Drug and Supplements

Pantoprazole - Uses, Dosage and Side Effects

Written by Dr. Vasantha K S and medically reviewed by iCliniq medical review team.

 

Pantoprazole belongs to a group of drugs called proton-pump inhibitors (PPI), which prevent the secretion of stomach acid. They are used in the treatment of ulcers, heartburn, and reflux.

By blocking the enzyme that produces acid, the acid production in the stomach is lowered, thus allowing the ulcers in the stomach and esophagus to heal, thus providing relief from the symptoms.

Uses

  • To heal duodenal and gastric ulcers.
  • To prevent ulcers from forming with the intake of pain-relief medications.
  • To treat reflux disease.
  • As part of triple therapy in H.pylori infection.
  • To treat Zollinger-Ellison syndrome (a condition in which there is over-production of gastric acid).

Possible Side Effects

Allergy: Those allergic to Pantoprazole may develop symptoms such as rashes, swelling of the throat, face or lips and inability to breathe. This is a medical emergency and warrants immediate attention.

Other possible side effects include:

With long-term use, there can be low magnesium levels and vitamin B 12 deficiency.

Dosage

It is normally available in the form of delayed-release tablets or granules.

  • For healing esophageal ulcers and treating acid reflux, the recommended dose is 40 mg daily for four weeks.
  • To treat Zollinger-Ellison syndrome, the dosage is 40 mg twice daily.
  • They are also available in IV form for hospital use.

How to Take?

  1. Usually, it is taken without food for maximum benefit.
  2. It is preferably taken at the same time every day.
  3. Swallow the tablets whole without crushing or splitting them.

Risks

Do not take if:

- you are allergic to PPI.

- you have a severe liver disease.

- you are pregnant, planning for a pregnancy, or breastfeeding.

- you have serious symptoms such as blood in stool, recurrent vomiting, etc.

- you have low magnesium levels.

- you are at risk of osteoporosis.

- you have lupus.

- you take drugs for HIV, certain antivirals, anticoagulants or Methotrexate.

Advantages of Pantoprazole over Other PPIs

  1. Pantoprazole has been proven to improve reflux symptoms and rapidly heal ulcers, the effect being more long-lasting.
  2. It has a lower chance of drug interactions.
  3. It is safe and effective in those with renal and moderate liver disease.
  4. Pantoprazole can be given intravenously in patients who are vomiting.

For more information consult a pharmacologist online --> https://www.icliniq.com/ask-a-doctor-online/pharmacologist

Last reviewed at: 07.Sep.2018

RATING

16
 


Do you have a question on Pantoprazole or Heartburn?
 
* guaranteed answer within 4 hours.
 

Related Questions & Answers


Is tablet Pansec increasing my father's creatinine levels?
Query: Hello doctor, My father is being treated for peptic ulcer, from the past 15 days. So, he is taking a medicine called as Pansec 40 mg, in the morning and evening. He has also developed slight kidney problems, and his creatinine has raised to 1.6. To rule out renal cancer, the doctor will perform ...  Read Full »
Dr. Anshul Varshney
Internal Medicine Physician

Answer: Hi, Welcome to icliniq.com. Pantoprazole belongs to a group of drugs called as proton pump inhibitors, and they are known to cause interstitial nephritis. However, they are not strongly blamed for causing so, but if you want to be on the safer side, it is advisable to switch from Pantoprazo...  Read Full »
 
Taking Pantoprazole for GERD. Is any drug interactions between Pantoprazole and Voltaren?
Query: Hello doctor, I am on 40 mg Pantoprazole twice a day for GERD. I just took 50 mg Voltaren for a bad back and I am worried sick. I checked online and it said no drug interactions. I have not yet taken my nightly dose of Pantoprazole, should I not take it?  Read Full »
Dr. Ashaq Hussain Parrey
Rheumatologist

Answer: Hello, Welcome to icliniq.com. I went through your query. There are no drug interactions between Pantoprozole and Diclofenac (Voltaren). In fact, anyone who takes painkillers like Diclofenac has to take Pantoprazole to prevent Diclofenac-induced gastritis. So, relax and take the regular dose of Pa...  Read Full »
 
How to Treat Heartburn?
Article Overview: This article explains the cause, prevention and treatment of heartburn in detail.  Read Article »
Dr. Muhammad Zohaib Siddiq
Medical Gastroenterologist

Usually at night, we may feel a sour liquid in our throat coming from beneath or burning sensation in our upper tummy. The pain goes up through our chest to the throat. Sometimes we fear it as a heart attack. This is called heartburn or gastroesophageal reflux disease (GERD) in medical terms. How D ...  Read Article »
 
Though I am on treatment for stomach pain, the pain persists. Why?
Query: Hi doctor, I had severe back pain and stomach pain two days ago. I visited my family physician, and he prescribed me Omcar 40 mg along with other medicines. He advised me to take Omcar 40 mg in the empty stomach daily morning, but I took it after lunch and dinner by mistake. Since last 3 hours, I a...  Read Full »
Dr. Ramesh Kumar S
Medical Gastroenterologist

Answer: Hi, Welcome to icliniq.com. Omeprazole (Omcar) and all other proton pump inhibitors are very safe medicines and can be taken for years without any side effect. As you are having pain, antispasmodics like tablet Cibis (combination of Clidinium, Chlordiazepoxide, and Dicyclomine) can be taken thrice...  Read Full »
 
Is Pantoprazole allergy something to be concerned about?
Query: Hello doctor, I had indigestion problems last month and I was given a Pan 40 injection in a 24/7 hospital in my locality. The moment I was given the injection, my body developed rashes, redness, and itching. My doctor immediately gave Avil injection after which rashes and redness subsided. Two days...  Read Full »
Dr. Salah Saad Shoman
Internal Medicine Physician

Answer: Hello, Welcome to icliniq.com. I have gone through your question and I understand your concerns but yes Pantoprazole allergy is a permanent condition that you will need to report to any doctor you visit before prescribing medications. Also, this allergy is nothing to worry about as long as you av...  Read Full »
 
What is the reason for heart burn for four months?
Query: Hello doctor, I am a 35-year-old male having daily heartburn running for more than four months. Currently, having Omeprazole and Domperidone.  Read Full »
Dr. Vandana Andrews
General Practitioner

Answer: Hello, Welcome to icliniq.com. I have gone through your details and I appreciate your concern. It looks like you are having symptoms of GERD (gastroesophageal reflux disease). It occurs when stomach acid goes back into the food pipe. Both acid reflux and heartburn are part of it. An endoscopy can ...  Read Full »
 

Ask a Doctor Online

* guaranteed answer within 4 hours

Related Tags