Is it possible to start or continue chemotherapy at very low WBC counts?

Hello,

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Your child is having B-cell acute lymphoblastic leukemia. In that case, to induce remission, induction chemotherapy should be given to restore normal bone marrow. After induction, maintenance chemotherapy also to be given. Your total count might be low because of chemotherapy but your daughter was having 87 % blast so chemotherapy should be given.

You can investigate further with a molecular study of different translocation which reflects prognosis in case of ALL (acute lymphoblastic leukemia). So consult your hemato-oncologist for examination and under the guidance of the oncologist, chemotherapy should be given. Take care.

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You are going through a very tough situation for your daughter. Your daughter is having very low WBC count and it is called severe neutropenia. But the decision has to be individualized after clinical correlation. The induction chemotherapy can be completed under strict doctor observation. In neutropenia chance of infection is present. So if any unusual bleeding, prolonged vomiting, fever, etc., occur then infection should be ruled out.

Meanwhile, care can be taken in form of providing nutritious foods like green leafy vegetables and fruits and hand washing should be encouraged. So, if possible and no infection present then chemotherapy can be continued as per my opinion. WBC transfusion can be given to raise neutrophils count but that has to be discussed with your treating doctor and as per need after clinical correlation. Take care.

Hello,

Welcome back to icliniq.com.

You are welcome.