Q. Can Sertraline cause acid reflux, food choking in the throat, and pain while swallowing?

Answered by
Dr. Saumya Mittal
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Mar 16, 2023

Hi doctor,

I started taking Sertraline recently because of severe anxiety, IBS, and light indigestion (feeling heavy after meals). Indigestion has subsided, but not anxiety or IBS. The worse effect of that drug was acid reflux as soon as I took the first pill, and it still persists, and it is worse when I am very anxious. And after a week, I started to have a very tight throat and felt like food was stuck in the middle of it before slowly going down. Now, after two weeks since I started Sertraline, all foods just seem to slow down at the bottom of my throat or behind my chest. It hurts sometimes. I am dying of anxiety and terribly frightened of having esophageal cancer. Are these symptoms due to Sertraline?



Welcome to

I read your query and understand your concern.

This is most likely anxiety related. It cannot be esophageal cancer as there were no symptoms before medicine, and the symptoms are too rapidly progressive for cancer. Usually, it does increase in weeks, but not two weeks. I suggest adding tablet Pantoprazole 40 mg once in the morning, half an hour before food, which can help.

I hope this has addressed your concern.

Kind regards.

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