Common "Post-exposure Prophylaxis" queries answered by top doctors | iCliniq

Post-exposure Prophylaxis

Post-exposure prophylaxis (PEP) is a short antiretroviral course taken in an attempt to prevent HIV infection after a possible exposure. It can be taken after suspected exposure due to unprotected sexual intercourse or occupational exposure.

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I had a few symptoms after oral sex. Could I be HIV-positive?

Query: Hello doctor, Six months back, I had oral intercourse with two women and an unprotected erotic massage by a worker with her saliva and vaginal secretions to stimulate my penis. Two months later, I was in contact with a woman without sexual intercourse, during which one of her body piercings struck m...  Read Full »


Dr. Basti Bharatesh Devendra

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. The HIV (human immunodeficiency virus) test is negative repeatedly and after three months of last risk exposure, except for the reused needle risk, as mentioned. Usually, all healthcare professionals are trained in uni...  Read Full »

I had sex with a sex worker and started PEP after 48 hours. What are my chances of getting HIV?

Query: Hi doctor, I had two sexual encounters nine days back. I had sex with a sex worker unknowingly. My penis is uncircumcised, and my condom broke while having vaginal sex. I also ejaculated inside her. After the session, within 48 hours, I consulted a doctor and started PEP, so what are my chances here...  Read Full »


Dr. Sandhya Narayanan Kutty

Answer: Hi, Welcome to icliniq.com As per the history provided, in case of possible exposure to HIV infection, antibody testing would not suffice. Initially, when infected, the viral load with RNA (ribonucleic acid), which is the genetic material of the virus, along with a protein called p24, is released ...  Read Full »

I am experiencing symptoms after taking PEP. Please help.

Query: Hello doctor,I tested negative for HIV (human immunodeficiency virus)-1 & 2 using a fourth-generation test on day 22, day 27, and day 35 after the first exposure. I was immediately placed on PEP (post-exposure prophylaxis), due to a second exposure which was after a month. I completed 17 doses o...  Read Full »


Dr. Basti Bharatesh Devendra

Answer: Hello,Welcome to icliniq.com.I understand your concern. If an HIV (human immunodeficiency virus) antibody test conducted in a reliable laboratory after 90 days from the last risky exposure yields a negative result, then it is considered conclusive, provided there have been no further risky exposures...  Read Full »

My partner is HIV positive, and we had sex a few days back. Should I begin with PEP medications?

Query: Hello doctor, My partner turned HIV positive when he was tested five months ago. I tested previously, and it was negative. My partner and I decided not to have intercourse till my reports came in. However, last night we had quick intercourse wearing a condom. It was the correct way and for less than...  Read Full »


Dr. Basti Bharatesh Devendra

Answer: Hello, Welcome to icliniq.com. Thanks for writing in, and I understand your concern. The chances of transmission of the human immunodeficiency virus (HIV) by single protected intercourse with an HIV-positive person are almost nil. If there is no contact of blood or semen or infected secretions, th...  Read Full »

Had anal sex with an HIV-positive person. What is the chance of infection?

Query: Hi doctor, My partner is HIV(Human Immunodeficiency Virus) positive. We had anal rubbing, but we used protection (condom). Also, there was no discharge and not even precum. The anus was also dry during that time. What is the chance of me getting affected?  Read Full »


Dr. Rakesh Kumar Bahunuthula

Answer: Hi, Welcome to icliniq.com. A known case of HIV (Human Immunodeficiency Virus) is always a potential candidate for transfer of infection. However, the infectivity levels differ according to his stage of disease, CD4 count and viral load titers. Anal intercourse does have a higher risk of disease tr...  Read Full »

What are the chances of getting HIV through vaginal sex?

Query: Hello doctor, A guy penetrates my vagina without protection and I do not know his status. It was for approximately for 10 seconds. What are the chances of contracting HIV (Human Immunodeficiency Virus) and should I get a PEP (Post-exposure Prophylaxis)?  Read Full »


Dr. Ravinder K. Sachdeva

Answer: Hi, Welcome to icliniq.com. You had a low risk for HIV acquisition. Studies have shown that risk of HIV acquisition through receptive vaginal sex (receiving the penis in vagina) to be 0.08 % (one per 1250 exposures). Post-exposure prophylaxis needs to be started as early as possible within 72 hour...  Read Full »

My condom broke during intercourse. Will i contract HIV?

Query: Hello doctor,I am concerned about having intercourse with an unknown partner as the condom broke in between. We are not sure if this incident happened immediately before penetration or after it. I swiftly left after this incident as it started to worry me. She did mention that she tests regularly. D...  Read Full »


Dr. Vandana Andrews

Answer: Hello, Welcome to icliniq.com. I can understand your concern. It is essential to remember that the risk of contracting HIV (human immunodeficiency virus) through a single act of unprotected intercourse is low, especially if the other person has tested negative for HIV and is practicing safe sex. Ho...  Read Full »

What are the side effects of post-exposure prophylaxis?

Query: Hello doctor, I had unprotected vaginal sex with a woman 17 hours ago, and I am worried that I may have contracted HIV. I say this because I have learned that the woman I had sex with has multiple sexual partners, and I am anxious she may have HIV. I am not in a position to ask her if she has HIV, ...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your post. I understand it is a difficult situation. However, because the PEP (post-exposure prophylaxis) is time-dependent. So, I suggest the first thing you should do would be to start PEP right away, as it may not be helpful after 72 hours. Also, if t...  Read Full »

What are the chances of getting HIV after taking post-exposure prophylaxis?

Query: Hello doctor, I have done some stupid things in my life. I had safe sex, but with many different girls. There was never a condom fail and each time I used a new condom. When I did it with the fourth girl, I noticed that the condom tip was broken. After that, I took PEP. On the 26th day post exposure...  Read Full »


Dr. Ashok Kumar

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concerns. In my opinion, the chances of you getting an HIV (human immunodeficiency virus) infection is 0.001 % or less. I am glad to note that you have used a condom every single time and took all possible precautions. In fact, you...  Read Full »

I am in PrEP on demand. Should I start PEP in addition?

Query: Hello doctor, I am in PrEP on demand. This week, I took the protocol as indicated (two initial doses, one dose the next day, and two more every day for 48 hours after sex). In the sexual relationship, the condom was broken, and I did not realize it. I am nervous even though I fulfilled the protocol...  Read Full »


Dr. Basti Bharatesh Devendra

Answer: Hi, Thank you for stopping by! I am here to provide expert opinion on your medical issues. The chances of transmission of HIV (human immunodeficiency virus) through single unprotected intercourse are low. Condom breakage can be considered almost as unprotected intercourse, though the risk in your...  Read Full »

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