Hi doctor,
I am beta thalassemia minor. If I go for a relationship DNA test with my son, will the DNA report be false due to this?
Hi,
Welcome to icliniq.com.
Based on your query, my opinion is as follows:
For further information consult a hematologist online --> https://www.icliniq.com/ask-a-doctor-online/hematologist
Thank you doctor,
I have a few more doubts. Kindly clarify. If I want to go for a relationship DNA test with my son, will the test be done from white blood cells and not from RBC? Is relationship DNA test always from WBC? For a beta thalassemia carrier, chromosome number 11 is affected and beta globulin of hemoglobin does not perform properly. If RBCs do not have DNA then how chromosome is coming into the picture? If I go for a DNA test then the allele size of me and my son's will be compared. In case of beta thalassemia minor the sizes of RBCs are smaller. Hence, will the allele sizes will also be smaller? I do not know whether my son is a carrier of beta thalassemia like me or not. In both the cases, is there any chance that the allele size will be affected and I will not get a true DNA test report to establish biological relationship with my son? In case of beta thalassemia carrier only the red blood cells get affected? Would DNA of RBC and WBC match? Can I go for a relationship DNA test being a beta thalassemia carrier? Will the test result appear correct whether my son is a carrier or not? Please clarify.
Hi,
Welcome back to icliniq.com.
Based on your query, my opinion is as follows:
For further doubts consult a hematologist online --> https://www.icliniq.com/ask-a-doctor-online/hematologist
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