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HomeAnswersMedical oncologyhodgkin's lymphomaI have a relapsed HL tumor despite treatment. Why?

Can stem cell transplant help treat relapsed tumors in Hodgkin's lymphoma?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At March 30, 2024
Reviewed AtMarch 30, 2024

Patient's Query

Hello doctor,

I am a 52-year-old male, and I was diagnosed with Hodgkin's lymphoma a year back. To date, I have undergone ten cycles of ABVD (Adriamycin, Bleomycin, Vinblastine, and Dacarbazine), but they did not fully remove the tumor. The tumor relapsed again. The doctor advised to do the autologous stem cell transmission. What should I do? Please help.

Thank you.

Hello,

Welcome to icliniq.com.

I have read the query, and I can understand your concern.

The choice of treatment prescribed for individual patients with relapse depends on several factors, including the histopathological details, IHC (immunohistochemistry), molecular profile, the timing of the relapse, age, and overall health of the patient, scope of the disease, and previous therapies received. The current standard for secondary treatment in most patients consists of combination therapy, usually followed by autologous stem cell transplantation. There is also a variety of single-agent and combination therapy regimens that may be used for relapsed or refractory Hodgkin’s lymphoma, including:

  1. Brentuximab vedotin.

  2. Bendamustine.

  3. Nivolumab.

  4. Pembrolizumab.

  5. DHAP (Dexamethasone, Cisplatin, and Cytarabine).

  6. ESHAP (Etoposide, Methylprednisolone, Cisplatin, and Cytarabine).

  7. GVD (Gemcitabine, Vinorelbine, and Liposomal doxorubicin)

  8. ICE (Ifosfamide, Carboplatin, and Etoposide).

  9. IGEV (Ifosfamide, Gemcitabine, and Vinorelbine).

I hope this will help you.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Arshad Hussain Shah
Dr. Arshad Hussain Shah

Medical oncology

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