HomeAnswersHematologyrh incompatibilityRh was given as 'weak D positive'. Does that affect mother or baby?

Rh was given as 'weak D positive'. Does that affect mother or baby?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Singh Smrita

Medically reviewed by

iCliniq medical review team

Published At June 3, 2018
Reviewed AtJune 8, 2023

Patient's Query

Hi doctor,

My wife is pregnant for the first time and it is her 12th week. We did a blood grouping and urine culture testing last week. It is found that the blood group is 'O' but the Rh was given as 'weak D positive'. We did a second opinion testing in a different laboratory and the result was the same. Doctors are confused and they say that we need to check what is the blood group of the baby. We are a little bit worried and the following are our queries.

  1. What type of blood group does she belong to (O+ or O-)?
  2. Does that affect my wife and baby for the first pregnancy?
  3. Do we need to take any preventive measures to make sure everything is normal or post-pregnancy?

Please help us.

Answered by Dr. Singh Smrita

Hello,

Welcome to icliniq.com.

Weak D in itself is a specific category of blood group. Weak D expression primarily results from single point mutations in RhD which encode amino acid changes predicted to be intracellular or in the transmembrane regions of RhD. Molecular RhD blood group typing is very efficient for managing donors and patients carrying any of the various molecular types of weak D and partial D.

Weak D people belonging to weak type 1, 2, 3, 4.0, 4.1, and 5 can be treated as Rh-positive and be transfused by Rh-positive red blood cells, while subjects with weak type 4.2–11 and 15 should be treated as Rh-negative and transfused with Rh-negative red blood cells.

Ideally, it is important to know the status of the blood group of the mother if she is Rh negative so that anti D injections can be given to prevent complications in subsequent pregnancies if the baby is Rh positive. A weak D positive is generally considered as Rh positive and usually, the anti D injections are not required in such patients.

It should not affect either your wife or baby during her first pregnancy and subsequent pregnancies as well.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Singh Smrita
Dr. Singh Smrita

Hematology

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