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Can AB positive and negative blood groups affect the baby?

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Patient's Query

Hi doctor,

My blood group is AB+, and my fiance's blood group is AB-. Will different blood groups create problems in the future regarding the baby's health or other issues?

Kindly help.
Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

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Hi,

Welcome to icliniq.com.

  1. You and your fiancé can marry without any problem. Do not worry about that.
  2. The only thing that has to be done is to check the baby's blood group. As your blood group is Rh negative, if the baby's blood group is Rh positive, then it might lead to Rh incompatibility, which can create hemolytic disease in the second baby.
  3. So, before delivery, anti-D (RHO clone) immunoglobulin is given as prophylaxis.
  4. And it is better to get your fiance's peripheral smear and CBC (complete blood count) done during the antenatal pregnancy period. If hemoglobinopathy is suspected, then HPLC (high-performance liquid chromatography) can be done.

I hope your concern is solved.

Medically reviewed by iCliniq medical review team
Published At April 9, 2017
Reviewed At January 6, 2026

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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Read answers about:

complete blood count (cbc)rh incompatibilityhemolytic diseaseblood health

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