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Why do I feel weak even after taking vitamin B12 injections?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 67-year-old male with vitamin B12 deficiency and anemia. I was given six injections and a further four almost a month ago. I did feel that it was making a difference, but since stopping the injections, I have returned to fatigue, dizziness, muscle weakness, and mood swings.

My doctor is refusing to test my vitamin B12 but has checked the anemia, and my hemoglobin has moved from 114 to 117. I am not sure what scale is used. He also says he will not give more vitamin B12 injections until three months have passed.

Can you advise on my options and whether you agree with the treatment I am being offered?

Kindly help.

Answered by Dr. Prakash. H. M.

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and understood your concern.

The condition you described with your hemoglobin of 11.4 to 11.7 g/dL is good. It means the hemoglobin is improving and the bone marrow is functioning well. I am not sure about your vitamin B12 levels. You have already received ten injections, and it should have improved significantly. You possibly had a moderate to severe deficiency, which is why your doctor started injections.

With a hemoglobin of 11.7 g/dL, I would not think of any severe deficiency and would assume there are adequate stores. Only if it is falling and your hemogram shows a high MCV (mean corpuscular volume) would I consider vitamin B12 deficiency.

Look at MCV in the complete hemogram. If it is more than 100 fL, then vitamin B12 deficiency may still be present. If it is less than 100 fL, then it is adequate, and the red blood cells are being produced well.

Vitamin B12 is usually produced by gut bacteria in vegetarians. Green leafy vegetables, eggs, fish, and similar foods contain good amounts of vitamin B12. You can increase these in your diet and also use vitamin B12 supplements if necessary. Review your hemogram and check the MCV values.

Fatigue, dizziness, weakness, and mood swings are commonly due to anemia. However, your anemia has improved enough that symptoms should be less. If you are staying in a hilly or mountainous area, you may require higher hemoglobin levels. Otherwise, these levels should be adequate. Take more rest, as improvement in stamina will take time.

Vitamin B12 injections are not always necessary unless you have pernicious anemia, where orally taken vitamin B12 does not get absorbed. If you had pernicious anemia, your doctor would likely have informed you. So, do not worry and continue oral vitamin B12 as advised.

Repeat vitamin B12 evaluation is not always necessary. Improving hemoglobin levels is most important, and since it is improving, there is less cause for concern. For any future queries, if possible, attach your reports for a more detailed opinion.

I hope you are satisfied with my answer. For further queries, you can consult me at iCliniq.

Thank you.

Medically reviewed by iCliniq medical review team
Published At April 26, 2026
Reviewed At April 28, 2026

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

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Vitamin B12 Injection Companion

How it works

B12 injections refill your body's stores, but the parts of your body that depend on B12, your blood cells and your nerves, recover on different timelines. Here is what is happening inside, and what your doctor is watching.

1💊

What
B12 Does

2🩸

Why You
Feel It

3💉

How Shots
Work

4📊

Blood Tests
To Watch

5

Recovery
Timeline

If you finished a round of injections and feel worse again

Many people in this Q&A's situation, a few weeks after their last B12 shot, with fatigue and dizziness returning, see steady but slower recovery on the blood side and a longer wait on the nerve side. The next two sections explain why, and what to bring up at your next visit.

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

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