Though my total bilirubin level comes down, ALT, AST, and ALP levels remain high. Why?
Patient's Query
Hello doctor,
I want to show my LFT report. I was suffering from jaundice. In my first test result total bilirubin was 11.2 mg/dL (D: 2.1, ID: 9.1), and the values of ALT, AST, and ALP are 53, 41, and 162 U/L, respectively. Hepatitis B was negative. In my second test results, the total bilirubin count has been reduced to 1.29 mg/dL (D: 0.73, ID: 0.56). But ALT, AST, and ALP values are 131, 150, and 267 U/L. Kindly explain if total bilirubin is brought down to 1.29 mg/dL, why ALT AST and ALP are increased? What does it mean? What medications are preferred?
Hello,
Welcome to icliniq.com.
I can understand your concern and the following is my opinion about your asked question. ALT (alanine transaminase) or SGPT (serum glutamic pyruvic transaminase) is the liver cells' enzyme. So, raised the level of which is suggestive of liver cell (hepatocyte) damage. Your SGPT is elevated to some extent, and conjugated bilirubin are elevated. So, hepatitis or stone in bile canaliculi might be the cause for your elevated SGPT and bilirubin. Hepatitis could be here in the form of viral hepatitis like hepatitis A or E or some other cause. You can be prescribed ursodeoxycholic acid tablet or syrup for your condition. Meanwhile, take low-fat foods and drink more fruit juice like apple juice and coconut water. Your investigations need to be done in the form of an ultrasound abdomen, viral hepatitis marker for primary workup. In hepatitis SGPT and SGOT levels can fluctuate. So do not worry about that. Repeat your SGPT after a few days.
Patient's Query
Thank you doctor,
Both hepatitis B and C are negative. So maybe stone in the duct could be a problem. Further, is there any major problem according to you?
Hello,
Welcome back to icliniq.com.
Your bilirubin level is decreased, so it does not suggest major problems. You had jaundice at that time. Hepatitis B is negative, but you can investigate with hepatitis A and E viral marker, which is not done until now. You can attach any other reports if available. Revert with repeat SGPT after a few days.
Same symptoms don't mean you have the same problem. Consult a doctor now!
Related Questions
ALT and AST are out of range. What does it mean?
Hepatitis C - Common Questions Answered
AST and ALT levels are high since the 11th week of pregnancy. Is it alarming?
Is asthma permanently curable?
Although urine tests are negative, why am I having pregnancy symptoms?
My hepatitis B result is positive. Is it acute or chronic?
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.