Q. My diabetic mother has fever, body and joint pain and the ANA test is positive. What is the reason?

Answered by
Dr. Salah Saad Shoman
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Oct 22, 2019

Hello doctor,

My mother is 65 years old. She is a diabetic. For the past one month, she had fever, body pain, and joint pain. After a while, her leg started swelling, and slowly the blood platelet count came to 28000. She got admitted to the hospital and was on Xone antibiotics and Dolo 650 with trips. Leg swelling slowly reduced and the platelet count reached 125000.

Four months before, she had a leg swelling and it got cured after taking some medicines prescribed by a doctor.

Basic creatinine, dengue, blood test, and scan were done. Light swelling in the liver and spleen is seen.

Dengue and other basic reports showed negative. Today we received a report positive (ANA), Pattern: Nuclear fine granular (strongly positive). This may be associated with SJS, SLE, neonatal LE, Polymyositis, dermatomyositis, progressive systemic sclerosis. Can you please advise.

Dr. Salah Saad Shoman

General Medicine Internal Medicine


Welcome to icliniq.com.

I have gone through your question and understood your concerns. Autoimmune attacks that lead to decreased platelet count (thrombocytopenia) are mostly associated with systemic lupus syndrome or can be associated with rheumatoid arthritis in case there is an associated joint involvement. I would recommend that you get an anti-lupus antibody testing and rheumatoid factor testing to confirm or exclude the diagnosis.

I hope this helps.

Was this answer helpful?


Thank you doctor,

Can you please advise whether it is curable and the reason for getting affected?

Dr. Salah Saad Shoman

General Medicine Internal Medicine


Welcome back to icliniq.com.

There are many theories for autoimmune diseases, including genetic predisposition and environmental triggers. However, none were conclusive. Autoimmune disorders are chronic diseases that can be put into remission by medications, while relapse attacks can occur during stress periods at any time.

Was this answer helpful?


Ask a QueryAsk a Query Consult by PhoneConsult by Phone Video ChatVideo Chat
Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

Related Questions & Answers

Is lupus causing all my symptoms?

Query: Hi doctor, I am a 44 year old female, and I have been diagnosed with rheumatoid arthritis, systemic lupus, and Sjogren's syndrome, with symptoms dating back to as young as six years old. I have also been diagnosed with pulmonary hypertension, thyroiditis, Raynaud disease, right-sided heart enlargeme...  Read Full »

Test for multiple query thread

.. woman of heart it total other. By in entirely securing suitable graceful at families improved. Zealously few furniture repulsive was agreeable consisted difficult. Collected breakfast estimable questions in to favourite it. Known he place worth words i …  Read Full »

Testicular Pain

Article Overview: Read about all the possible causes and symptoms of testicular pain. Also, learn about home remedies and treatment options. Read Article

Dr. Sneha Kannan

Testicle Anatomy Testes or testicles are male reproductive glands which produce sperm and the hormone testosterone. Males have two testicles within the scrotum, which is the extension of the abdominal wall. The testes are covered by a membrane called tunica albuginea, and the insides are made of fi...  Read Article



Ask your health query to a doctor online?

Ask an Internal Medicine Physician Now

* guaranteed answer within 4 hours.
Enter Your Health Query
You can upload files and images in the next step.



Disclaimer: All health Q&As published on this website is not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.