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HomeAnswersEndocrinologyhyperthyroidismI take 150 mcg Thyroxine and feel tired. Will dose reduction meet the cause?

Increased dose for hyperthyroidism end up causing hypothyroidism. What to do?


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Shaikh Sadaf

Medically reviewed by

Dr. Vinodhini J.

Published At March 18, 2020
Reviewed AtJune 7, 2023

Patient's Query

Hello doctor,

I am a 52-year-old female. I have an underactive thyroid condition. I had nuclear medicine a few years ago and had been going for regular checkups but recently due to some reasons, my TSH level had increased. So I was given a dosage of 150 mcg of Thyronorm. My check-up was due four months but due to some circumstances I could not go and I went two months late. The doctor told me I had an overdose of it. So he asked me to continue only with 100 mcg. I was wondering if I would feel better if I skip the medicines for two days because it is making me feel tired a lot and weak, too.

Answered by Dr. Shaikh Sadaf


Welcome to icliniq.com.

I just read your query and from what you mentioned it appears you had hyperthyroidism which was treated with radioactive iodine and now you are hypothyroid. Well, it is perfectly normal phenomena, after radioactive iodine ablation of the thyroid gland we usually expect patients to be hypothyroid. In your case, it just took so long to develop. You should have gotten your thyroid function test done at that time but nonetheless your dose has been reduced so it is perfectly fine. You feel tired because of the excess 50 mcg which you had been taking until now. Anyways give it some time and it will settle down. No, it is not going to be dangerous. Just regularly do your thyroid function test every three months until it stabilizes.

I hope this helps.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Shaikh Sadaf
Dr. Shaikh Sadaf


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