SGPT stands for serum glutamic pyruvate transaminase. It is an enzyme present normally in liver and heart cells. It gets released into the blood when the liver or heart becomes damaged. High levels of SGPT in the blood indicate liver damage. Conditions like cirrhosis, celiac disease, diabetes, heart attack, and hepatitis show raised blood serum SGPT levels. The symptoms of high SGPT levels are vomiting, nausea, weakness, fatigue, leg swelling, and shortness of breath. To reduce SGPT levels, taking diet modification with vitamin D is necessary.

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Is there a permanent cure for my prolonged macrocytosis?

Query: Hello doctor, I have had macrocytosis for a long time. My last B12 and folate levels were high. I have symptoms of nervousness, snarkiness, light headedness, palpitations, and sometimes tingling in the hands and feet. It is making me crazy. My MCV is 104.9, MCH 35.6 and last TSH 2.18. I have con...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to Macrocytosis can be present because of hypothyroidism, alcohol, liver disease, etc. Your TSH value is within the limit. So, I do not think a thyroid problem can be the cause. You can get the following tests to rule out liver and kidney problem: SGOT (serum glutamic oxa...  Read Full »

I have grade 2 fatty liver. Can I reduce my SGPT levels to normal in just 10 days?

Query: Hello, I have a grade 2 fatty liver as per my abdominal ultrasound test conducted. Currently, I take Liv.52 tablets daily. Last week I visited a medical center to obtain a medical certificate for a medical visit to another country. But they refused to provide a medical certificate as my SGPT level i...  Read Full »

Dr. Alexander Davis

Answer: Hello, Welcome to I read your query and understand your concern. Half the world has a fatty liver. Non-alcoholic fatty liver disease (NAFLD) is as common as high blood pressure. It is not good but not dangerous as long as you do not have signs of inflammation or non-alcoholic steatoh...  Read Full »

I have recurrent changes in my bilirubin level and have pain in my stomach every six months. Why?

Query: Hi doctor,For some time, my digestive system is not so good. I feel swelling near my stomach area. I did the LFT test, bilirubin - 1.4, SGOT - 71, SGPT - 115 , alkaline phosphatase- 205 , triglycerides- 171 and ESR- 16 in range of 0-9, and my platelets 1.25. I feel like vomiting all the time. Someti...  Read Full »

Dr. Sugreev Singh

Answer: Hi, Welcome to I have gone through your reports (attachments removed to protect the patient's identity), and ESR (erythrocyte sedimentation rate) is fine, but your liver enzymes are elevated. Elevated bilirubin and SGPT (serum glutamic-pyruvic transaminase) and SGOT (serum glutami...  Read Full »

Do increased levels of RBC and vitamin B12 cause polycythemia vera?

Query: Hi doctor, My RBC levels have been slightly elevated for the past six months. It was 5.17 a year back, and a couple of months back it was 5.39. I noticed that from the last two years, the RBC count has been borderline high. Last week my vitamin B12 was tested due to a nerve issue in my face, which ...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to I appreciate your knowledge and awareness towards your health, and I have seen your reports (attachment removed to protect patient identity). Your vitamin B12 level is certainly high, enough that warrants further investigation. Following are the common causes for high vit...  Read Full »

What are the possible causes of pain in the right upper quadrant of the abdomen?

Query: Hello doctor, I am 59-years-old male, and I have pain in the right upper quadrant of my abdomen. My laboratory tests shows hemoglobin of 10.6 g/dL and my SGPT is 54.1 units/L, SGOT is 43.63 units/L, FBS is 175 mg/dL. Kindly help.  Read Full »

Dr. Manisha Auradkar Raghunath Auradkar

Answer: Hello, Welcome to I can understand your concern. Pain in the upper right quadrant is associated with different organs like the liver in hepatomegaly, gall bladder in case of stone or inflammation, and duodenal ulcers. Identifying the exact cause by doing laboratory tests is no...  Read Full »

Why do I have increased vitamin B12 levels along with high MCV, MCH, and MCHV?

Query: Hi doctor, I have high MCV, MCH, and MCHV. I also have high B12 levels. What does this mean? I have stomach upset, diarrhea and I pass stool after every meal within an hour. My stool seems to be yellow or orange-brown in color. I have a past history of food intolerance and allergy. Currently, I a...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to Following is my opinion for your asked question. In the attached report (attachment removed to protect patient identity), MCV (mean corpuscular volume), MCH (mean corpuscular hemoglobin), and MCHC (mean corpuscular hemoglobin concentration) is in high range within borde...  Read Full »

My 2-year-old daughter is having high SGPT. Does it indicate liver damage?

Query: Hi doctor, My 2 year old daughter had an abscess on left side of her face.  We got it operated and the biopsy result found to be tuberculosis. But, 45 days of TB culture report came back negative. It was operated a year ago and she was started on TB drug. The medicines prescribed were tablet Macox...  Read Full »

Dr. Sirisha

Answer: Hello, Welcome to Your daughter is getting all the medication required for TB (tuberculosis). The medication does have some side effects like the liver enzymes SGPT (serum glutamic-pyruvic transaminase) and SGOT (serum glutamic-oxaloacetic transaminase), which were done was raised. Slig...  Read Full »

Is there a connection between diabetes and low platelet count?

Query: Hi doctor, I have a low platelet count, but my hemoglobin level is normal. The platelet count was checked electronically. I had papaya extract medication for 12 days still the count remains the same. Please help me.  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to Your platelet count is low. It would be best if you ruled out the underlying cause for that. You can investigate with the following investigations for further workup. 1) Dengue NS 1 and IgM (immunoglobulin M) ELISA (enzyme-linked immunosorbent assay). 2) Urea, cre...  Read Full »

What is the cause for this chronic bleeding from the nose when there is no history of trauma?

Query: Hi doctor, My son is 12 years old. His weight is 40 kg. The problem is bleeding from the nose for the past six years, no habit of nose picking, no history of trauma, bleeding starts at any time of the day, and also without any physical work during sleeping or inactivity. I have consulted with many ...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to Following is my opinion on your asked question. In the attached reports (attachments removed to protect the patient's identity), aPTT (activated partial thromboplastin time) value is high. So hemophilia and other coagulation factor deficiencies have to be ruled ...  Read Full »

Why do I have deranged levels of SGOT, SGPT, homocysteine, and vitamin D?

Query: Hi doctor, I had a recent complete blood checkup. In the report, the levels of SGOT, SGPT, homocysteine and vitamin D levels are abnormal. I have attached the report. The values of SGPT and SGOT are on the higher side, whereas the values of homocysteine, HDL and vitamin D are below normal. Please re...  Read Full »

Dr. Prathap

Answer: Hi, Welcome to Your reports are almost normal (attachment removed to protect patient identity). There is no need to worry. Coming to the rise in SGOT (serum glutamic oxaloacetic transaminase) and SGPT (serum glutamic pyruvic transaminase), the value is significant only when there is mor...  Read Full »

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