Is it safe to take Udiliv during pregnancy?

Question

Hi doctor,

My wife is in her 7th month of pregnancy. Since last 15 to 20 days, she has been experiencing itching throughout her body. She was ordered liver function test. Report for blood sample collected and attached. Based on this report, she has been taking Udiliv 150 mg twice a day and also Liv 52 tonic twice a day for the past 10 days. Her LFT was repeated and the report for the same has also been attached here. Still parameters are out of range. Please suggest what should be done based on these two reports? Should she continue taking Udiliv 150 mg twice a day? Itching is still persisting, especially during the night. Is it something alarming?

Answer 1

Hello,

Welcome to icliniq.com.

She is suffering from IHCP or intrahepatic cholestasis of pregnancy (attachment removed to protect patient identity) and hence the itching. The parameters have deranged and AST (aspartate aminotransferase), ALT (alanine aminotransferase) and Alkaline phosphatase have increased because the dose of Udiliv (Ursodeoxycholic acid) being prescribed has been low. Please consult your specialist doctor, discuss with him or her and get the dosage increased. Then, the liver function test can be repeated again after a week. Also, remember that in cases of IHCP, pregnancy should be terminated at 37 week period of gestation and should not be allowed to continue further for the chances of complication.

Answer 2

Hello,

Welcome back to icliniq.com.

Yes, it is very much safe. One can go up to 1200 mg daily as well if the liver parameters do not respond.