Common "Anticoagulant Therapy" queries answered by top doctors | iCliniq

Anticoagulant Therapy

Anticoagulants are substances that reduce or prevents coagulation of blood by prolonging the clotting time. It suppresses the functions of various clotting factors that are present in the blood. These drugs prevent the formation of blood clots in the arteries or veins. Anticoagulant therapy is commonly used in the treatment of VTE (venous thromboembolism). For treating pulmonary embolism and deep vein thrombosis, low molecular weight Heparin is used.

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I have been diagnosed with atrial fibrillation. Will Apixaban help?

Query: Hello doctor, I have been diagnosed with atrial fibrillation and prescribed Apixaban as an anticoagulant. Can you provide insights into how Apixaban works, and its role in managing atrial fibrillation? Additionally, are there any specific considerations or interactions with other medications, such ...  Read Full »

Dr. Dheeraj Kela

Answer: Hello, Welcome to I understand your concern. Factor Xa (activated form of the coagulation factor X) inhibitor inhibits platelet activation by selectively and reversibly blocking the active site of factor Xa without requiring a cofactor (coagulation factor) (eg, antithrombin III) for ac...  Read Full »

Please comment on the treatment and Doppler result of my mother for DVT.

Query: Hello doctor, My mother is suffering from DVT which was diagnosed just yesterday. I want a second opinion on her treatment and Doppler results. The doctor said that there is no need to admit her in the hospital and he prescribed Rivaroxaban 15 mg twice daily for 21 days along with Ibuprofen 400 mg. ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I can understand your concern. The following are the answers of your asked questions. Yes, your mother has been put on the best anticoagulant medication. Rivaroxaban and Apixaban are the best anticoagulant oral drugs. Enoxaprin is injectable anticoagulant drug to treat...  Read Full »

I am diagnosed with DVT and under Xarelto. Should I continue it for three months or six months?

Query: Hello doctor, I have diagnosed with DVT before four months and currently on Xarelto 20 mg once a day. My hematologist has advised me to take six months of Xarelto. However, the literature says three months is enough. My all test results like protein C deficiency, protein S, factor 5, and prothrombi...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to the I should appreciate your awareness of health. For venous thrombosis, anticoagulant should be taken for at least three months. However, when the risk of thrombosis is high then duration can be extended for the next additional three months. So the clinical correlatio...  Read Full »

I have undergone heart valve replacement and taking tablet Acitrom. Can I become pregnant?

Query: Hello doctor,I am a heart patient. I had two open-heart surgery for my valve replacement. I have a mechanical valve, and I need to take anticoagulants daily. At present I am on Acitrom 2 mg. I need to ask whether I can become pregnant after all these complications. Is it possible to become a mother ...  Read Full »

Dr. Muhammad Zohaib Siddiq

Answer: Hello, Welcome to Acitrom (Nicoumalone) is not safe in pregnancy. You may have to switch to low molecular weight Heparin subcutaneous injection twice daily. Anti-Xa levels must be checked after four to six hours of injection, and the target anti-Xa levels are 0.8 - 1.2 U/mL. The drug ...  Read Full »

Does my brother need renal protection medication because his creatinine level is 1.27, and he is on blood thinners and other cardiac medications?

Query: Hello doctor, My brother has a tingling sensation on his left side; he was hospitalized, and extensive testing was performed; nevertheless, no abnormalities were discovered. He was kept on blood thinners and other medications. Again, he complains about having difficulty walking, particularly with h...  Read Full »

Dr. Manzoor Ahmad Parry

Answer: Hello, Welcome to I read your query and can understand your concern. I have reviewed your history, case review, and investigations. Your cousin has a history of stroke. I have certain queries 1. What is blood pressure? 2. Does your cousin have a heart problem? Revert with the answer ...  Read Full »

Can anticoagulants be taken after knee surgery? Kindly help.

Query: Hello doctor, An 80-year-old man underwent a recent septic arthritic joint surgery and was hospitalized for 20 days. The medications prescribed were Levothyroxine 150 mg, Atorvastatin 20 mg, Ramipril 10mg, Bendroflumethiazide 2.5 mg, Metformin 500 mg twice daily, Tamsulosin 400 mg, and Lansoprazole ...  Read Full »

Dr. Sapkal Ganeshrao Patilba

Answer: Hi, Welcome to I have gone through the details you provided. The patient has had recent joint surgery. He has ischemic heart disease. But you have not mentioned angioplasty, bypass, or any blockages. If the patient has knee or hip joint surgery, he will need anticoagulant medication. ...  Read Full »

Is it dangerous to get pregnant with a history of pulmonary embolism?

Query: Hi doctor, When I was 15 years old, I had a bilateral pulmonary embolism with no known causation. I was wondering about my options for pregnancy in the future, rather, if it would be an option. I am currently taking Apixaban twice daily, and I am unsure of when I will stop taking it. My clots have ...  Read Full »

Dr. Poonguzhali Liston

Answer: Hi, Welcome to Happy to hear that you are doing well and it is very wise to be concerned about your future pregnancy. So let me outline a few things for you. Pregnancy itself is a state in which blood clots more than in a non-pregnant person. This is due to an increase in progesteron...  Read Full »

Do blood thinners and icing therapy need to be taken after my knee replacement surgery?

Query: Hi doctor, I have a knee replacement soon, and I have interstitial lung disease caused by autoimmune dermatomyositis. I am in remission and doing good. After my knee replacement, I asked my doctor whether I would need to take blood thinners or aspirin. She said I would get a compression sleeve to us...  Read Full »

Dr. Mrinal Prakash

Answer: Hi, Welcome to Yes, we usually give blood thinner in the post-operative management of total knee replacement. As far as my knowledge is concerned, these blood thinners are not contraindicated in dermatomyositis (unless a heart condition is associated). Ice can also be applied to the ba...  Read Full »

I am COVID positive, and my resting heart rate is 100. Shall I take tablet Xarelto now?

Query: Hello doctor, I am a 35-year-old male. My height is 5.7 feet, and my weight is 163 lbs. I am tested positive for COVID-19 today. My resting heart rate is 100, and I am fine without any scaring symptoms. My father died unexpectedly from a pulmonary embolism at the age of 33, and my three siblings h...  Read Full »

Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to Your heart rate seems to be linked to the anxiety of being tested positive for COVID-19 (Coronavirus disease-2019). Only a small number of patients get severe problems with this disease. And after vaccination, the complications become further smaller. Vaccinated people ...  Read Full »

Does positive factor V cause heavy bleeding and blood clots?

Query: Hi doctor,My factor V Leiden showed a positive outcome before three months. I got a Depo birth control shot before three months. I have heavy bleeding and blood clots now. Please suggest.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You have factor V Leiden showing a positive result. So you are at high risk for developing blood clots in various organs of the body especially in the lungs and legs as pulmonary embolism and deep vein thrombosis. If you have major clots occurring in the future, then bl...  Read Full »

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