, and Cytarabine).
GVD (Gemcitabine, Vinorelbine, and Liposomal doxorubicin)
ICE (Ifosfamide, Carboplatin, and Etoposide).
IGEV (Ifosfamide, Gemcitabine, and Vinorelbine).

I hope this will help you.

Thank you.