Ana Test

ANA (antinuclear antibody) test is done to diagnose autoimmune diseases like rheumatoid arthritis and lupus. This test looks for the presence of antinuclear antibodies, which are autoantibody that attacks the body during an autoimmune reaction.

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All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Could autoimmune disorder present with chronic fatigue, memory loss and hypothyroidism?

Query: Hi doctor, Before two years, I had some preexisting conditions. I had fibromyalgia, polyneuropathy, macular pucker in both the eyes, hypothyroidism, osteoarthritis, irritable bowel syndrome, diverticulitis, candidiasis, pelvic floor dyssynergia, and arterial hypertension. I had collagenosis and I g...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. It is impossible for me to give a single diagnosis after reading your history. You can have some form of autoimmune disorder for which autoimmune disease workup can be planned. ANA (antinuclear antibody) investigation can be done preliminarily to check for autoimmune di...  Read Full »

What does severe joint pain, stiffness and fatigue with positive ANA indicate?

Query: Hello doctor, I am a 25-year-old male. I have been seeing a rheumatologist with no diagnosis, but I have joint pain, blurry vision, and fatigue are getting worse. It feels like my body is shutting down. In terms of tests the only abnormal test I have are positive ANA but no specific antibodies that...  Read Full »


Dr. Nupoor Acharya

Rheumatologist

Answer: Hello, Welcome to icliniq.com. Your symptoms are non-specific and do not fit into a single diagnosis of arthritis. You have not mentioned your joint pains in detail. It will help me understand the pattern of arthritis. Which joints are involved? Do you have swelling, morning stiffness, backache,...  Read Full »

Why do I get pain in my fingers especially in the morning?

Query: Hello doctor, I have pain in finger of hands and foot in the morning when I wake up. After I do some exercise the pain reduces. What must I do? I am currently on T4 levothyroxine.  Read Full »


Dr. Divya Agarwal

Rheumatologist

Answer: Hi, Welcome to icliniq.com. I have gone through your reports (attachment removed to protect patient identity), it shows that you have a high ANA (antinuclear antibodies). These are antibodies related to arthritis. I suggest that the pain in your fingers and toes may be associated with the same. I...  Read Full »

Please give your opinion about my ANA report.

Query: Hi doctor, I have had a positive ANA for at least 12 years with no other positive tests for autoimmune disease. My other symptoms are fatigue and some joint pain in hands and knees. Recently, I had a positive ANA of 1:640 speckled pattern with a note saying dense fine speckled pattern is noted. DN...  Read Full »


Dr. Kusumakar Srivastava

Diabetologist, General Medicine Physician, Internal Medicine Physician, Rheumatologist

Answer: Hi, Welcome to icliniq.com. You are fine. Please do not worry as nearly all your reports are fine (attachment removed to protect patient identity) and you are taking correct medicines also. As per your ANA (antinuclear antibody) with dense speckled patters is noted, I must say that there are many fa...  Read Full »

Why are there positive ANA, chronic fatigue with lightheadedness?

Query: Hi doctor,I am a 23-year-old female. I have positive ANA, chronic fatigue, and lightheadedness. Also, inflammation markers are elevated. I currently take Adderall 20 mg twice a day, and Prozac 40 mg once in a day. And I also performed laboratory tests like CBC, LDH, and CMP.  Read Full »


Dr. Naval Mendiratta

Rheumatologist

Answer: Hi, Welcome to icliniq.com. Thank you for writing. I have gone through your query. There seem to be some doubts about the reports, and I would like to know the history in some more detail. As per the history: 1. Since how long have you been experiencing fatigue? Is it worse during the day or at...  Read Full »

Does positive ANA test in fallopian tube cancer indicate a concerning issue?

Query: Hello doctor, My mother was diagnosed with a fallopian tube carcinoma five years ago and is in remission since treatment ended. Since that time, her doctor has routinely followed very comprehensive labs to check for overall wellness. One of those lab tests has always been her ANA (antinuclear antib...  Read Full »


Dr. Divya Agarwal

Rheumatologist

Answer: Hi, Welcome to icliniq.com. This test has been repeated several times with variable results. It does not seem to hold much significance in your mother's case, as she never had symptoms related to any disease associated with ANA. ANA is not a screening test. It should be done only if there is sus...  Read Full »

Previously positive ANA turned negative. Is it safe to plan pregnancy now?

Query: Hello doctor,My daughter had a little girl four years ago. About three months postpartum, she fell down a flight of stairs injuring her back. At the same time, she had a very bad cold. When her back continued to give her pain after seeing the orthopedist, she went to a neurologist. Her blood work sh...  Read Full »


Dr. Naval Mendiratta

Rheumatologist

Answer: Hello, Welcome to icliniq.com. Yes, there have been cases where ANA once positive becomes negative towards the later part. Initially, it may have been induced by pregnancy or any infection but over course of time, it becomes negative. As for your friend, I would suggest we do ENA (extractable nucl...  Read Full »

Will early-stage lupus lead to cancer?

Query: Hi doctor, I started having joint pain a year ago in the neck, shoulder, wrist, and foot. I went to see my internist who ran an ANA, and it came back positive with a 1.116. Then saw a rheumatologist who took more tests and said I tested for early-stage lupus with a 29 in the anti-DNA antibody test....  Read Full »


Dr. Anshul Varshney

Criticalcare Physician, Diabetologist, General Medicine Physician, Internal Medicine Physician, Medical Gastroenterologist, Nephrologist, Pulmonologist, Rheumatologist

Answer: Hi, Welcome to icliniq.com. Do not worry; we are here to help you. The large joint pains are not significant for autoimmune (abnormal immune response) diseases. I need to know if you have: Any specific small joint pains. Any eye problems like uveitis (frequent reddening or itching of eyes). A...  Read Full »

Why do I have red bumps on my knuckles?

Query: Hi doctor,For as many years as I can remember I have these red bumps on my knuckles on the top of my hand. The funny thing is, every time when I am pregnant they disappear. Can you tell me what it could possibly be? I have eczema, but that does not go away during pregnancy.  Read Full »


Dr. Suvash Sahu

Cosmetologist, Dermatologist, Venereologist

Answer: Hi, Welcome to icliniq.com. I have seen your pictures and descriptions (attachment removed to protect patient identity). It looks like knuckle hyperpigmentation. It can occur in certain dermatological conditions like vitamin B12 deficiency, allergic contact dermatitis and SLE (systemic lup...  Read Full »

I feel numbness and fatigue with random body pain. Do they imply lupus?

Query: Hello doctor, I am an active 31-year-old male and I have been dealing with a number of issues related to numbness, fatigue, weakness, weak hands, shaking, burning mouth, and random pains in my body. I went to a neurologist to get a bunch of tests. I tested positive ANA specifically for DNA (DS) ant...  Read Full »


Dr. Rajiv Ranjan Kumar

Rheumatologist, General Medicine Physician, Internal Medicine Physician

Answer: Hi, Welcome to icliniq.com. The symptoms you have may occur due to various reasons commonly fibromyalgia or multivitamin deficiencies. The classical symptoms of lupus are fever, oral ulcers, photosensitivity rash, joint pain, swelling, kidney problems, alopecia, etc. ANA (antinuclear antibodies...  Read Full »

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Disclaimer: All health Q&As published on this website are not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.