I am an Rh-positive mother with a second pregnancy and received the injection, which I had not received for my first pregnancy. Will it harm my baby?

Q. Will receiving an injection during a second pregnancy of an Rh-positive mother harm the baby?

Answered by
Dr. Uzma Arqam
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jan 24, 2023 and last reviewed on: Jan 25, 2023

Hi doctor,

My blood group is B negative and my husband's blood group is O positive. In my first pregnancy, the hospital diagnosed me with a positive blood rhesus, and was not given any injection. I am in my second pregnancy almost full term and had been given the injection because of the first diagnosis. What will happen to my baby?



Welcome to icliniq.com.

If the mother has negative Rh and the father is positive then there is a chance of antibody development due to an immune reaction in the mother against the fetus. In the case of fetomaternal hemorrhage, this immune reaction could cause fetal anemia. It is remarkable in the case of a positive blood group of the fetus.

Baby could be growth restricted, anemic, and so on. Mostly as the problem is not evident in the first pregnancy, so in the second pregnancy it could be evident if the mother did not receive an anti-D antigen.

Are scans reports of the fetus normal? Baby's weight, growth, and amniotic fluid should be normal, and electronic fetal monitoring to be done recurrently. You can have an antibody titer test and can have anti-D as well. Baby could prone to maternal antibodies in case of fetomaternal hemorrhage as antibody exchange could harm the fetus and could cause anemia, growth restriction, and so on.

I hope you get my point.

Baby blood group should be checked at birth. Mothers should have anyone anti-D after birth as well.

Best of luck.

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