HomeAnswersInternal MedicineantidepressantsMy husband has side effects from his medicines. Please help.

Can a patient taking antidepressants and painkillers develop life-threatening complications?


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At January 27, 2023
Reviewed AtJanuary 12, 2024

Patient's Query

Hello doctor,

I am worried about my husband as he may be harming himself. Due to an abdominal mass, doctors prescribed some pain medications on top of his Prozac for pain. Over six months, the mass shrunk, and he is back to work and still taking all of these medications: Buspar 15 mg, one tablet three times daily; Prozac 40 mg two tablets every morning, Atarax 25 mg one tablet twice daily. Hydrocodone 10 mg, two tablets daily, and a tablet of Desyrel at bedtime, drinking beer and mixed drinks, and using CBD oil on his aches. I am concerned, as he has a driving job and already seems quite irrational and paranoid when he gets drunk. He says really stupid things and lacks memory. Is this a life-threatening mix of prescription drugs? Kindly help.


Welcome to icliniq.com.

If he does not need pain medications, he should get rid of these, especially the tablet Hydrocodone (Codeine). Also, he is taking too many antidepressants that can not only risk his driving skills and also puts him at high risk of serotonin syndrome. Tablet Prozac (Fluoxetine hydrochloride) and Nortryplyline (colloidal Silicon dioxide, Magnesium stearate, pregelatinized starch, and Sodium lauryl sulfate) are about the same call drugs, and the tablet Atarax (Hydroxyzine hydrochloride) also makes drowsy. But I suggest stopping all at once as he may have withdrawal effects; discuss with his primary doctor and decrease doses one by one to stop all unnecessary medications.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Hafiz Muhammad Hassan Shoukat
Dr. Hafiz Muhammad Hassan Shoukat

Internal Medicine

Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Read answers about:


Ask your health query to a doctor online

Internal Medicine

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy