Protein In Blood

Protein in the blood is called plasma proteins, which are needed to transport lipids, minerals, hormones, and vitamins to help the immune system's proper functioning. Albumins, globulins, fibrinogen, regulatory proteins, and clotting factors are the families of blood proteins, with each family serving different functions. Therefore, measuring the level of serum proteins by electrophoresis is an essential diagnostic tool.

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What is the reason for the fluctuations in the protein levels in my blood?

Query: Hi doctor, I have been worrying that I have Multiple myeloma, and I cannot stop crying. I am only 27 years old. I have had on and off elevated total protein for the past eight years. Protein was fine before six to seven years, then elevated again. The highest I have seen was the 9.0 range, but it f...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to The following is my opinion on your question: The globulin level is high in the attached report (attachments removed to protect the patient's identity). But elevated protein does not always mean multiple myeloma. It could be due to temporary inflammation a...  Read Full »

How to find the stage of multiple myeloma?

Query: Hi doctor, My 97 year old mother, who is in a nursing home, is more tired and feeling unwell. A blood test has shown she has likely got multiple myeloma. She had left-sided paralysis from a stroke six years ago. She cannot speak, and she is slow in understanding and writing, but she has no dementia...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to Sorry to hear about your mother's condition. I have read all the test values that you have mentioned. From which, I can see that her total protein is high and albumin is low with elevated gamma globulin. Immunofixation electrophoresis is the best test to detect plasma ce...  Read Full »

Kindly give your opinion regarding my CBC report.

Query: Hi doctor, I am a 27 year old male. I would like to get your opinion on my CBC report. Shall I attach my report?  Read Full »

Dr. Prakash H Muddegowda

Answer: Hi, Welcome to Please do attach the report of the CBC (complete blood count). I will be able to comment further once I see it. Revert with the report to a hematologist online -->  Read Full »

What does elevated M protein mean?

Query: Hello doctor,I am wondering about my lab work due to M protein in my blood. I have my lab work available, and I have some questions since I have not been able to get to my doctor.  Read Full »

Dr. Sugreev Singh

Answer: Hi, Welcome to I have gone through your reports (attachment removed to protect patient identity). There were few changes seen like vitamin insufficiency, increased ALT (alanine transaminase), and AST (aspartate transaminase), indicating liver infection or inflammation. Apart from this...  Read Full »

Does total protein count change significantly based on how much protein rich food is eaten?

Query: Hello doctor, I have a question about total protein count in blood, urine, and saliva. My question is, does someone's total protein count change significantly based on how much protein rich food they eat? Or does someone's total protein count not change unless they have an illness like muscle damag...  Read Full »

Dr. Raj Parekh

Answer: Hi, Welcome to The protein is digested in our human body but is sometimes excreted when not digested properly or in excess quantity. The term which you are referring to, which is total protein count in blood, urine and saliva has totally different meaning in all the three mediums. To...  Read Full »

What are the causes of increased blood protein levels?

Query: Hi doctor, I went to the doctor for a general physical examination and did the normal blood work. Everything came back normal, except my blood protein was 8.5 g/dL. She sent me for another blood test today, monoclonal protein test. I am worried sick until I get the test results. Should I be concer...  Read Full »

Dr. Sumit Srivastava

Answer: Hi, Welcome to Your protein level is in the upper normal range. Normal body proteins value can range from 6 to 8.5 g/dL. Increased proteins and monoclonal antibodies are seen in plasma cell disorders, but patients in such cases usually have a fever, back pain, anemia, and a myriad of o...  Read Full »

Why is there raised protein level in ANA positive patient?

Query: Hello doctor, Positive ANA, weak positive Smith through childhood or teens. Monitored for lupus by pediatric rheumatologist but never really exhibited symptoms. I have abnormal beta 2 glycoprotein that puts me at risk for blood clots. Was told in high school to take Baby Aspirin every day. I am now...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to The elevated high total protein does not indicate malignancy only. It could be due to some temporary infective etiology as well. Your all other parameters do not indicate any blood cancer. If you have a history of positive beta 2 glycoproteins as mentioned in the abo...  Read Full »

Why do I have loose skin around eyes?

Query: Hi doctor, I am facing problem of loose skin around eyes. Ophthalmologists have described it to be eye allergy. They have suggested anti-inflammatory drops Systane Ultra, but it did not help. Is this a case of plastic surgery? Also, why has this happened so quickly over a period of five months? I ha...  Read Full »

Dr. Gaurang Gupta

Answer: Hello, Welcome to I have seen your pictures (attachments removed to protect patient identity) and can appreciate the puffiness below both eyes. There are few causes of such puffiness, which I would like to explain in pointwise manner. Excessive sleeplessness (very less sleep) is one of ...  Read Full »

My blood protein levels are in higher range. Is that a precursor of any problem?

Query: Hi doctor, For around seven years, my blood protein levels range from 8 to 8.6. The average of all is 8.29 and nothing showed up in urine. Is this a precursor to something? When I have asked doctors, they all said that it was in guidelines and it is intermittent.  Read Full »

Dr. Prakash H Muddegowda

Answer: Hi, Welcome to Based on your query, my opinion is as follows: Yes, your doctor is right. Variation in protein levels is always present. Only, if the globulin levels are too high, then it is worrisome. If the globulin levels are increasing over time, then you need to be worried. If not, ...  Read Full »

My iron is 4.2 and saturation is 5%. Are my lab values normal?

Query: Hello doctor, My current iron is 4.2 and saturation is 5%. Are there any medications that can help me correct my lab values?  Read Full »

Dr. Smrita Singh

Answer: Hello, Welcome to Turbidity due to proteins, lipids and cellular matter is a potential problem with spectrophotometric estimation of any blood constituent including hemoglobin. The large dilution (1:251) of sample largely eliminates the problem, but falsely raised ctHb (concentr...  Read Full »

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