Mean Platelet Volume

Mean platelet volume is one of the components in complete blood count. A normal MPV ranges between 9 fl to 12 fl. High MPV indicates increased production of the platelets. An increase in MPV alone cannot lead to any diagnosis. They must be correlated with other components of complete blood count and other investigations for a definite diagnosis. MPV can be increased in heart diseases, hyperthyroidism, diabetes, hypertension, vitamin D deficiency, cancer, thrombocytopenic purpura, myeloproliferative diseases, etc. Low MPV indicates Crohn's disease, aplastic anemia, etc.

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Are there abnormalities in my blood reports?

Query: Hello doctor,I got a blood test done this week. The investigations are as follows: Red cell distribution width is 11.4 %, platelets count is 130 thou/UI, mean platelet volume is 13.3 fL. Morphology remarks: Gaint platelets are seen, and small clumps of platelets are seen.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to Let me tell you that there are abnormalities like high MPV (mean platelet volume) and the presence of giant platelets. This type of picture occurs when there is platelet destruction. So, the bone marrow is stimulated more and hence a lot of premature platelets get ...  Read Full »

What causes low MPV in blood?

Query: Hello doctor, I looked at my CBC report for pre-operative clearance and my MPV is low (8.3). All other CBC values were normal. Should I be concerned?  Read Full »

Dr. Settipalli Saravan Pramod

Answer: Hi, Welcome to I just gone through all your blood reports. Everything seems to be normal (attachment removed to protect patient identity). MPV (mean platelet value) which you specially mentioned like to have on a low level than normal. For that, you initially like to know MPV help...  Read Full »

Does high mean platelet volume indicate a type of blood cancer?

Query: Hello doctor, I just had my routine medical check-up. And I got my CBC report. My platelet count is 210000 and in range but my MPV (mean platelet volume) is 12.8. Is it anything to really worry about?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to You need not to worry about your platelet count and MPV. In your attached report, total WBC (white blood cells) count is borderline low and lymphocyte count is borderline high. So it could be a temporary viral infection. You can repeat your CBC (complete blood count...  Read Full »

What causes high MPV?

Query: Hello doctor, My father is 65 years old. Recently, we went for his routine cardio checkup. His doctor suggested thallium stress test, which was normal. He has been hypertensive for 15 years and is on anti-hypertensive Ramipril 5 mg, Amlodipine 2.5 mg and one diuretic. His BP was high, so the doctor...  Read Full »

Dr. Naresh Kumar Monigari

Answer: Hello, Welcome to I had gone through all the reports posted (attachment removed to protect patient identity). Mean platelet volume suggests the mean volume of single platelet, which is high and is mostly an incidental finding. Some bleeding disorders like functional defects of platelets...  Read Full »

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