Common "Obstetric Cholestasis" queries answered by top doctors | iCliniq

Obstetric Cholestasis

Obstetric cholestasis is a liver condition that occurs in the second or third trimester of pregnancy. Here the liver cannot excrete bile properly. The symptoms include intense itching in the palms and feet, dark urine, light-colored stools, and jaundice.

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How can itching be effectively and safely controlled during pregnancy?

Query: Hello doctor, My wife is 35 years old and is four months pregnant now. She is suffering from severe itching which is not responding to any medication. Her doctor advised to take Udiliv 150 and Cetirizine, but there is no relief. We changed the doctor, and this doc advised to take Udiplus 300, capsul...  Read Full »


Dr. Neha Rathod

Answer: Hi, Welcome to icliniq.com. I have gone through your query and reports (attachment removed to protect patient identity). Yes, it is obstetric cholestasis. During pregnancy, Udiliv (Ursodeoxycholic acid) 300 mg is the best and effective treatment for cholestasis. Your gynecologist has prescribed yo...  Read Full »

How to treat severe body itching during pregnancy?

Query: Hi doctor, I am currently 26 weeks pregnant. I have developed severe itching all over my body, particularly in palms and soles of feet. I initially did not take it serious and kept applying coconut oil, Lacto calamine, etc., to get some relief. However, I did not get any relief from any of these. Th...  Read Full »


Dr. Megha Tuli

Answer: Hi, Welcome to icliniq.com. You have raised liver enzymes. This indicates that you have a condition called obstetric cholestasis (bile acid accumulation in blood resulting in constant itching during third trimester of pregnancy). It needs proper treatment and you need to get LFT - liver function t...  Read Full »

What causes the entire body to itch during pregnancy?

Query: Hi doctor, I am pregnant, and my entire body is itching. What could be the reason? Please help.  Read Full »


Dr. Gowrimeena

Answer: Hello, Welcome to icliniq.com. If there is itching alone (especially involving palms and soles) without any skin rashes, it could be a condition called obstetric cholestasis. In obstetric cholestasis, the liver is unable to send out the waste product called bile acids, and they accumulate in the blo...  Read Full »

My pregnant wife has vaginal itching. Can she take Udiliv?

Query: Hi doctor, My wife is in her 7th month of pregnancy. Since last 15 to 20 days, she has been experiencing itching throughout her body. She was ordered liver function test. Report for blood sample collected and attached. Based on this report, she has been taking Udiliv 150 mg twice a day and also Liv ...  Read Full »


Dr. Sameer Kumar

Answer: Hello, Welcome to icliniq.com. She is suffering from IHCP or intrahepatic cholestasis of pregnancy (attachment removed to protect patient identity) and hence the itching. The parameters have deranged and AST (aspartate aminotransferase), ALT (alanine aminotransferase) and Alkaline phosphatase have...  Read Full »

Can Atarax be taken for itching during pregnancy?

Query: Hello doctor,I am 8 months and 10 days pregnant. I am having itching in my whole body from the last eight days. I also tried Aloe Vera lotion for it. Is taking Atarax tablets safe for me at this time?  Read Full »


Dr. Nadia Khan

Answer: Hello, Welcome to icliniq.com. Do you have itching with rash or without rash? And do you have itching palms and soles as well? You may have obstetric cholestasis and you must see your obstetrician immediately and do not self treat the condition. You need liver function tests. Get checked to see if...  Read Full »

Is it normal for a 37 weeks pregnant lady to have itchy belly and hands?

Query: Hello doctor, My wife is 37 weeks pregnant. She has itching on her belly, hands, and feet. I read on the internet that, it may be PUPPP or cholestasis or neither both of them. Is it something to worry?  Read Full »


Dr. Gowrimeena

Answer: Hi, Welcome to icliniq.com. If the itching is present with rashes, it can be PUPPP (Pruritic Urticarial Papules and Plaques of Pregnancy). But you need to see a gynecologist or a dermatologist before we can come to a conclusion. Itching alone without any skin rashes can be cholestasis in pregnancy...  Read Full »

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