Common "Tricyclic Antidepressants" queries answered by top doctors | iCliniq

Tricyclic Antidepressants

Tricyclic antidepressants help to treat depression and manage various other conditions, ranging from obsessive-compulsive disorder to bedwetting. The most commonly prescribed tricyclic antidepressants are Clomipramine, Amoxapine, Desipramine, etc., and it may result in some common side effects such as weight gain, dizziness, dry mouth, constipation, and blurred vision.

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All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Can high doses of antidepressants cause anxiety and fear?

Query: Hello doctor, I am a 40-year-old female and I was taking the tablet Flunil 80 and Clonil 75 four times a day which is 300 mg. At this high dose, I am feeling relapse and struggling with anxiety and fear. Recently I have been promoted to a higher post that requires alertness and fast decision-making...  Read Full »


Dr. Kaushal Bhavsar

Answer: Hello, Welcome to icliniq.com. I can understand your concern. I have gone through the detailed history you have given. I suggest you take a tablet of Propranolol and Flunarizin combination once a day at night before going to sleep. Also, start counseling sessions as counseling plays a very importa...  Read Full »

I have been suffering from mood changes while on my antidepressant medication, which I think I no longer need. Is that fine?

Query: Hello doctor, For 20 years, I have taken the tricyclic antidepressant desipramine intermittently for significant depression. In the past, I could go off the medication when I no longer needed it, but over the last year, I have noticed that when I increase the dose, I feel more depressed, and when I ...  Read Full »


Dr. Seikhoo Bishnui

Answer: Hi, Welcome to icliniq.com. I read your query and understand your concern. As you continue to take antidepressants, their effects may become less noticeable, and your body might develop tolerance to their benefits and side effects. To stay safe, avoid adjusting the dosage on your own. Always take t...  Read Full »

Can tablet Imipramine be the reason for my oversedation?

Query: Hello doctor, I was on tablet Imipramine for a year. Though it worked wonders for my depression, I could not get out of bed until 10 AM daily. So, I switched to tablet Amitriptyline three weeks ago to help me get up early in the morning. However, with tablet Amitriptyline use, I am gaining weight ...  Read Full »


Dr. Vishal Anilkumar Gandhi

Answer: Hello, Welcome to icliniq.com. I understand your concern. You have side effects of tablet Imipramine (Imipramine Hydrochloride) and tablet Amitriptyline. Are you cross-tapering under the guidance of a doctor? If you have an oversedation issue, you must stop or decrease the dose of the tablet Ativa...  Read Full »

Please suggest the best medicine for my psychological disorders.

Query: Hi doctor,I would like to know some treatment recommendations for my condition. I have bipolar disorder type II, social and generalized disorder, and panic disorder. I am having depression for a year. My hypomania is very mild and short-lived. I am afraid to get out of my home due to my constant anx...  Read Full »


Dr. Parth Nagda

Answer: Hi, Welcome to icliniq.com. Regarding your anxiety symptoms, you have tried taking SSRI (selective serotonin reuptake inhibitor) and SNRI (serotonin-norephedrine reuptake inhibitor) class of medications. I suggest you try taking TCA (tricyclic antidepressants) class of antidepressants like Amitrip...  Read Full »

Is the difficulty in achieving orgasm caused by antidepressants temporary?

Query: Hello doctor, I am a 51 year old house wife married since 24 years. I am healthy and maintain a normal life and do my routine household work every day. I do yoga for one hour regularly under a trainer. Though I am yet to have my menopause, I have been experiencing the symptoms of menopause like hot...  Read Full »


Dr. Ashok Kumar

Answer: Hello, Welcome to icliniq.com. I read your query and understand your concerns. First of all, I would like to inform you that it cannot be considered normal and it is probably the side effect of the medication. Clonil (Clomipramine) is a well-established cause for delayed ejaculation in men and t...  Read Full »

What is the treatment option for bipolar 2 disorder with more depressive episodes?

Query: Hello doctor, I have bipolar disorder II and diagnosed with social and generalized anxiety disorders. Currently, my medication fails to uplift my depression. I take lithium 3x450 mg, Olanzapine 5 mg, Escitalopram 20 mg. Previously I tried Valproic acid, Carbamazepine, Topiramate, Zoloft, Prozac, C...  Read Full »


Dr. Parth Nagda

Answer: Hello, Welcome to icliniq.com. Yes, bipolar depression is difficult to treat and it can be persistent. Many people do respond to a combination of Lamotrigine and Quetiapine (popularly called as Lami-quel). It takes time to act, but it is highly effective. Currently, I would suggest that instead ...  Read Full »

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