Obstetric Cholestasis

Obstetric cholestasis is a liver condition that occurs in the second or third trimester of pregnancy. Here the liver cannot excrete bile properly. The symptoms include intense itching in the palms and feet, dark urine, light-colored stools, and jaundice.

Recently Answered Questions Recently Answered Questions

Is it normal for a 37 weeks pregnant lady to have itchy belly and hands?

Query: Hello doctor, My wife is 37 weeks pregnant. She has itching on her belly, hands, and feet. I read on the internet that, it may be PUPPP or cholestasis or neither both of them. Is it something to worry?  Read Full »


Dr. Gowrimeena

Obstetrician And Gynaecologist

Answer: Hi, Welcome to icliniq.com. If the itching is present with rashes, it can be PUPPP (Pruritic Urticarial Papules and Plaques of Pregnancy). But you need to see a gynecologist or a dermatologist before we can come to a conclusion. Itching alone without any skin rashes can be cholestasis in pregnancy...  Read Full »

Can Atarax be taken for itching during pregnancy?

Query: Hello doctor,I am 8 months and 10 days pregnant. I am having itching in my whole body from the last eight days. I also tried Aloe Vera lotion for it. Is taking Atarax tablets safe for me at this time?  Read Full »


Dr. Nadia Khan

Obstetrician And Gynaecologist

Answer: Hello, Welcome to icliniq.com. Do you have itching with rash or without rash? And do you have itching palms and soles as well? You may have obstetric cholestasis and you must see your obstetrician immediately and do not self treat the condition. You need liver function tests. Get checked to see if...  Read Full »

What causes the entire body to itch during pregnancy?

Query: Hi doctor, I am pregnant, and my entire body is itching. What could be the reason? Please help.  Read Full »


Dr. Gowrimeena

Obstetrician And Gynaecologist

Answer: Hello, Welcome to icliniq.com. If there is itching alone (especially involving palms and soles) without any skin rashes, it could be a condition called obstetric cholestasis. In obstetric cholestasis, the liver is unable to send out the waste product called bile acids, and they accumulate in the b...  Read Full »

Is it safe to take Udiliv during pregnancy?

Query: Hi doctor, My wife is in her 7th month of pregnancy. Since last 15 to 20 days, she has been experiencing itching throughout her body. She was ordered liver function test. Report for blood sample collected and attached. Based on this report, she has been taking Udiliv 150 mg twice a day and also Li...  Read Full »


Dr. Sameer Kumar

Family Physician, Obstetrician And Gynaecologist, Infertility Specialist

Answer: Hello, Welcome to icliniq.com. She is suffering from IHCP or intrahepatic cholestasis of pregnancy (attachment removed to protect patient identity) and hence the itching. The parameters have deranged and AST (aspartate aminotransferase), ALT (alanine aminotransferase) and Alkaline phosphatase hav...  Read Full »

I am 35 weeks pregnant, can cholestasis be causing an itch on my stretch marks, arms, and thighs?

Query: Hi doctor, I am 35 weeks pregnant. By last week my stretch marks were started to itch. So, my OG advised applying Calamine lotion (which does not contain antihistamine). It seemed to soothe the itching, but slowly the itching started spreading to my upper arms and thighs. Then she prescribed Avil t...  Read Full »


Dr. R Balakrishnan Menon

Infertility Specialist, Obstetrician And Gynaecologist

Answer: Hi, Welcome to icliniq.com. I have gone through your reports (attachment removed to protect patient identity). Let me start by putting you at ease by saying that you are normal and your doctor has been doing a great job. As you are near delivery, the skin stretches to its maximum and the tissue u...  Read Full »

I am pregnant and having severe body itching. What is the treatment?

Query: Hi doctor, I am currently 26 weeks pregnant. I have developed severe itching all over my body, particularly in palms and soles of feet. I initially did not take it serious and kept applying coconut oil, Lacto calamine, etc., to get some relief. However, I did not get any relief from any of these. Th...  Read Full »


Dr. Megha Tuli Gupta

Obstetrician And Gynaecologist

Answer: Hi, Welcome to icliniq.com. You have raised liver enzymes. This indicates that you have a condition called obstetric cholestasis (bile acid accumulation in blood resulting in constant ithcing during third trimester of pregnancy). It needs proper treatment and you need to get LFT - liver functio...  Read Full »

How can itching be effectively and safely controlled during pregnancy?

Query: Hello doctor, My wife is 35 years old and is four months pregnant now. She is suffering from severe itching which is not responding to any medication. Her doctor advised to take Udiliv 150 and Cetirizine, but there is no relief. We changed the doctor, and this doc advised to take Udiplus 300, capsu...  Read Full »


Dr. Neha Singh Rathod

Obstetrician And Gynaecologist

Answer: Hi, Welcome to icliniq.com. I have gone through your query and reports (attachment removed to protect patient identity). Yes, it is obstetric cholestasis. During pregnancy, Udiliv (Ursodeoxycholic acid) 300 mg is the best and effective treatment for cholestasis. Your gynecologist has prescribed yo...  Read Full »

Why has itchiness come back in an obstetric cholestasis patient?

Query: Hello doctor,I was diagnosed with obstetric cholestasis two months back due to symptoms of itchy palms and feet. My LFT's and bile acids where raised. I was put on Ursodeoxycholic acid 500 gm twice daily and pregnancy vitamins. My symptoms disappeared within a week. I am closely monitored, weekly bl...  Read Full »


Dr. Uzma Arqam

Obstetrician And Gynaecologist

Answer: Hi, Welcome to icliniq.com. You are right. You have symptoms and signs of OC (obstetric cholestasis) that shows itching on palms and soles in the absence of rash with abnormal LFT and bile acid and resolves after birth. Obstetric cholestasis has increased the risk of preterm birth especially iatro...  Read Full »

What precautions to take for obstetric cholestasis?

Query: Hi doctor,My wife is in the second trimester and she has been detected with obstetric cholestasis. We have been recommended Udiliv. Everyone here seems to have this by the end of her pregnancy, but she got it early. What can we be doing to get everything under control?  Read Full »


Dr. Ravinder Kaur Khurana Kaur Khurana

Family Physician, Obstetrician And Gynaecologist

Answer: Hello, Welcome to icliniq.com. For cholestasis of pregnancy, the serum bile acid test and LFT (liver function test) are to be done once weekly or fortnightly depending on the severity. You should consult a liver specialist or gastroenterologist. This condition might affect the growth and liquor ...  Read Full »

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