Common "Prostate Biopsy" queries answered by top doctors | iCliniq

Prostate Biopsy

A prostate biopsy is used for removing the suspected prostate tissues with the help of a needle. It is suggested to detect prostate cancer when there is an increased level of prostate-specific antigen, a lump in the physical rectal examination, or if a previous biopsy report stated the presence of abnormal but non-cancerous cells. It can be of two types, namely transrectal and transperineal biopsy. Rectal bleeding, blood in urine, bloody semen, difficulty in urination, and infection are the risks associated with prostate biopsy.

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Why MRI is required after a normal prostate biopsy?

Query: Hello doctor,I am 64 years old, and I just had my first prostate biopsy. Out of 10 samples, only one contained cancer. Gleason 6 (3+3). DRE normal. PSA 4.4. PSA has gone up and down over four years, with 4.5 the highest and 3.75 lowest. Recent 4K score 9 %. Recent PCA3 17 %. I was relieved with the ...  Read Full »


Dr. Khant Shahil Ramesh Bhai

Answer: Hello, Welcome to icliniq.com. Yes, you require an MRI (magnetic resonance imaging). Your urologist wants to keep you on active surveillance. So it is better to make sure that there are no other suspicious lesions or foci which may be missed on biopsy. If there are no foci, then you do not require ...  Read Full »

What are the non-invasive procedures to detect prostate cancer?

Query: Hello doctor, I am a 79 year old male. Excellent health, take no medications with the exception of an occasional Viagra. In a recent DRE, my urologist discovered two small nodules on my prostate. A PSA at the time was 6.3. Over the years, I have ranged in 2's and 3's. He suggested a biopsy of the pr...  Read Full »


Dr. Karthik Rajan

Answer: Hi, Welcome to icliniq.com.I have gone through your query. I concur with your urologist in the need for a biopsy. Any PSA (prostate-specific antigen) more than 4 or abnormal findings on DRE (digital rectal examination) needs evaluation to rule out prostate cancer. None of the non-invasive techniques...  Read Full »

What does calcification in DRE and TRUS indicate?

Query: Hello doctor, Prostate biopsy was prompted by rising PSA over several years (20% to 25% per year) reaching over 4 this past year (spiked at 7.3 which I think really is why they wanted the biopsy but I expect it to come down since then). 12 core came back benign, but I do not understand the implicat...  Read Full »


Dr. Vandana Andrews

Answer: Hi, Welcome to icliniq.com. I have studied your reports and consulted with my pathologist. (attachment removed to protect patient identity). As per her advice and mine too, your reports are normal, the biopsy changes are age related. In the biopsy no carcinoma is identified. Doing DRE (digital recta...  Read Full »

Can anorectal pain with prostate tenderness occur due to prostate cancer?

Query: Hello doctor, I am 35 years old. I developed sudden pain in my anorectal area around two years ago, and I also felt some tenderness on the prostate. However, they did not do anything as I did not have any urinary symptoms. The semen culture was fine. However, I developed urinary symptoms about one ...  Read Full »


Dr. Samer Sameer Juma Ali Altawil

Answer: Hi, Welcome to icliniq.com. MRI (magnetic resonance imaging) showed about 2.5 cm lesion in prostate PI-RADS (Prostate Imaging Reporting And Data System) 5. You had PSA (Prostate-specific antigen) last year, which showed 0.6 ng/ dl. Follow-up PSA and prostate biopsy are two important things to do n...  Read Full »

Why is there brown discharge while emptying the bowel after prostate biopsy?

Query: Hello doctor, I had a transperineal ultrasound-guided prostate biopsy approximately four weeks ago. As a result of the biopsy, I have been getting a discharge of fluid from my penis when I empty my bowels. This happens usually with a hard stool. The color of the discharge is brownish. Is this a no...  Read Full »


Dr. Gajanan Shirpad Bhat

Answer: Hello, Welcome to icliniq.com. Anatomically prostate is located just in front of the rectum. The biopsy procedure would have caused some micro trauma with resultant bleeding. So, when a hard stool passes through the rectum, it puts pressure on the rectum thus causing the collected old blood to com...  Read Full »

My PSA is 5.7 and MRI negative. Should I get prostate biopsy?

Query: Hello doctor, I had a 4.4 PSA and had an MRI that was negative. Six months later my PSA is 5.7 and even though the MRI was negative it is suggested that I should have a prostate biopsy. I am a 73-year-old male. I am certainly not that excited to have a biopsy. Any thoughts?  Read Full »


Dr. Gajanan Shirpad Bhat

Answer: Hi, Welcome to icliniq.com. I can understand your concern about undergoing an invasive investigation without any symptoms. Let me explain you what does PSA suggest. Basically, PSA is secreted by the prostate as well as some other body tissues. It does not reach circulation and hence remains low in b...  Read Full »

There is high PSA level but no symptoms. Is biopsy really necessary?

Query: Hello doctor, My husband needs help. He is a 68-year-old male with a high PSA level of 8.65. It has gone from 5.3 to 8.65 in a year. Now, let me give you the facts. We believe at his age, he might have an enlarged prostate, but none of the two doctors he has seen in the past one year has told him so...  Read Full »


Dr. Karthik Rajan

Answer: Hi, Welcome back to icliniq.com. I have gone through your query and would like to know the size of his prostate on the ultrasound scan. An increase from 5.3 to 8 in a year is significant and so is a nodule in the prostate. A free PSA (prostate-specific antigen) test can give an idea of the possibili...  Read Full »

Which grade is considered as cancerous in the prostate biopsy?

Query: Hi doctor,I took a prostate biopsy before three weeks. Out of 12 samples, one core biopsy sample showed high grade. I read on internet that it is a precancerous stage. My doctor gave multiple treatment options like conventional surgery or cyber knife or radiation oncology. Please help.  Read Full »


Dr. Rajesh Gulati

Answer: Hi, Welcome back to icliniq.com.From the report attached (attachment removed to protect the patient's identity) it shows a high grade precancerous condition, so I suggest surgery. Because radiation has side effects. Before the surgery take PSA (prostate-specific antigen) test every month and repeat ...  Read Full »

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