Common "Beta Thalassemia" queries answered by top doctors | iCliniq

Beta Thalassemia

Beta thalassemia is a blood disorder where there is abnormal hemoglobin production. It is caused due to mutation in the hemoglobin beta gene. There are three types of beta-thalassemia. They are beta thalassemia minor, beta thalassemia intermedia, and beta thalassemia major. Depending on the type of beta-thalassemia, the symptoms can be minor or severe. The signs and symptoms are shortness of breath, pale skin, tiredness, increased heart rate, and yellowish discoloration of eyes and skin. Taking regular blood transfusions along with medications helps to manage it.

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Does the relationship DNA test get affected by beta-thalassemia minor?

Query: Hi doctor, I am beta thalassemia minor. If I go for a relationship DNA test with my son, will the DNA report be false due to this?  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: No, a relationship DNA test will not be affected. It is autosomal related. He may or may not be a carrier. A DNA test will look at multiple patterns. If you want, you can go for a DNA test. Being affected by thalassemia...  Read Full »

Is my friend's beta thalassemia screening test seem normal?

Query: Hello doctor,My cousin of 30 years old got tested for beta thalassemia screening test. He got the result as hemoglobin A2 is 2.8 %, hemoglobin F is 0.2 %, and hemoglobin C, D, and S are not detected. Is this normal or has any complications?Please guide.  Read Full »


Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The beta-thalassemia screening test appears to be normal. HbA2 levels (hemoglobin A2) are normally between 2 to 3.3% and HbF levels (fetal hemoglobin) are 0.1 to 1.2% for this age. Both are normal. The other hemoglobin typ...  Read Full »

I am 6 months pregnant with beta thalassemia. Can you help?

Query: Hello doctor, I am a 24 year old female. I am 6 months pregnant. My hemoglobin level is 8.3 g/dL and I have heterozygous state of beta thalassemia. My doctor has advised for blood transfusion. Please help.  Read Full »


Dr. Sameer Kumar

Answer: Hello, Welcome to iciniq.com. The beta thalassemia carrier state, which results from heterozygosity for beta thalassemia, is clinically asymptomatic and is defined by specific hematological features. Considering that you are 6 months pregnant and your hemoglobin is 8.3 g/dL indicates moderate anaem...  Read Full »

Is beta thalassemia trait a serious case?

Query: Hello doctor, Is beta thalassemia trait a serious case? Please help.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. We are elated to have you on board at icliniq. Let me explain to you about the beta thalassemia trait. It is good that you are aware of using online health portals. Beta thalassemia trait is a heterozygous condition, and the patient can live a normal life. If nutrition...  Read Full »

I have beta thalassemia trait. Please suggest.

Query: Hi doctor, I have beta thalassemia plus trait (AT+) and want to marry a man with sickle trait (AS). Please see the attached file of my beta thalassemia DNA genetics. Please give me the possibilities of our baby. I know there is a 25 % chance that the baby might have sickle beta plus thalassemia (ST+...  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I have seen the reports (attachment removed to protect patient identity). Thalassemia and sickle cell anemia are autosomal recessive disorders. In your case, the child can be thalassemia sickle cell carrier (heterozygous). The presentation will be mild to mode...  Read Full »

I am a carrier of HbE beta-thalassemia. Please suggest.

Query: Hello doctor, Recently, I found out that I am a carrier of HbE beta-thalassemia. The problem is that my fiance is also a carrier and he is carrying the HbE trait. We do not want to separate. If you can give us your valuable advice, then it will be a great pleasure for us.  Read Full »


Dr. Veerendra Channabasappa Patil

Answer: Hi, Welcome to icliniq.com. From the information you provided, it seems that you have HbE beta thalassemia trait and your fiance has only Hb E trait. If so, then the chance of having a child with severe thalassemia is less. But, if you both have the same Hb E beta thalassemia trait, then there is...  Read Full »

Kindly guide me based on the blood electrophoresis report.

Query: Hello doctor, My younger brother's blood electrophoresis report is HbA 61.5, HbS 34.5, and HbF 3.6. So kindly tell me the condition of the patient and precautions to be taken.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Your attached report (attachment removed to protect patient identity) is suggestive of sickle cell plus beta thalassemia combination case. It can be sickle cell trait as well. For further confirmation, a molecular study can be done. As it is a homozygous condition, t...  Read Full »

What is the recommended diet for beta major thalassemia?

Query: Hi doctor,My daughter, who is 2.5 years old, is suffering from beta major thalassemia. From her three months of age, blood has been transfused either once in 30 or 45 days after checking the blood level. I would request you to kindly advise a good and healthy food diet. Is there any important daily ...  Read Full »


Dr. Prakash. H. M.

Answer: Hi,Welcome to icliniq.com.Based on your query, my opinion is as follows:Thalassemia is a disease due to reduced globin production in the hemoglobin part of RBC (red blood cells). It is not due to nutritional deficiency, but due to inherited mutation abnormalities.Yes, nutrition requires improvement....  Read Full »

Can sickle cell anemia and beta thalassemia occur together?

Query: Hi doctor, My friend is 26 years old. He has sickle cell anemia and thalassemia together. His recent spleen health was good and the proportion of blood and iron was moderate. He does not need to increase the blood. Is it rare to see these two together? What is the average life expectancy of these p...  Read Full »


Dr. Veerendra Channabasappa Patil

Answer: Hello, Welcome to icliniq.com. As per your description, your friend seems to be having sickle beta-thalassemia. It is common to see both these diseases together in communities where both diseases are prevailing. Actually, the severity of sickle cell disease comes down by the elevation of the Hb...  Read Full »

Can couple with same blood group give birth to healthy child?

Query: Hello doctor, My brother is worried about his marriage because of the same blood group. Both are having a B-positive blood group. Is there any problem after marriage for getting a healthy baby? Please explain it to me so that I can talk to him.  Read Full »


Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. Same blood group people can marry and can produce a normal child. There is two common universal blood group system that is ABO and Rh. If they both are relative then genetic counselling is needed. As far as same blood group is concerned, do not worry about that. If y...  Read Full »

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