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Zolpidem - Uses, Dosage, Side Effects, Drug Warnings, and Precautions

Published on Dec 19, 2020 and last reviewed on Jun 30, 2022   -  5 min read


Zolpidem is a hypnotic drug. Learn about its uses, dosage, drug warnings, side effects, precautions, drug interactions, and more.

Zolpidem - Uses, Dosage, Side Effects, Drug Warnings, and Precautions


Zolpidem is a sedative drug that produces sleep in patients with insomnia. It is the best option for enhancing your sleep quality. The dosage might not be similar for men and women. It is not recommended for children. It is used alone or in combination with other drugs. This tablet can potentially damage your vision.

Drug Group:

Zolpidem is a drug belonging to a group of drugs called Imidazopyridine. The medication is usually prescribed for a short duration. It is a prescription drug, and it is not available over-the-counter drugs. This drug helps a person to get proper sleep at night. The dosage should be adjusted by the doctor.

What Is Zolpidem Used For?

Zolpidem is used in the treatment of the following:

Insomnia is the first condition to be treated by Zolpidem. This drug helps lots of sleep-deprived patients to have a good quality of sleep. The two major cycles of sleep are rapid eye movement sleep and non-rapid eye movement sleep. In both cycles of sleep, dreams and nightmares that are disturbing might occur. Research shows that when a dream occurs, it means that the person has not slept well that day. Continuous dreams and nightmares might lead to disruption in sleep and abnormal sleeping patterns. The reasons for insomnia could be depression, anxiety disorders, post-traumatic stress, and other health conditions. If some medications are causing you insomnia, then you should probably check with your doctor for help. It is not advisable to take some medications along with Zolpidem because it can react with those drugs and cause adverse reactions. So, it is ideal to find the cause of insomnia and then treat it with Zolpidem.

Parasomnia is the other type of sleep disorder that can be treated by Zolpidem. Parasomnia might include walking during sleep, talking during sleep, and having sex in the middle of sleep.

How Does Zolpidem Work?

Zolpidem is a drug that deals with a chemical called gamma-aminobutyric acid (GABA). This chemical is also an amino acid. But it acts as a neurotransmitter substance in the brain. The excitability of the neurons in the brain is essential for the transmission to take place. Gamma-aminobutyric acid acts by inhibiting the signals in the brain. In this way, certain signals and pathways are blocked. When gamma-aminobutyric acid gets attached to its respective receptors, then it gives a relaxed and calm feel for the body. When the whole body is relaxed, it provides a soothing feeling which puts the person to sleep. The levels of gamma-aminobutyric acid should always be maintained at the optimum levels. Any reduction in these levels of gamma-aminobutyric acid might cause other side effects such as seizures, mood disorders, panic disorders, and anxiety.

Onset Of Action:

The onset of action is very short. It takes only less than 30 minutes. The onset of action varies from person to person. In some people, the effect starts within 15 minutes.


This drug can cause a habit-forming tendency. It has been reported that patients who start taking this drug for sleep problems develop a certain degree of addiction. Some people find difficulties in sleeping after long term usage.

Expiry Date:

These drugs require a compulsory recommendation from doctors. The expiry date will be printed on the back of the pack.

What Is the Dosage of Zolpidem?

The dosage of Zolpidem varies according to gender.

Zolpidem dosage for adults:

How to Use Zolpidem?

Zolpidem is taken in the form of a tablet. To overcome the insomnia episodes, you should take the medications as prescribed by the doctor. It is better to take these drugs at night as they are sedatives. Consuming these drugs during morning hours might cause dizziness.

Missed Dose:

You cannot take the dose when you are reminded of it. If you miss a dose, try to take it before bed the next day. If you have skipped the dose for an extended period of time, it is not advisable to take it after that. You should get advice from your doctor before taking it again.

What Are the Drug Warnings and Precautions?

What Are the Side Effects of Zolpidem?

Zolpidem can cause severe or mild side effects. The following list contains some of the acute side effects that may occur while consuming Zolpidem. It does not include all possible side effects of Zolpidem. It is better to consult with a doctor or pharmacist for more information on Zolpidem's potential side effects or advice on how to handle a troubling side effect.

The common side effects of Zolpidem are:

If the above side effects are mild, then it may go away within a few days or with a couple of weeks. If they are more critical or do not go away, talk to your pharmacist or doctor.

The severe side effects are:

Call the doctor immediately if you have serious side effects that feel life-threatening or if you think you need a medical emergency. Serious side effects and their symptoms are:

What Are the Interactions of Zolpidem?

All the drugs would not be suitable for consumption, along with Zolpidem. So, if you already have a medical condition and you are taking medications for this, you should check with your doctor before taking Zolpidem. The common interactions of Zolpidem are:

  1. Escitalopram.

  2. Atorvastatin.

  3. Lorazepam.

  4. Esomeprazole.

  5. Melatonin.

  6. Metoprolol.

  7. Pregabalin.

  1. Glaucoma.

  2. Depression.

  3. Liver disease.

  4. Renal function.

  1. Consuming alcohol can damage the liver. Therefore, alcohol drinking habits should be stopped.

What Are the Common Brand or Trade Name of Zolpidem?

The common brand or trade names of Zolpidem are:

  1. Tablet Dactive 10 mg.

  2. Tablet Ambiz 10 mg.

  3. Tablet Getrest 10 mg.

Frequently Asked Questions


Is Zolpidem a Sleeping Pill?

Zolpidem acts like a drug that produces sleep. It helps patients with insomnia to get better sleep. It should not be used just like that to put a person to sleep. It should be taken only after the advice from the doctor.


Is Zolpidem Safe to Take?

Zolpidem has the ability to cause drug dependence or addiction. So, it is necessary to take it in mild doses in the initial stage. Taking heavy doses in the earlier stage can be dangerous for your health. It is always wise to follow the instructions given by your doctor for the usage of this drug.


How Quickly Does Zolpidem Work?

Zolpidem can start working within 15 minutes in some patients. This is the reason Zolpidem is always advised to be consumed at night. But the onset of action totally depends on the individual’s health condition. For some patients, it might work faster; for some patients, it might take time.


What Is Zolpidem Used For?

Zolpidem is used for the healing of sleeping patterns in insomnia patients and parasomnia patients. This can help patients who are suffering without sleep to get sound sleep. But one should be aware of the side effects. Consult your doctor before taking these drugs.


How Many Milligram of Zolpidem Is Safe?

The safe dosage for men is 10 mg and 5 mg for women in adults. The dose will be increased by your doctor if necessary. You should not self-medicate with this drug.


How Dangerous Is Zolpidem?

Some people use these drugs for an endorphin rush. Using this drug for such activities is considered a dangerous one. So, it is necessary that you get advice from your doctor to avoid the potential risks.


Does Zolpidem Relax You?

Yes, it provides a soothing feel for the body because it directly acts with the gamma-aminobutyric acid. This gamma-aminobutyric acid blocks certain receptors in the brain and thereby produces a relaxing effect.


Does Zolpidem Affect Memory?

Zolpidem causes short term memory loss in some patients. The other side effects are nausea, vomiting, headache, and drowsiness. Extreme drowsiness and loss of memory are known to occur in a few patients.


Can Zolpidem Be Taken Long Term?

When consuming Zolpidem for more extended periods, its side-effects can take its toll on the brain. Zolpidem can also cause psychological issues in long-term consumers, which includes
- Aggression.
- Anxiety.
- Confusion.
- Impaired memory.
- Hallucinations.
- Sense of dissociation in the body.
- Suicidal thoughts.
- Depression.


Can Zolpidem Cause Heart Problems?

No, Zolpidem will not cause heart problems. The patients having Zolpidem have a greater tendency to reduce the risk of heart disease. The stress-reducing capacity of these drugs might be the reason for a reduced percentage of heart problems.

Article Resources

Last reviewed at:
30 Jun 2022  -  5 min read




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