What could cause an elevation in alkaline phosphatase levels?

Question

Hello doctor,

During routine screening, my ALP was 163. It was repeated at two weeks and four weeks; both times, it was 137. All other liver enzymes are normal and get normal. Ultrasound of upper right quadrant normal. I have the B blood type, and I am a secretor. I looked back, and I had a kidney stone; it was 109. My ALP was 163 again (fasting) at this year's check, and all other liver enzymes were normal. I do not have a history of cancer and no recent fractures. Should I do a further follow-up?

Answer 1

Hi,

Welcome to icliniq.com.

I understand your concern.

Following is my opinion about your asked question. According to the history, your alkaline phosphatase (ALP) is mildly elevated. Usually, the ALP value is high due to liver, kidney, or bone disease. You mentioned that your liver profile and other routine tests are normal. So you should not worry about mild elevated ALP. Sometimes, lifestyle change can help in lowering the ALP. For example, you can take more green leafy vegetables and fruits. Second, it would help if you habitually do regular 20 to 30 minute aerobic exercises. Third, I suggest you visit a nearby physician for your examination and rule out any liver disease, kidney disease, or bone disease if present. If all these three organ examinations and reports are normal, then do not worry about high ALP. You should follow up on the ALP value report after a few weeks.

I hope I have answered your question.

Let me know if I can assist you further.

Best regards.