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Is high mean platelet volume of 12.8 something to worry about?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At March 26, 2020
Reviewed AtJune 6, 2023

Patient's Query

Hello doctor,

I just had my routine medical check-up. And I got my CBC report. My platelet count is 210000 and in range but my MPV (mean platelet volume) is 12.8. Is it anything to really worry about?

Hello,

Welcome to icliniq.com.

You need not to worry about your platelet count and MPV. In your attached report, total WBC (white blood cells) count is borderline low and lymphocyte count is borderline high. So it could be a temporary viral infection. You can repeat your CBC (complete blood count) after a few days to check the count again. Do not worry and repeat CBC after a few days. You can revert back once you repeat CBC.

Thank you.

Patient's Query

Hello doctor,

Actually, I got a little viral around the first week of two months ago and I recovered now. But my platelet count is 210000, which is in the range as its range is 150000 to 400000. But my mean platelet volume is 12.8 FL. Also, I checked my older reports and it was always between 11 to 12 FL I mean on the higher side.

I read on the internet that high MPV and low platelet count is a sign of some sought of chronic myelogenous leukemia cancer (CML) and I got worried. I just wanted to clarify that I hope I do not need to go for any getting of CML so I do not feel any symptoms.

Is it normal to have an MPV of 12.8? Is it really high or marginally high?

Hi,

Welcome back to icliniq.com.

Your MPV is marginally high. The borderline elevation does not suggest any blood cancer. In CML like blood cancer, total WBC count is usually very high like more than one lakh. Additionally, in CML differential count shows elevation of basophils. So your attached report does not suggest blood cancer. Do not worry. (attachment removed to protect patient identity).

Thank you.

Patient's Query

Hello doctor,

I think my white blood cells and basophils are on the lower side and in all reports they are normal like 4200 to 5000.

Secondly what can cause high MPV? Can it be just natural for them to be high? Should I not worry at all about MPV and cancer?

Hi,

Welcome back to icliniq.com.

The MPV reflect the size of platelet. It can be high when platelet destruction present in the blood. Viral Infection also could be responsible. You need not worry about MPV. Do not worry about that.

In blood cancer like leukemia total count high and immature granulocyte present like basophils, myelocytes, metamyelocytes, etc. which is not present in your case. So leukemia chance is almost nil. You might need not to worry about that.

Thank you.

Patient's Query

Thank you doctor,

So according to the attached report changes are almost nil or totally nil? Also is TLC count low? Does it suggest viral infection or bacterial? Can it be due to any recent viral infection?

I had a little cough and sneezing but no fever around 10th March but now I am totally fine.

Hello,

Welcome back to icliniq.com.

You need not worry about the attached CBC report. (attachment removed to protect patient identity).

The viral infection seems most likely in your case. You need to repeat CBC after a few days. Drink more water. The attached report does not suggest leukemia or any blood cancer.

Thank you.

Patient's Query

Thank you doctor,

Since my TLC count is low, should I be more worried about getting infected by COVID-19? Is my immunity low as TLC count is just 3800? Should I take vitamin C and I am anyways at home and do not go out at all?

Hello,

Welcome back to icliniq.com.

The borderline low level does not suggest weak immunity. COVID-19 can infect an individual with adequate immunity as well. So you are doing the right way of not going outside the home. If you are going to the hospital area then wear a mask. Do frequent hand washing with soap and water. Use sanitizer as well.

Vitamin C does not prevent COVID-19 infection. However, it can boost your immunity. You can take it or you can take more fruit rather than tablets.

Thank you.

Patient's Query

Hello doctor,

Today I checked my temperature and I have a 98.8 to 99 fever in my mouth but under my arm, it is 96.5. As such I do not have any cough, cold, or bad throat. I just had back pain for a few days and was taking Voveron for that. Is a 99-degree Fahrenheit fever in the mouth cause of concern?

Hello,

Welcome back to icliniq.com.

Following is my opinion about your asked question. A body temperature of more than 98.6 F is called a fever. The temperature is usually taken in the axillary area. So keep a thermometer in the axillary region and measure the temperature. If your axillary temperature is more than 98.6 F continuously then you can take over-the-counter antipyretics and consult a doctor. In COVID 19 infection usually along with fever, weakness, cough, or cold is present. So it does not look like COVID. However, if you have a continuous fever then it is better to consult your doctor. I hope I have answered your question

Let me know if I can assist you further.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

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