HomeAnswersOtolaryngology (E.N.T)acoustic traumaCan Prednisone therapy exacerbate symptoms of acoustic trauma?

Can acoustic trauma symptoms worsen with Prednisone treatment?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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Published At February 28, 2024
Reviewed AtFebruary 28, 2024

Patient's Query

Hello doctor,

I have visited this website previously.

Two months ago, I experienced an incident where a young child screamed directly into my left ear while I was holding her. The sound was extremely loud, causing vibrations in my eardrum. I have a history of Eustachian tube dysfunction in my left ear due to sinus or allergy issues, especially when flying.

The following day, I only felt slight fullness in my ear, but by the day after, I experienced heavy fullness, minor ringing, and ear pain. On the fifth day of symptoms, I began a Prednisone regimen starting at 60mg for seven days, then reducing to 40mg for three days, and finally 20mg for three days.

I am currently on the seventh day of Prednisone therapy, and it has been nearly one and a half weeks since the incident. However, a few concerning developments have occurred:

  1. The symptoms in my left ear have worsened. The ringing is almost constant, whereas before, it was intermittent. The ear fullness has not improved significantly and is particularly severe in the mornings.

  2. I am experiencing numerous side effects from the Prednisone therapy, which are impacting me significantly.

I am curious if it is typical for symptoms of acoustic trauma to worsen with Prednisone treatment. Additionally, based on your experience with other patients, is there hope for improvement in my case?

I have attached a hearing test conducted two months ago, which indicates hearing loss.

Kindly help me cope with this situation.

Thank you.

Hello,

Welcome to icliniq.com.

I can understand your concern.

The pure tone audiogram indicates noise-induced sensorineural hearing loss, albeit mild. Currently, the primary concern is tinnitus, which is commonly observed in patients with a history of acoustic trauma. Predicting the duration or severity of tinnitus is challenging. High-dose steroid therapy is currently the most effective treatment option. Additionally, ancillary treatments such as Betahistine and other agents like Caroverine (Caroverine hydrochloride), along with a short course of low-dose Benzodiazepine, may help reduce tinnitus severity. Over time, tinnitus is expected to improve, given the minimal hearing loss, which should not significantly impact function. If tinnitus persists, intratympanic steroid therapy may be considered.

Kindly consult a specialist, talk to them and take the medications with their consent.

I hope this information will help you.

Thank you.

Patient's Query

Hello doctor,

Thank you for your reply.

In your experience, have you observed variations in patient’s responses to steroid treatment? I am concerned because my symptoms worsened on the seventh day of treatment.

Additionally, do the ancillary treatments you mentioned also alleviate ear fullness? Kindly help.

Thank you.

Hello,

Welcome back to icliniq.com.

Do you experience any symptoms of vertigo or nausea? Patients do indeed exhibit varying responses to steroids. Regrettably, predicting individual responses is challenging. However, considering the level of hearing loss, functional impairment should be minimal. Additionally, these treatments can address all the mentioned symptoms.

I hope this information will help you.

Thank you.

Patient's Query

Hello doctor,

Thank you for your reply.

Yesterday, I experienced my first episode of vertigo. It was an entirely new experience for me. I felt fine one moment, then suddenly became dizzy and lightheaded. I decided to walk outside, and eventually, the symptoms improved. Currently, I haven't introduced any additional medications and am nearing the end of my tapered Prednisone course.

Despite this, I still have a clogged sensation in my left ear and ringing. Based on the history provided, what do you think could have triggered the sudden onset of vertigo? Is the sensation of a clogged ear related to my eustachian tube dysfunction? Kindly help.

Thank you.

Hello,

Welcome back to icliniq.com.

Acoustic trauma can cause any or all hearing loss, ear fullness, tinnitus, and vertigo. A loud noise may well cause some alteration in the way the neuroepithelium of the inner works or may produce changes in endolymph circulation and cause pressure changes in the inner ear. These all can cause a sense of ear fullness and vertigo. Clogged ears can be due to ETD (eustachian tube dysfunction) but this sensation of fullness may be due to noise trauma also.

I hope this information will help you.

Thank you.

Patient's Query

Hello doctor,

Thank you for your reply.

I want to ask the following questions:

  1. Is it normal to experience vertigo symptoms for the first time two and a half weeks after the acoustic trauma event?

  2. I also sometimes feel temporary relief when I pop my ear. Is this consistent with ear fullness from acoustic trauma?

  3. If there is one recommendation you have in terms of further treatment based on what I described, what would it be?

I am struggling with such a wide variety of new symptoms I have never experienced. Kindly help.

Thank you.

Hello,

Welcome back to icliniq.com.

I would not characterize it as normal, as there may have been some changes in the functioning of the inner ear. However, it is possible to experience late-onset vertigo, possibly due to the displacement of otoliths, which are responsible for maintaining posture. This could lead to positional vertigo developing after some time.

One suggestion would be to incorporate tablet Betahistine up to 48 mg daily, into your treatment regimen. Additionally, Labyrinthine sedatives like Prochlorperazine or Meclizine could be considered. Another option to explore is intratympanic steroids.

Kindly consult a specialist, talk to them and take the medications with their consent.

I hope this information will help you.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Syed Peerzada Tehmid Ul Haque
Dr. Syed Peerzada Tehmid Ul Haque

Otolaryngology (E.N.T)

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