What does a weak positive VDRL TPHA test indicate?

Question

Hi doctor,

I am a 24 year old male. Before a month, I visited a hospital in my hometown for pain on the penis. They conducted VDRL and TPHA test and said that the test came back as weak positive. So, it is the first stage of syphilis. They prescribed me an injection and some tablets for five days.

After 10 days, I moved to my place and got both VDRL and TPHA tests in a reputed diagnostic center and the tests came back negative. But, I have taken the medicines prescribed to me. Now, I am getting some neck pain and headache. Can that be a side effect of those medications?

Please help.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

TPHA (Treponema pallidum hemagglutination) is a test to detect treponemal antibodies, which are produced by the body against the bug that causes syphilis. The point is that TPHA is known to show false positive results for some reasons and hence, any positive reaction should be confirmed with TPI (treponemal immobilization) or FTA-ABS (fluorescent treponemal antibody absorption) particularly in asymptomatic patients.

Good that you have tested negative. About your pain, do not worry and it is not definitely due to treatment. I suggest you tablet Paracetamol 500 or 650 mg for neck pain and headache. Sleep well and do not be anxious. It would be great if you could send the medicines and injection you have used.

I hope this helps.

Thank you.

Answer 2

Hello,

Welcome back to icliniq.com.

It seems that you have been prescribed with antispasmodic that is a painkiller and antibiotics Amoxiclav (Amoxicillin and Clavulanic acid) (attachment removed to protect patient identity). Your pain may be due to physical exertion, anxiety, dehydration or improper and incomplete sleep. Have some good sleep, drink plenty of fluids as well and stay hydrated.

Thank you.