Ana Test

ANA (antinuclear antibody) test is done to diagnose autoimmune diseases like rheumatoid arthritis and lupus. This test looks for the presence of antinuclear antibodies, which are autoantibody that attacks the body during an autoimmune reaction.

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Do I have a headache, skin rashes, petechiae, chills, hair loss, and lightheadedness due to an infection or autoimmune disease?

Query: Hello doctor,Over the past year, I have had polyclonal B cell activation, raised IgM, and positive ANA (antinuclear antibodies) with systemic flu-like symptoms. However, doctors do not comment on anything because I have worsening symptoms. I experience fatigue, Raynaud's disease, skin rashes, petech...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your investigations (attachments removed to protect the patient's identity), and your symptoms suggest connective tissue disease. ANA (antinuclear antibody) test is positive, and you have oral ulcers, skin rash, and hair loss. All of them are suggestiv...  Read Full »

What are long-term effects of arthritis affecting the neck and wrist?

Query: Hello doctor, I am having symptoms of arthritis in my neck and wrist for more than ten years, and it is getting worse now. I thought it could be due to the effect of wear and tear of my old car accident. And sometimes, I convince myself by saying that it is because of aging. I also had back-to-ba...  Read Full »


Dr. Nupoor Acharya

Answer: Hello, Welcome to icliniq.com. The symptoms you have described could be seen in lupus or other connective tissue diseases. Your ANA (antineutrophil antibody) is repeatedly positive. However, the ANA profile does not show any specific antibody. But that does not confirm that you cannot have a conne...  Read Full »

Does positive ANA and Scl 70 mean scleroderma?

Query: Hello doctor, My son has a positive ANA and Scl 70. I just do not get it. I am in shock as I am sure anyone else would be. Does this mean for sure he has scleroderma? He has no symptoms.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Positive ANA (anti-nuclear antibody) suggestive of some form of autoimmune disorder or connective tissue disorder. Anti-Scl (scleroderma) positivity suggestive of scleroderma. But provide me your report as an attachment for giving more comment as I want to know refer...  Read Full »

My AST and ALT levels are 92 and 143 respectively, and I am ANA positive. Should I be worried?

Query: Hi doctor, I am sharing my blood profile and ultrasound results details to get some insightful feedback. I am 29-year-old female with a weight of 130 kg and 5’7 height. I am currently on Levothyroxine and Sertraline. My AST levels were 92 U/L, and my ALT was 143 U/L. My physician has also suggeste...  Read Full »


Dr. Mashfika N Alam

Answer: Hi, Welcome to icliniq.com. I understand your concern. Could you specify how long you have been taking Levothyroxine? I know you are concerned about your medical condition, but Levothyroxine can also cause deranged liver enzymes as it undergoes hepatic metabolism. Since you have no symptoms like...  Read Full »

Can Hashimoto's thyroiditis result in high ANA titer?

Query: Hi doctor, I have had an autoimmune reaction for a year now. Symptoms include fatigue, joint and muscle pain, fever spikes (never above 100oF), 40 lbs weight gain in five months, trouble losing weight, swelling, random rashes, heart palpitations, brain fog, migraines, stomach aches, etc. I am curr...  Read Full »


Dr. Sayan Mukherjee

Answer: Hi, Welcome to icliniq.com. I understand your concern. Such a high tire ANA (antinuclear antibodies) with centromere positive and musculoskeletal and systemic complaints is usually associated with Sjogren's syndrome, MCTD (mixed connective tissue disease). Concerning your age, it is less likel...  Read Full »

My daughter has swollen lymph nodes and positive ANA. Please provide opinion.

Query: Hello doctor, My daughter, 15 years, has swollen lymph nodes. Biopsy is done. It is non-malignant. No tuberculosis. But ANA has come positive. I would like to share the reports and take your opinion.  Read Full »


Dr. Naval Mendiratta

Answer: Hello, Welcome to icliniq.com. There is a possibility of autoimmune disorder with underlying ANA and large lymph nodes. It is a good thing the malignancy is ruled out. But I would like to see the detailed biopsy report as well to be sure where we are heading. As for ANA positive, I would like to ...  Read Full »

Is it fine to take Prednisone and Azathioprine for autoimmune hepatitis?

Query: Hi doctor, I have been itching throughout my body, especially after eating, for about two years. I noticed fatigue and shortness of breath about 18 months ago. I stopped smoking before seven years. I stopped drinking before a year as my upper abdominal area started paining after drinking. Before fi...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. There are a few important facts I would want you to consider. We have to rule out other forms of hepatitis like viral hepatitis, amyloid or iron deposition, NASH (nonalcoholic steatohepatitis) and alcoholic liver disease. All three markers are non-specific;...  Read Full »

I have an enlarged lymph node on the side of my neck with a low fever and ANA 1:16. What might it be?

Query: Hi doctor, I have enlarged lymph nodes on the side of my neck and experienced a low fever on and off for four days. I tested positive for ANA (Antinuclear antibody) 1:16, speckled pattern. No sign of abnormality in my chest X-ray result. I do not have any other symptoms, such as skin rash or muscle ...  Read Full »


Dr. Sugreev Singh

Answer: Hi, Welcome to icliniq.com. Thank you for writing, and I understand your concern. When actually in large lymph nodes, it can be due to infection. Bacterial infection can lead to such swollen lymph nodes. But at the same time, positive ANA (Antinuclear antibody) indicates for them, so there might...  Read Full »

I have low TSH, normal T3 and T4, and positive ANA. Is there a chance of me having an autoimmune disease?

Query: Hello doctor, I checked my thyroid panel and got a very low TSH of 0.01 mlU/L and normal T3 and T4. I also did the arthritis panel, and my antinuclear antibody test came positive. I do not have hyperactive thyroid symptoms, except for low energy and muscle tightness. I take tablet Cyclobenzaprine 5 ...  Read Full »


Dr. Shaikh Sadaf

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. I would like to see the remaining tests you must have done along with these tests. Your thyroid status looks like subclinical hyperthyroidism. An associated antinuclear antibody positive autoimmune rheumatic disea...  Read Full »

I have constant muscle twitching in both calves with deranged ANA values. Kindly help.

Query: Hi doctor,I have had twitches in both calves for about nine weeks now. These twitches constantly happen when at rest without any pain, and the twitches are visible in both calves. Sometimes I experience cramps in my feet also. I consulted a doctor and did MRI, nerve conduction study, and an EMG. Eve...  Read Full »


Dr. Mohamad Ali Rida

Answer: Hello, Welcome to icliniq.com. ANA (antinuclear antibody) is a very delicate test and depends on the substrate used for testing. Some laboratories use primate substrate, and this yields a false-positive result. DFS 70 (dense fine speckled antibody) confirms that ANA might be related to an actual r...  Read Full »

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