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I am a woman with PCOS/PMOS on Diane. How soon will periods come?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have PCOS/PMOS and irregular periods. My doctor prescribed me Diane-35 for 21 days. The last day of the pill was 15 days before. I have not gotten my period to date. I did a home pregnancy test, and it is negative.

Though it is unlikely that I will be pregnant. I wanted to know how long to wait for the periods to come with Diane-35?

Please clarify.

Answered by Dr. Amit Kyal

Education:

MBBS

Professional Bio:

Dr. Amit Kyal is a highly respected Gynecologist and Obstetrician known for his expertise in infertility management, high-risk pregnancy care, and advanced endoscopic surgery. He is recognized for his patient-centered approach, combining clinical knowledge with compassion and professionalism. Dr. Kyal listens attentively to his patients’ concerns, provides clear guidance, and delivers treatments based on the latest evidence-based practices. His holistic approach ensures that patients feel supported both medically and emotionally throughout their care. With a strong commitment to continuous learning and women’s health, Dr. Amit Kyal has established himself as a trusted and leading specialist in gynecology and obstetrics.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

Diane-35 (Ethinylestradiol and Cyproterone) is taken for 21 consecutive days with seven days off. The next cycle is started after seven days off on the eighth day, irrespective of the periods. Though in the majority of cases there are periods in those seven days, there may not be periods.

Hope your other investigations, mainly CBC (complete blood count), blood sugar, TSH (thyroid stimulating hormone), and Prolactin, are normal.

PCOS/PMOS (polycystic ovarian syndrome/Polyendocrine metabolic ovarian syndrome) also requires lifestyle modification, which includes avoiding a high-calorie diet, regular exercise, and brisk walking.

I hope this helps.

Thank you.

Patient's Query

Hello doctor,

Thank you for your response.

Recently, I took a blood report, which shows low prolactin. Does it have any effect? Also, please let me know if there is any possibility for periods to come in the next couple of days.

Kindly suggest.

Answered by Dr. Amit Kyal

Education:

MBBS

Professional Bio:

Dr. Amit Kyal is a highly respected Gynecologist and Obstetrician known for his expertise in infertility management, high-risk pregnancy care, and advanced endoscopic surgery. He is recognized for his patient-centered approach, combining clinical knowledge with compassion and professionalism. Dr. Kyal listens attentively to his patients’ concerns, provides clear guidance, and delivers treatments based on the latest evidence-based practices. His holistic approach ensures that patients feel supported both medically and emotionally throughout their care. With a strong commitment to continuous learning and women’s health, Dr. Amit Kyal has established himself as a trusted and leading specialist in gynecology and obstetrics.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Low prolactin does not cause this problem. This may happen with PCOS/PMOS (polycystic ovarian syndrome/Polyendocrine metabolic ovarian syndrome), which is associated with obesity and high androgen levels. As you have taken the medications regularly for 21 days, pregnancy is also unlikely.

However, I suggest you do a urine test for pregnancy once more. It is difficult to say whether periods will come in the next few days or not. You should start the second cycle of Diane 35.

I hope this helps.

Thank you.

Patient's Query

Hello doctor,

Thank you.

Can you please tell me when I should start the next dosage? My last pill was on the 10th of this month. Having completed 14 days, can I start taking the next pack from today or tomorrow?

Please suggest.

Answered by Dr. Amit Kyal

Education:

MBBS

Professional Bio:

Dr. Amit Kyal is a highly respected Gynecologist and Obstetrician known for his expertise in infertility management, high-risk pregnancy care, and advanced endoscopic surgery. He is recognized for his patient-centered approach, combining clinical knowledge with compassion and professionalism. Dr. Kyal listens attentively to his patients’ concerns, provides clear guidance, and delivers treatments based on the latest evidence-based practices. His holistic approach ensures that patients feel supported both medically and emotionally throughout their care. With a strong commitment to continuous learning and women’s health, Dr. Amit Kyal has established himself as a trusted and leading specialist in gynecology and obstetrics.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Ideally, it should have been started on the 18th of this month. However, start again from tomorrow after doing a urine test for pregnancy.

I hope you find this helpful.

Thank you.

Answered by Dr. Amit Kyal
Medically reviewed by iCliniq medical review team
Published At October 28, 2019
Reviewed At May 29, 2026

Education:

MBBS

Professional Bio:

Dr. Amit Kyal is a highly respected Gynecologist and Obstetrician known for his expertise in infertility management, high-risk pregnancy care, and advanced endoscopic surgery. He is recognized for his patient-centered approach, combining clinical knowledge with compassion and professionalism. Dr. Kyal listens attentively to his patients’ concerns, provides clear guidance, and delivers treatments based on the latest evidence-based practices. His holistic approach ensures that patients feel supported both medically and emotionally throughout their care. With a strong commitment to continuous learning and women’s health, Dr. Amit Kyal has established himself as a trusted and leading specialist in gynecology and obstetrics.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Amit Kyal is a highly respected Gynecologist and Obstetrician known for his expertise in infertility management, high-risk pregnancy care, and advanced endoscopic surgery. He is recognized for his patient-centered approach, combining clinical knowledge with compassion and professionalism. Dr. Kyal listens attentively to his patients’ concerns, provides clear guidance, and delivers treatments based on the latest evidence-based practices. His holistic approach ensures that patients feel supported both medically and emotionally throughout their care. With a strong commitment to continuous learning and women’s health, Dr. Amit Kyal has established himself as a trusted and leading specialist in gynecology and obstetrics.

This doctor is not available for online consultations on the platform anymore.

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