Q. I have constant cramps and pain in both buttocks which get down to legs and calf. Please help.

Answered by
Dr. Anshul Varshney
and medically reviewed by Dr. Vinodhini. J
This is a premium question & answer published on Mar 12, 2020

Hello doctor,

I have had permanent cramps and a constant ache in both buttocks. I have pain down the back of the legs in the calf and when I walk it feels like it is about to cramp and I get pain in front of the thigh. I have a constant aching feel. When I press my skin on both thighs it feels sore. I had it for over two months. I have pain on both sides of my thighs and legs regardless of if I am sitting or resting.

I got admitted to the hospital for two weeks and they did an MRI scan on my spine and found nothing. They did a lumbar puncture and found nothing. They also did a nerve examination and nothing was found. I am currently on Gabapentin, Codeine, and Paracetamol.



Welcome to

It looks like a nerve compression to me. If all investigations are normal, it does not mean it cannot be nerve compression. It could be meralgia paresthesia or neuralgia. I would recommend you to take Vitamin B12 shots.

Also, discuss with your doctor to prescribe you a combination of Pregabalin along With Nortryptilline in the night. This may take a few weeks to months to recover.

I hope this helps.

Thank you doctor,

With those medications do you think it is appropriate for my age as I am only 26? With the shots, would it be an injection? Also, I forgot to mention that I was given Ciprofloxacin for a UTI early. Could this be a long term side effect as I have read up many things on it? Would you also recommend acupunture?



Welcome back to

The medicines I have mentioned can be safely used at your age. Injection shots would be more useful than oral vitamin B12. Acupuncture you can give a try, it may help you. You can try acupuncture and all as a side treatment and not as the first line of treatment.

Have you got your thyroid profile, Vitamin B12, and Vitamin D levels?

Thank you doctor,

Please find my attached blood tests. I am not sure if this shows vitamin D, B12 or thyroid.



Welcome back to

Based on available reports (attachment removed to protect patient identity) and your symptoms, it simply looks neuralgia to me. Somehow, I am highly convinced that you would get relief with Pregabalin and Nortriptyline. In case you have taken it and no relief we would talk about further options.

I hope this helps.

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