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HomeAnswersPathologyprotein electrophoresisWhat does it mean if a protein is found in the gamma region?

What is the meaning of a protein found in the gamma region?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Lekshmipriya. B

Published At March 27, 2022
Reviewed AtAugust 7, 2023

Patient's Query

Hello doctor,

What does it mean if a protein is found in the gamma region? It says they are performing electrophoresis immunofixation.

Answered by Dr. Utkarsh Sharma

Hello,

Welcome to icliniq.com.

I have seen the attached report thoroughly (attachment removed to protect the patient's identity). Your serum protein electrophoresis (SPE) results are normal, and you should not be concerned about gamma protein as it is well within the normal range. Serum electrophoresis gives information about different protein classes present in your serum. The gamma region shows your immunoglobulin levels, and a band in that region means a particular type and clone of immunoglobulin is being produced by a particular clone of plasma cells. This can occur in plasma cell dyscrasias. Immunofixation electrophoresis will help in determining the type of immunoglobulin in that band in the gamma region. An original electrophoresis strip could have helped me better identify the sharpness of the band. But there seems nothing to worry about if it was just a routine test since the levels are well within normal range. Take care and stay healthy.

Patient's Query

Hello doctor,

Thank you for the reply.

Answered by Dr. Utkarsh Sharma

Hello,

Welcome back to icliniq.com.

You are most welcome. I wish you health and peace.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Utkarsh Sharma
Dr. Utkarsh Sharma

Pathology

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