Beta Thalesemia Minor

Beta thalassemia minor, otherwise called beta thalassemia trait, occurs when one of the beta-globin genes is mutated. Patients with this condition do not need any treatment as the symptoms are very mild. The abnormalities they have are mild anemia and smaller red blood cells.

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How can I correct my pale look due to minor beta thalassemia?

Query: Hi doctor, I am a 22-year-old female and I have a minor beta thalassemia (heterozygous) which is supposed to be asymptomatic but I am very pale. This makes me extremely insecure especially when people keep pointing it out. Every day I get at least two people asking me what is wrong with me and why d...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to In thalassemia minor patient, Hb (hemoglobin) usually remains around 10 to 11 gm/dl. It is hemolytic anemia and so extramedullary erythropoiesis occurs in the bone marrow (attachment removed to protect patient identity). So, the mandible is also affected and become p...  Read Full »

Can same blood group of parents cause any problem to baby?

Query: Hello doctor,My wife and I had the same blood groups as A positive. And my wife is five months pregnant. I want to know, is there any problem with our baby?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to The same blood group not at all lead to any problem in conception. Same blood group people can marry and can produce a normal child. So as far as same blood group concerned do not worry about that. But as a doctor I will advise you to check your wife thalassemia mino...  Read Full »

My husband and I have the same blood group B negative. Will this affect our future progeny in any way?

Query: Hello doctor, My husband and I have the same blood group that is B negative. If both partners have the same blood group, does it negatively impact the future progeny? Also, what other factors (other systems than ABO and Rhesus) must be considered before proceeding further? Please answer.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I went through your query and understood your concern. The B blood group is from the ABO blood grouping system; the negative is the Rh blood grouping system. You have a similar blood group, but this will not be a problem. You can get married. I suggest you both get ...  Read Full »

Does the relationship DNA test get affected by beta-thalassemia minor?

Query: Hi doctor, I am beta thalassemia minor. If I go for a relationship DNA test with my son, will the DNA report be false due to this?  Read Full »

Dr. Prakash H. M

Answer: Hi, Welcome to Based on your query, my opinion is as follows: No, a relationship DNA test will not be affected. It is autosomal related. He may or may not be a carrier. A DNA test will look at multiple patterns. If you want, you can go for a DNA test. Being affected by thalassemia...  Read Full »

Is beta thalassemia trait a serious case?

Query: Hello doctor, Is beta thalassemia trait a serious case?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to Let me explain to you about the beta thalassemia trait. It is good that you are aware of using online health portals. Beta thalassemia trait is a heterozygous condition and the patient can live a normal life. If nutrition is not maintained properly and if any unusual ...  Read Full »

I have anemia symptoms with beta thalessemia minor. Is it due to lack of iron?

Query: Hello doctor, Thank you for the reply, I have minor beta thalassemia which I got from my mother, but unlike her (asymptomatic), I have anemia symptoms like paleness, shortness of breath after the least effort, feeling tired all the time, broken nails and I want to know if it could be due to lack of ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I have reviewed your query and here is my advice. Yes, your symptoms point towards iron deficiency anemia. In beta thalassemia minor patient usually feels more fatigue on exertion as compared to normal people without thalassemia. However do not worry about thalassemia ...  Read Full »

Why is the Hb reducing in beta thalassemia minor patient who is pregnant?

Query: Hi doctor, My wife is pregnant with twins, 24 weeks now. Her Hb levels never in her life had gone above 10. At the start of pregnancy, it was 8.5 but now it has touched 7.7. We did a serum ferritin test and her level was 50 (normal) which I guess means no iron deficiency. She is a beta thalassemia ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi,Welcome to minor is hemoglobinopathy and so the hemoglobin level can never be above 12 in such a patient. In pregnancy, plasma is increased and so hemodilution can lead to more fall in hemoglobin levels in CBC. Orofer XT like an Iron tablet can be prescribed for such cases...  Read Full »

My friend is a 20-year-old female and is a beta-thalassemia minor carrier with hemoglobin of 12.6 g/dl. Kindly help.

Query: Hello doctor,My friend is a 20-year-old female. She is a beta-thalassemia minor carrier and her hemoglobin is 12.6 g/dl. What does her report suggest? Kindly help.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to Based on the provided range I cannot comment regarding the possibility of thalassemia minor. I need to know the MCV, and RBC count as well to comment further. So kindly attach your full CBC (complete blood count) report so that I can give more detailed comments. I ho...  Read Full »

I have thalassemia minor. How to increase hemoglobin and decrease ferritin levels?

Query: Hi doctor, I am a 76 year old male, who is 170 cm tall and weigh 68 kg. Presently I have anemia, and my hemoglobin is 9.6 g/dL. I also have high serum ferritin level of 1900 ng/mL. I have this problem for some time. Many years ago, I was diagnosed with thalassemia minor. I was feeling tired, and I h...  Read Full »

Dr. Settipalli Saravan Pramod

Answer: Hi, Welcome to I have seen all your reports (attachment removed to protect patient identity). Thalassemia is an inherited blood disorder characterized by abnormal hemoglobin production. I do not have to explain you much about thalassemia as your doctor might have told you the details...  Read Full »

Is it too risky for me to marry someone with sickle cell trait if I have beta thalassemia trait?

Query: Hi doctor, I have beta thalassemia plus trait (AT+) and want to marry a man with sickle trait (AS). Please see the attached file of my beta thalassemia DNA genetics. Please give me the possibilities of our baby. I know there is a 25 % chance that the baby might have sickle beta plus¬†thalassemia (ST...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I have seen the reports (attachment removed to protect patient identity). Thalassemia and sickle cell anemia are autosomal recessive disorders. In your case, the child can be thalassemia sickle cell carrier (heterozygous). The presentation will be mild to moderate...  Read Full »

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