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I have lung nodules. Is it due to endometrial cancer recurrence?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have lung nodules with a history of endometrial cancer (FIGO stage 2) 10 years ago. There is a slight increase and a slight decrease in the size of lung nodules in the span of three months. My CT biopsy, which was done three months ago, was inconclusive.

Please help.

Answered by Dr. Ali Osman

Education:

MBBS

Professional Bio:

Dr. Ali Osman is a dedicated obstetrics and gynecology specialist committed to providing compassionate and comprehensive care for women at every stage of life. He has experience in managing a wide range of women’s health concerns, including pregnancy care, menstrual disorders, reproductive health, and gynecological conditions. Dr. Osman focuses on patient education, preventive care, and personalized treatment plans to ensure the best possible outcomes. Known for his supportive and professional approach, he strives to create a comfortable environment where patients feel heard, respected, and confident in their healthcare journey.      

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to iCliniq.com.

I understand your concern.

According to my understanding, the most likely considerations in this situation include:

  1. Metastatic recurrence of prior endometrial cancer.
  2. Primary lung nodules unrelated to the previous malignancy.
  3. Benign inflammatory or infectious nodules.
  4. Scar tissue or granulomatous disease.

Your history of FIGO (International Federation of Gynecology and Obstetrics) stage II endometrial cancer increases concern for possible late metastasis, even after ten years, although late recurrence is less common.

Pulmonary nodules that exhibit slight changes in size within a three-month period may be indicative of inflammation or infection rather than metastasis since the latter normally exhibits progressive growth characteristics.

If the diagnosis is described as "indeterminate CT-guided biopsy," then the tissue sample has not been able to show whether the pathology is malignant or benign. This may be due to the small size of the lesion or due to inadequate tissue sampling.

This is followed by further imaging, PET-CT, or repeat biopsy, possibly utilizing a new modality for biopsy, such as navigational bronchoscopy or surgical biopsy.

A definitive diagnosis cannot be established without adequate tissue confirmation.

Current working diagnosis is indeterminate pulmonary nodules in a patient with prior endometrial carcinoma; rule out metastatic disease.

I hope this helps.

For more queries, feel free to reach out to me anytime. I am here to help you.

Thank you.

Answered by Dr. Ali Osman
Medically reviewed by iCliniq medical review team
Published At May 19, 2026
Reviewed At July 17, 2026

Education:

MBBS

Professional Bio:

Dr. Ali Osman is a dedicated obstetrics and gynecology specialist committed to providing compassionate and comprehensive care for women at every stage of life. He has experience in managing a wide range of women’s health concerns, including pregnancy care, menstrual disorders, reproductive health, and gynecological conditions. Dr. Osman focuses on patient education, preventive care, and personalized treatment plans to ensure the best possible outcomes. Known for his supportive and professional approach, he strives to create a comfortable environment where patients feel heard, respected, and confident in their healthcare journey.      

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Ali Osman is a dedicated obstetrics and gynecology specialist committed to providing compassionate and comprehensive care for women at every stage of life. He has experience in managing a wide range of women’s health concerns, including pregnancy care, menstrual disorders, reproductive health, and gynecological conditions. Dr. Osman focuses on patient education, preventive care, and personalized treatment plans to ensure the best possible outcomes. Known for his supportive and professional approach, he strives to create a comfortable environment where patients feel heard, respected, and confident in their healthcare journey.      

This doctor is not available for online consultations on the platform anymore.

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