Ana Test

ANA (antinuclear antibody) test is done to diagnose autoimmune diseases like rheumatoid arthritis and lupus. This test looks for the presence of antinuclear antibodies, which are autoantibody that attacks the body during an autoimmune reaction.

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I have low TSH, normal T3 and T4, and positive ANA. Is there a chance of me having an autoimmune disease?

Query: Hello doctor, I checked my thyroid panel and got a very low TSH of 0.01 mlU/L and normal T3 and T4. I also did the arthritis panel, and my antinuclear antibody test came positive. I do not have hyperactive thyroid symptoms, except for low energy and muscle tightness. I take tablet Cyclobenzaprine 5 ...  Read Full »


Dr. Shaikh Sadaf

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. I would like to see the remaining tests you must have done along with these tests. Your thyroid status looks like subclinical hyperthyroidism. An associated antinuclear antibody positive autoimmune rheumatic disea...  Read Full »

Is it fine to take Prednisone and Azathioprine for autoimmune hepatitis?

Query: Hi doctor, I have been itching throughout my body, especially after eating, for about two years. I noticed fatigue and shortness of breath about 18 months ago. I stopped smoking before seven years. I stopped drinking before a year as my upper abdominal area started paining after drinking. Before fi...  Read Full »


Dr. Sadaf Mustafa

Answer: Hi, Welcome to icliniq.com. There are a few important facts I would want you to consider. We have to rule out other forms of hepatitis like viral hepatitis, amyloid or iron deposition, NASH (nonalcoholic steatohepatitis) and alcoholic liver disease. All three markers are non-specific;...  Read Full »

I have constant muscle twitching in both calves with deranged ANA values. Kindly help.

Query: Hi doctor,I have had twitches in both calves for about nine weeks now. These twitches constantly happen when at rest without any pain, and the twitches are visible in both calves. Sometimes I experience cramps in my feet also. I consulted a doctor and did MRI, nerve conduction study, and an EMG. Eve...  Read Full »


Dr. Mohamad Ali Rida

Answer: Hello, Welcome to icliniq.com. ANA (antinuclear antibody) is a very delicate test and depends on the substrate used for testing. Some laboratories use primate substrate, and this yields a false-positive result. DFS 70 (dense fine speckled antibody) confirms that ANA might be related to an actual r...  Read Full »

I have positive antinuclear antibodies and have been diagnosed with mast cell activation syndrome (MCAS) and Hashimoto's disease. Kindly help.

Query: Hello doctor, I just received blood tests showing positive ANA tests and my doctor recommended for a rheumatologist look at my tests. The rheumatologists in my area have wait lists for six months. I was suffering from chronic fatigue, joint and nerve pain, a growing sensitivity to most foods, sensit...  Read Full »


Dr. Mohamad Ali Rida

Answer: Hello, Welcome to icliniq.com. ANA (antinuclear antibodies) is a general screening test for autoimmune diseases mainly lupus. Your anemia and photosensitivity raise the concern of possible lupus, especially at your age. However, this test is not enough for diagnosis. You need more tests that can be ...  Read Full »

How to cure my back pain which has been there for more than seven years?

Query: Hello doctor, I am a 29 year old female. I have been dealing with back pain for over seven years now. I have never been in any type of injury and had MRIs done of my brain, cervical, lumbar, and thoracic spine five years ago. They stated I had three bulging discs and an annular tear. My thoracic sp...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your post. You have not mentioned what you want to know and what your current problem is. You have degenerative disc disease involving both cervical and dorsal spines; however, there is no significant canal stenosis. I am sure you are not also symptomat...  Read Full »

Do I have a headache, skin rashes, petechiae, chills, hair loss, and lightheadedness due to an infection or autoimmune disease?

Query: Hello doctor,Over the past year, I have had polyclonal B cell activation, raised IgM, and positive ANA (antinuclear antibodies) with systemic flu-like symptoms. However, doctors do not comment on anything because I have worsening symptoms. I experience fatigue, Raynaud's disease, skin rashes, petech...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your investigations (attachments removed to protect the patient's identity), and your symptoms suggest connective tissue disease. ANA (antinuclear antibody) test is positive, and you have oral ulcers, skin rash, and hair loss. All of them are suggestiv...  Read Full »

I have an enlarged lymph node on the side of my neck with a low fever and ANA 1:16. What might it be?

Query: Hi doctor, I have enlarged lymph nodes on the side of my neck and experienced a low fever on and off for four days. I tested positive for ANA (Antinuclear antibody) 1:16, speckled pattern. No sign of abnormality in my chest x-ray result. I do not have any other symptoms, such as skin rash or muscle...  Read Full »


Dr. Sugreev Singh

Answer: Hi, Welcome to icliniq.com. Thank you for writing, and I understand your concern. When actually in large lymph nodes, it can be due to infection. Bacterial infection can lead to such swollen lymph nodes. But at the same time, positive ANA indicates for them, so there might be rheumatoid arthriti...  Read Full »

Can primary Raynaud alone result in elevated ANA in me?

Query: Hello doctor, I have Raynaud's phenomenon, can primary Raynaud's alone cause high ANA? I have underlying chronic urticaria syndrome. Recently, my skin has become even more sensitive than usual (rubbing against my bed has torn skin), there is sweating from my forehead even when not hot. I am currentl...  Read Full »


Dr. Mohamad Ali Rida

Answer: Hi, Welcome to icliniq.com. Usually, primary Raynaud's is not associated with any other disease. However, with your background of urticaria (autoimmune) and positive anti-nuclear antibodies (ANA), I would dig more towards secondary Raynaud's. For now, we can observe any vasculitis symptoms, includ...  Read Full »

What can cause increase in blood albumin?

Query: Hi doctor, My uncle has +3 albumin in his blood. He is not hypertensive and diabetic. What is the reason for the increase in albumin? What is the treatment? I have attached his reports.  Read Full »


Dr. Anshul Varshney

Answer: Hi, Welcome to icliniq.com. I have evaluated his report (attachment removed to protect patient identity), and his urine test shows the presence of RBC (red blood cells) and protein in his urine. This is serious and requires attention. The most common causes are diabetes and hypertension, so they ...  Read Full »

How to confirm that a person is suffering from Systemic Lupus Erythematosus(SLE) ?

Query: Hi doctor, How to confirm that a person is suffering from SLE (Systemic Lupus Erythematosus)?  Read Full »


Dr. Rakesh Karanwal

Answer: Hi, Welcome to icliniq.com. Get ANA test (Antinuclear antibodies) done to diagnose SLE. Though ANA is positive in other autoimmune diseases too, it is strongly positive in SLE. Once this test is found to be positive, it is correlated with signs and symptoms to confirm SLE. In case of doubt, other ...  Read Full »

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