HomeAnswersNeurologymigraine

How do I manage migraines when injections stop working?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been getting migraines since my late 30s, and for a good 8 years, the monthly injections were basically a lifesaver for me. However, for the past six or seven months, they just are not working the same way anymore. I am still getting three to four bad migraines a month, even with the injections.

How does a 58-year-old manage migraines after years on injectable treatment that worked when suddenly it does not, and you are kind of back to square one again?

Kindly help.

Answered by Dr. Ashraf Ghani

Education:

MD

Professional Bio:

Dr. Ashraf Ghani Niazai is a GMC-certified General Medicine Specialist, recognized by the prestigious General Medical Council (UK). With extensive experience in diagnosing and managing a wide range of acute and chronic health conditions, he combines advanced medical knowledge with genuine compassion for his patients. He is skilled in internal medicine, obstetrics and gynecology, dermatology, preventive healthcare, and lifestyle management, always focusing on personalized, evidence based care to achieve the best possible outcomes. As an inspiring medical educator, he has taught thousands of medical students and contributed multiple research publications to the field of medicine, reflecting his commitment not only to treating patients but also to advancing medical science. Patients value his warm approach, clear communication, and dedication to their long term health and well being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

I can understand why this feels so discouraging. When a treatment has given you years of good control, having migraines return can make it seem as though you are back where you started.

The good news is that you are not out of options. It is worth seeing your neurologist or headache specialist because a change in your migraine pattern after years of stability often calls for a reassessment. They may look for factors such as medication overuse from frequent pain relievers, changes in sleep, stress, hormone levels, new medical conditions, or other triggers that could be reducing the effectiveness of your current treatment.

Sometimes better control can be achieved by changing to another drug within the same class, changing to another preventive treatment, or by combining therapies. There are also newer migraine treatments for prevention and treatment of acute migraine attacks that might be appropriate if your current injections are not giving you enough benefit.

In the meantime, maintaining regular sleep, staying well hydrated, eating consistent meals, exercising as tolerated, and keeping a headache diary to track attacks and possible triggers can provide valuable information for your doctor.

Because you are 58, if these headaches are significantly different from your previous migraines, become suddenly severe, or are associated with weakness, vision loss, confusion, difficulty speaking, or other new neurological symptoms, you should seek urgent medical evaluation right away.

Even though this setback is frustrating, many people are able to regain good migraine control after adjusting their treatment plan, so there is good reason to be hopeful.

I hope you are satisfied with my answer. For further queries, you can consult me at iCliniq.

Thank you.

Medically reviewed by iCliniq medical review team
Published At July 9, 2026
Reviewed At July 13, 2026

Education:

MD

Professional Bio:

Dr. Ashraf Ghani Niazai is a GMC-certified General Medicine Specialist, recognized by the prestigious General Medical Council (UK). With extensive experience in diagnosing and managing a wide range of acute and chronic health conditions, he combines advanced medical knowledge with genuine compassion for his patients. He is skilled in internal medicine, obstetrics and gynecology, dermatology, preventive healthcare, and lifestyle management, always focusing on personalized, evidence based care to achieve the best possible outcomes. As an inspiring medical educator, he has taught thousands of medical students and contributed multiple research publications to the field of medicine, reflecting his commitment not only to treating patients but also to advancing medical science. Patients value his warm approach, clear communication, and dedication to their long term health and well being.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Ashraf Ghani Niazai is a GMC-certified General Medicine Specialist, recognized by the prestigious General Medical Council (UK). With extensive experience in diagnosing and managing a wide range of acute and chronic health conditions, he combines advanced medical knowledge with genuine compassion for his patients. He is skilled in internal medicine, obstetrics and gynecology, dermatology, preventive healthcare, and lifestyle management, always focusing on personalized, evidence based care to achieve the best possible outcomes. As an inspiring medical educator, he has taught thousands of medical students and contributed multiple research publications to the field of medicine, reflecting his commitment not only to treating patients but also to advancing medical science. Patients value his warm approach, clear communication, and dedication to their long term health and well being.

This doctor is not available for online consultations on the platform anymore.

Listen to related tracks in our music library
Comprehensive Second Opinion

Read answers about:

migraineheadachevision losssleep

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.