Anticoagulant Therapy

Anticoagulants are substances that reduce or prevents coagulation of blood by prolonging the clotting time. It suppresses the functions of various clotting factors that are present in the blood. These drugs prevent the formation of blood clots in the arteries or veins. Anticoagulant therapy is commonly used in the treatment of VTE (venous thromboembolism). For treating pulmonary embolism and deep vein thrombosis, low molecular weight Heparin is used.

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Does positive factor V cause heavy bleeding and blood clots?

Query: Hi doctor,My factor V Leiden showed a positive outcome before three months. I got a Depo birth control shot before three months. I have heavy bleeding and blood clots now. Please suggest.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You have factor V Leiden showing a positive result. So you are at high risk for developing blood clots in various organs of the body especially in the lungs and leg as pulmonary embolism and deep vein thrombosis. If you have major clots occurring in the future, then blo...  Read Full »

How to treat hematoma present in my thigh?

Query: Hi doctor, Before five months, I had surgery for thigh hematoma. Now, the same problem started again. It is increasing in size and painful. Also, there is swelling. Please see the photo attached here.  Read Full »

Dr. Erioli Braholli

Answer: Hello, Welcome to 1. Hematomas are solved conservatively and only in severe cases when they give compression of an organ and are resolved surgically. This is not a big one (attachment removed to protect patient identity). 2. First, you have to find out the cause of hematoma if it is not...  Read Full »

Is it dangerous to get pregnant with a history of pulmonary embolism?

Query: Hi doctor, When I was 15 years old, I had a bilateral pulmonary embolism with no known causation. I was wondering about my options for pregnancy in the future, rather, if it would be an option. I am currently taking Apixaban twice daily, and I am unsure of when I will stop taking it. My clots have ...  Read Full »

Dr. Poonguzhali Liston

Answer: Hi, Welcome to Happy to hear that you are doing well and it is very wise to be concerned about your future pregnancy. So let me outline a few things for you. Pregnancy itself is a state in which blood clots more than in a non-pregnant person. This is due to an increase in progestero...  Read Full »

What is the treatment for mitral stenosis?

Query: Hello doctor, I am 30-years-old male. I have a mitral valve problem, and it is moderate mitral stenosis. What remedy do you advise? If I did the valvuloplasty surgery will there be any other problem? If there is a problem, is there a possibility to do the valvuloplasty again? I am afraid. Please rel...  Read Full »

Dr. Ilir Sharka

Answer: Hello, Welcome to There are specific criteria for surgery in case of mitral valve stenosis. Surgery does not resolve the problem and you may have to stay on anticoagulation therapy for your entire life. It can help improve your physical performance and avoid pulmonary edema (shortness...  Read Full »

Please comment on the treatment and Doppler result of my mother for DVT.

Query: Hello doctor, My mother is suffering from DVT which was diagnosed just yesterday. I want a second opinion on her treatment and Doppler results. The doctor said that there is no need to admit her in the hospital and he prescribed Rivaroxaban 15 mg twice daily for 21 days along with Ibuprofen 400 mg. ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I can understand your concern. The following are the answers of your asked questions. Yes, your mother has been put on the best anticoagulant medication. Rivaroxaban and Apixaban are the best anticoagulant oral drugs. Enoxaprin is injectable anticoagulant drug to treat...  Read Full »

What do positive lupus anticoagulants indicate in the first test of antiphospholipid syndrome?

Query: Hi doctor,I have recently been told my first test of antiphospholipid syndrome shows positive lupus anticoagulants. What does that mean for someone with no symptoms? I took Articaine and Phenphedrine the day before the test. Can an overdose cause the test to be faulty? I had four miscarriages so far...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You have a history of four recurrent miscarriage and cause for that seems to be an antiphospholipid syndrome. Because of thrombosis secondary to antiphospholipid syndrome, miscarriage occurred. If you are on anticoagulant medication, then it could be a false result...  Read Full »

Do blood thinners and icing therapy need to be taken after my knee replacement surgery?

Query: Hi doctor, I have a knee replacement soon, and I have interstitial lung disease caused by autoimmune dermatomyositis. I am in remission and doing good. After my knee replacement, I asked my doctor whether I would need to take blood thinners or aspirin. She said I would get a compression sleeve to us...  Read Full »

Dr. Mrinal Prakash

Answer: Hi, Welcome to Yes, we usually give blood thinner in the post-operative management of total knee replacement. As far as my knowledge is concerned, these blood thinners are not contraindicated in dermatomyositis (unless a heart condition is associated). Ice can also be applied to the ba...  Read Full »

Should an 80-year-old man with heart problems who underwent knee joint surgery be put on anticoagulants?

Query: Hello doctor, An 80-year-old man underwent a recent septic arthritic joint surgery and was hospitalized for 20 days. The medications prescribed were Levothyroxine 150 mg, Atorvastatin 20 mg, Ramipril 10mg, Bendroflumethiazide 2.5 mg, Metformin 500 mg twice daily, Tamsulosin 400 mg, and Lansoprazole ...  Read Full »

Dr. Sapkal Ganeshrao Patilba

Answer: Hi, Welcome to I have gone through the details you provided. The patient has had recent joint surgery. He has ischemic heart disease. But you have not mentioned angioplasty, bypass, or any blockages. If the patient has knee or hip joint surgery, he will need anticoagulant medication. Al...  Read Full »

I am COVID positive, and my resting heart rate is 100. Shall I take tablet Xarelto now?

Query: Hello doctor,I am a 35-year-old male. My height is 175 cm, and my weight is 74 kg. I am tested positive for COVID-19 today. My resting heart rate is 100, and I am fine without any scaring symptoms.My father died unexpectedly from a pulmonary embolism at the age of 33, and my three siblings have had ...  Read Full »

Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to Your heart rate seems to be linked to the anxiety of being tested positive for COVID-19 (Coronavirus Disease-2019). Only a small number of patients get severe problems with this disease. And after vaccination, the complications become further smaller. Vaccinated peo...  Read Full »

If D-dimer is high, can a patient with a history of hemorrhage take anticoagulants?

Query: Hi doctor, I am asking for my dad. He is 75-year-old, has diabetes for 30 years, no high BP, but has had MI, CABG 14 years back (attached the summary). He was diagnosed with COVID on the fourteenth of this month, mild case, no fever, just cough. His CT has 2/25. He was monitored and discharged on t...  Read Full »

Dr. Prashant Valecha

Answer: Hi, Welcome to I have gone through your father's reports and health summary (attachments removed to protect the patient's identity). I found that two reports of D-dimer are in different units, one in nanogram (ng) and one in microgram (ug). Both reports are normal. For prevention, I s...  Read Full »

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