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Does prostate cancer have a genetic risk?

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Patient's Query

Hello doctor,

I am a 66-year-old male. My biopsy confirmed prostate cancer, and I am concerned about my family’s health. I have two sons in their 30s. Should they start getting tested earlier than normal? Is there a genetic component to my diagnosis that I should discuss with them? Are there specific tests they should consider? Please help.

Thank you.

Answered by Dr. Ali Osman

Hello,

Welcome to icliniq.com.

I can understand your concern.

Prostate cancer is a type of cancer that occurs in the prostate, a small gland in men that produces seminal fluid. Please remember this: as you have prostate cancer, it does not mean that your sons will have cancer. However, they have a family history, so they must reduce other risk factors.

Risk factors for prostate cancer include the following:

  1. Age: The risk of prostate cancer increases with age.
  2. Genetics: Inherited gene mutations are responsible for about five to 10 percent of prostate cancer cases. Other genetic changes acquired during a lifetime can also raise the risk. Therefore, prostate cancer genetic testing is required.
  3. Family history: Having a father or brother who developed prostate cancer before the age of 60 increases the risk.
  4. Obesity: There is evidence that obesity is linked to a higher risk of prostate cancer.
  5. Diet: A diet high in calcium and red meat has been associated with an increased risk of prostate cancer.

I would suggest they undergo annual screening with:

1. Digital rectal examination (DRE).

2. PSA (prostate-specific antigen) level (in some other normal conditions, PSA can also increase, such as infections, inflammation, etc.)

The following are the preventive methods:

  1. They should go for regular checkups.
  2. Maintain a healthy diet.
  3. Maintain a healthy weight.

I hope this helps you.

Thank you.

Answered byDr. Ali Osman

Medically reviewed byiCliniq medical review team

Published At January 20, 2025
Reviewed AtSeptember 12, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ali Osman
Dr. Ali Osman

Obstetrics and Gynecology

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