What is the treatment plan for a 48-year-old women with grade 1 endometrial adenocarcinoma?

Q. What should be done for grade 1 endometrial adenocarcinoma in a 48-year-old?

Answered by
Dr. Kumar Varadarajan Senthil
and medically reviewed by Dr.Nithila A
This is a premium question & answer published on Aug 14, 2019

Hello doctor,

What is the treatment plan for 48-year-old women with grade 1 endometrial adenocarcinoma and right ovary with endometroid carcinoma well differentiated 4.5 cm?



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Please also provide me with the following details to provide a treatment plan.

1. Depth of myometrial invasion.

2. Lymphovascular invasion- is present or not?

3. Status of the lymph node.

4. Peritoneal or omental sampling is done or not?

5. Pre-operative MRI findings.

Thank you doctor,

1. Focal myometrial invasion present on the inner half (no deep invasion).

2. Lympho-vascular invasion is not present.

3. MRI showed only uterus cancer not spot in the ovary.



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1. Was any lymph nodes removed at the time of the operation? And if so their status.

2. If any omental biopsy or sampling was done at the time of surgery? If yes, the results, please.

Thank you doctor,

The surgical pathology report says,

1. Endometrial adenocarcinoma, endometrioid, FIGO grade1 focal myometrial invasion present (inner half) invasion of deep myometrial not identified T1a. Lymph- vascular invasion not identified. Uterine cervix with no evidence of malignancy or dysplasia. Background endometrium with atypical hyperplasia. The definite extrauterine extension is not identified. Small intramural leiomyoma and focal adenomyosis present TNM T1A, NX.

2. Right ovary with endometrial carcinoma, is well-differentiated measuring 4.5 cm in most significant linear dimension involvement of ovarian surface not identified. Lymphovascular invasion not identified. Benign unremarkable left ovary. Benign unremarkable fallopian tubes. No testing of lymph nodes.



Welcome back to icliniq.com.

Based on the histopathology report, no further oncological treatment is needed. But need a routine follow-up for every four to six months. I would suggest annual imaging with contrast CT scan of chest or abdomen or pelvis with biannual blood works such as complete blood count, creatinine, and Ca125.

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