Beta Thalesemia Minor

Beta thalassemia minor, otherwise called beta thalassemia trait, occurs when one of the beta-globin genes is mutated. Patients with this condition do not need any treatment as the symptoms are very mild. The abnormalities they have are mild anemia and smaller red blood cells.

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Is it too risky for me to marry someone with sickle cell trait if I have beta thalassemia trait?

Query: Hi doctor, I have beta thalassemia plus trait (AT+) and want to marry a man with sickle trait (AS). Please see the attached file of my beta thalassemia DNA genetics. Please give me the possibilities of our baby. I know there is a 25 % chance that the baby might have sickle beta plus¬†thalassemia (ST...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. I have seen the reports (attachment removed to protect patient identity). Thalassemia and sickle cell anemia are autosomal recessive disorders. In your case, the child can be thalassemia sickle cell carrier (heterozygous). The presentation will be mild to moderate...  Read Full »

Is beta thalassemia trait a serious case?

Query: Hello doctor, Is beta thalassemia trait a serious case?  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Let me explain you about beta thalassemia trait. It is good that you are aware of using online health portal. Beta thalassemia trait is the heterozygous condition and the patient can live a normal life. If nutrition is not maintained properly and if any unusual excess b...  Read Full »

I have anemia symptoms with beta thalessemia minor. Is it due to lack of iron?

Query: Hello doctor, I have minor beta thalassemia which I got from my mother, but unlike her (asymptomatic), I have anemia symptoms like paleness, shortness of breath after the least effort, feeling tired all the time, broken nails and I want to know if it could be due to lack of iron? Could people with ...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. I have reviewed your query and here is my advise. Yes, your symptoms point towards iron deficiency anemia. In beta thalassemia minor patient usually feels more fatigue on exertion as compared to normal people without thalassemia. However do not worry regarding thalasse...  Read Full »

Why is the Hb reducing in beta thalassemia minor patient who is pregnant?

Query: Hi doctor,My wife is pregnant with twins, 24 weeks now. Her Hb levels never in life had gone above 10. At the start of pregnancy, it was 8.5 but now it has touched 7.7. We did serum ferritin test and her level was 50 (normal) which I guess means no iron deficiency. She is a beta thalassemia minor as...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Thalassemia minor is hemoglobinopathy and so hemoglobin level can never be above 12 in such patient. In pregnancy, plasma is increased and so hemodilution can lead to more fall in hemoglobin level in CBC. Orofer XT like Iron tablet can be prescribed for such case. It wo...  Read Full »

I have thalassemia minor. How to increase hemoglobin and decrease ferritin levels?

Query: Hi doctor, I am a 76 year old male, who is 170 cm tall and weigh 68 kg. Presently I have anemia, and my hemoglobin is 9.6 g/dL. I also have high serum ferritin level of 1900 ng/mL. I have this problem for some time. Many years ago, I was diagnosed with thalassemia minor. I was feeling tired, and I h...  Read Full »


Dr. Saravan Pramod Settipalli

General Medicine Physician, Internal Medicine Physician, Family Physician

Answer: Hi, Welcome to icliniq.com. I have seen all your reports (attachment removed to protect patient identity). Thalassemia is an inherited blood disorder characterized by abnormal hemoglobin production. I do not have to explain you much about thalassemia as your doctor might have told you the details...  Read Full »

Can same blood group of parents cause any problem to baby?

Query: Hello doctor, Me and my wife blood group are same A positive. And my wife is five months pregnant. I want to know that is there any problem with our baby?  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. The same blood group not at all lead to any problem in conception. Same blood group people can marry and can produce a normal child. So as far as same blood group concerned do not worry about that. But as a doctor I will advise you to check your wife thalassemia mino...  Read Full »

How can I correct my pale look due to minor beta thalassemia?

Query: Hi doctor, I am a 22-year-old female and I have a minor beta thalassemia (heterozygous) which is supposed to be asymptomatic but I am very pale. This makes me extremely insecure especially when people keep pointing it out. Every day I get at least two people asking me what is wrong with me and why ...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. In thalassemia minor patient, Hb (hemoglobin) usually remains around 10-11 gm/dl. It is hemolytic anemia and so extramedullary erythropoiesis occurs in the bone marrow (attachment removed to protect patient identity). So, the mandible is also affected and become prom...  Read Full »

Will beta thalassemia minor affect the relationship DNA test?

Query: Hi doctor, I am beta thalassemia minor. If I go for a relationship DNA test with my son, will the DNA report be false due to this?  Read Full »


Dr. Prakash H Muddegowda

Geriatrician, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: No, relationship DNA test will not be affected. It is autosomal related. He may or may not be a carrier. DNA test will look at multiple patterns. If you want, you can go for DNA test. Being affected from thalassemia is not go...  Read Full »

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