Post-exposure Prophylaxis

Post-exposure prophylaxis (PEP) is a short antiretroviral course taken in an attempt to prevent HIV infection after a possible exposure. It can be taken after suspected exposure due to unprotected sexual intercourse or occupational exposure.

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Do I need post-exposure prophylaxis for HIV after open mouth kissing, and hand masturbation?

Query: Hello doctor, Do I need post-exposure prophylaxis for HIV after the following exposures: 1) Open mouth or french kissing. 2) Handjob and hand masturbation. Have there been known cases of HIV transmission after such exposures?  Read Full »

Dr. Kakkar

Dermatologist, HIV AIDS Specialist, Venereologist

Answer: Hello, Welcome to I have noted your concern. There is no risk of HIV transmission from the open mouth or deep kissing or skin to skin contact as in a handjob. They do not qualify as a risk for HIV transmission. Hence there is no need for post-exposure prophylaxis.   Read Full »

I am having belly fat after taking antiretrovirals. Please advise.

Query: Hello doctor, I am HIV negative and have been taking Truvada and Tivicay now for exactly one month but have stopped. I am pretty regular at the gym and maintain a consistent weight of about 146 to 149. Over the past month, I have gained about 5 lbs. At times my stomach looks pregnant and it is al...  Read Full »

Dr. Ravinder Kaur Sachdeva

HIV AIDS Specialist

Answer: Hi, Welcome to I wanted to ask you whether you had taken Truvada and Tivicay as post-exposure prophylaxis? Belly fat changes which you have developed is one of the side-effect of antiretrovirals which you had taken. The mechanism underlying is not known. As you are not taking medicin...  Read Full »

I am under PEP. How often should I get tested for HIV if the results come negative?

Query: Hi doctor, I am 32 years old. I am on PEP that has to be taken for 28 days. I got my first dose around 40 hours of being contracted to HIV. PEP is not 100 % secure. My question is if I am lucky and the result shows HIV negative after the therapy, how often do I need to get antibody tested if luck s...  Read Full »

Dr. Ravinder Kaur Sachdeva

HIV AIDS Specialist

Answer: Hi, Welcome to The answers to your queries are: For PEP (post-exposure prophylaxis) efficacy, adherence to the medications prescribed for PEP is the most important thing. PEP is really efficacious, To the best of my clinical practice, I have not seen any case of a patient who has comp...  Read Full »

What are the tests and precautions to be taken for HIV after unprotected sex?

Query: Hi doctor, Yesterday night I had sex with some unknown person. While doing sex my condom got tear and I had removed my penis at the same time and I had lip lock kiss too. I am scared of HIV, could you please guide me what all the precautions I have to take and what all tests I have to take to get t...  Read Full »

Dr. Kiran Anaparthi

Family Physician, HIV AIDS Specialist

Answer: Hi, Welcome to As I can see that the episode is recent in time, I would suggest you use post-exposure prophylaxis (PEP) as early as possible within 72 hours of exposure. The chances of HIV transmission are related to the status of your partner and viral load of partner (if she is posi...  Read Full »

Does Nimesulide affect HIV post-exposure prophylaxis treatment?

Query: Hello doctor, I am on a post-exposure prophylaxis. Today is the eighth day. Today I was diagnosed with tonsillitis. The doctor told me to take Nimesulide. Does it make HIV treatment fail? Please, help me.  Read Full »

Dr. Rakesh Kumar Bahunuthula

Cosmetologist, Dermatologist, HIV AIDS Specialist, Venereologist

Answer: Hi, Welcome to It depends upon what drugs you have been given as post-exposure prophylaxis. Nimesulide does have a few drug interactions although not to the extent of causing drug failure. Kindly mention the drugs you are using for PEP.  Read Full »

What are the chances of getting HIV through vaginal sex?

Query: Hello doctor, A guy penetrates my vagina without protection and I do not know his status. It was for approximately for 10 seconds. What are the chances of contracting HIV and should I get a PEP?  Read Full »

Dr. Ravinder Kaur Sachdeva

HIV AIDS Specialist

Answer: Hi, Welcome to You had a low risk for HIV acquisition. Studies have shown that risk of HIV acquisition through receptive vaginal sex (receiving the penis in vagina) to be 0.08 % (one per 1250 exposures). Post-exposure prophylaxis needs to be started as early as possible within 72 hour...  Read Full »

Can I get HIV even after taking PEP?

Query: Hi doctor, Is PEP effective after a risk exposure?  Read Full »

Dr. Kakkar

Dermatologist, HIV AIDS Specialist, Venereologist

Answer: Hi, Welcome to It is not 100 % protective against HIV. But it significantly reduces the chances by over 80 %. Please mention about the mode of exposure.  Read Full »

Started PEP after 66 hours of unprotected sex. Will it be helpful?

Query: Hi doctor, I had unprotected sex and have consulted a doctor after that. He told me to go for PEP immediately. So, I started PEP after three days of exposure with one Tablet of Lamivudine and Zidovudine along with one Efavirenz tablet. I have taken PEP after 66 hours of exposure. Will it be helpful?...  Read Full »

Dr. Bharat Udey

Geriatrician, Psychiatrist, Sexologist, Sleep Medicine Physician

Answer: Hello, Welcome to PEP (post-exposure prophylaxis) is highly effective if taken within first 12 hours of exposure. However, efficacy is high enough if taken within 72 hours of exposure as well. Efficacy decreases afterwards. As you have started PEP within 66 hours of unprotected coitus,...  Read Full »

What is PEP therapy for HIV?

Query: Hello doctor, I had an exposure with a call girl with protection. However, during intercourse, the condom broke. I am worried about HIV. Could you please guide me regarding what kind of tests I should undertake. Also, I would like to understand how many days later I should go for the test. As on tod...  Read Full »

Dr. Jyotisterna Mittal

Dermatologist, Venereologist, HIV AIDS Specialist, Cosmetologist, Family Physician, General Practitioner

Answer: Hello, Welcome to A fourth generation ELISA (enzyme-linked immunosorbent assay) test for HIV (human immunodeficiency virus) should be done at six weeks and then after 12 weeks after exposure. Meanwhile, you can take PEP (post-exposure prophylaxis) therapy for HIV as a preventiv...  Read Full »

Which is the confirmatory test for HIV?

Query: Hi doctor, I am a 29 year old male. I had a very brief unprotected encounter with an escort. I do not know her HIV status. I did ask her afterward and she told me she was clean of STDs. I offered to pay her well just to get an HIV status and she has not responded. I do not know if this is becaus...  Read Full »

Dr. Atishay Bukharia

Cosmetologist, Dermatologist, Family Physician, General Practitioner, HIV AIDS Specialist, Venereologist

Answer: Hello, Welcome to Your exposure was not sufficient enough to acquire human immunodeficiency virus (HIV virus). Frankly speaking I have not seen a single case of HIV with such a short exposure. Oral sex particularly from the donor point of view is considered as safest sexual practice as ...  Read Full »

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