Patient's Query
Hello doctor,
I had an exposure with a sex worker while using protection. However, during intercourse, the condom broke. I am worried about HIV (Human Immunodeficiency Virus). Could you please guide me on which tests I should undergo? I would also like to know how many days after exposure testing should be done.
As of today, it has been 24 hours since the exposure. Kindly guide.
Hello,
Welcome to icliniq.com.
A fourth-generation ELISA (enzyme-linked immunosorbent assay) test for HIV (human immunodeficiency virus) should be done at six weeks and again at 12 weeks after exposure.
Meanwhile, post-exposure prophylaxis (PEP) therapy can be started as a preventive treatment for HIV. This therapy usually includes a combination of antiretroviral medicines and should be started within 72 hours of exposure.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
No test can detect HIV (Human Immunodeficiency Virus) at such an early stage. An HIV RNA reverse transcription polymerase chain reaction (RT-PCR) test or a qualitative HIV deoxyribonucleic acid (DNA) polymerase chain reaction (PCR) test can detect infection about one to two weeks after exposure.
A fourth-generation ELISA (enzyme-linked immunosorbent assay) test can detect infection at around four to six weeks after exposure. However, tests done very early may sometimes yield false-positive or false-negative results. Therefore, a final fourth-generation ELISA test at 12 weeks after exposure is recommended for confirmation.
Post-exposure prophylaxis (PEP) therapy is used to prevent HIV infection after a high-risk exposure. It usually consists of a fixed-dose combination tablet containing Lamivudine 300 milligrams, Tenofovir disoproxil fumarate 300 milligrams, and Efavirenz 600 milligrams.
This medication is taken once daily for 28 days, preferably at night, about two hours after dinner. Fatty foods should be avoided with the evening meal. No dose should be missed. PEP therapy should be started as soon as possible after exposure to be effective; it is less effective if started after 72 hours of exposure.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
Post-exposure prophylaxis (PEP) for HIV (Human Immunodeficiency Virus) can be obtained from any well-stocked pharmacy or hospital pharmacy. It is appropriate to start the treatment from tomorrow, as it is still within the recommended time window. This therapy may cause side effects such as nausea, vomiting, diarrhea, fatigue, headache, and dizziness. Most side effects are usually mild and temporary.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
Yes, this treatment is started even before knowing the results of the HIV (Human Immunodeficiency Virus) test, as it is used for prevention. It is effective only against HIV and not against other viruses. The medicine should not be stopped if the side effects are mild and tolerable, as this combination is one of the most effective options for preventing HIV infection. However, if the side effects are severe or intolerable, the medication regimen may need to be changed under medical supervision.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
I can start the medicine from tomorrow and will continue it for 28 days. I will then undergo the test as recommended. Does this medicine guarantee 100% prevention?
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
Nothing in medicine is absolute. Research has shown that post-exposure prophylaxis (PEP) for HIV (Human Immunodeficiency Virus) is approximately 90% effective, but it does not provide 100% protection.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
For how long should this medicine be taken?
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
The medication should be stopped after 28 days. Lifelong treatment is required only for individuals who are confirmed to be infected with HIV (Human Immunodeficiency Virus).
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
When can the tests be done? Also, could you please explain the symptoms of HIV (Human Immunodeficiency Virus) infection?
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
In most patients, there are no symptoms for many years. Some individuals may develop flu-like symptoms, such as fever, headache, sore throat, and body aches, about two to four weeks after infection.
A fourth-generation ELISA (enzyme-linked immunosorbent assay) test for HIV (Human Immunodeficiency Virus) can be done two weeks after completing post-exposure prophylaxis therapy with the fixed-dose combination of Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz. This corresponds to about six weeks after exposure. The test should be repeated at 12 weeks after exposure for confirmation.
If there is significant anxiety, an HIV RNA reverse transcription polymerase chain reaction (RT-PCR) test can be done two to three weeks after exposure. Still, results at this stage may not be entirely reliable.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
Can I take medicines such as Dolo 650 and Azithromycin, which were prescribed by my family doctor for throat pain?
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
Yes, you can take it.
I hope this helps.
Thank you.
Patient's Query
Hello doctor,
I have completed a 28-day course of the medicine. When can I take the test? I am married, and I did not have sexual intercourse during this treatment period. My wife is suspicious because I have been avoiding intimacy for the past month. Can sexual intercourse be resumed with protection before undergoing the test? Which test should be done?
Kindly advise.
Hello,
Welcome back to icliniq.com.
I understand your concern.
You can get tested now and then again after four weeks. The recommended test is a fourth-generation ELISA (enzyme-linked immunosorbent assay) for HIV (Human Immunodeficiency Virus). You can safely resume physical intimacy with your wife.
I hope this helps.
Thank you.
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Answered byDr. Jyotisterna Mittal
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
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