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Q. What is meant by non-specific inflammatory lesion?

Answered by
Dr. Sadaf Mustafa
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Aug 19, 2017

Hi doctor,

I had excision biopsy for a lump in the left leg. The result shows the features of non-specific inflammatory lesion. What does it mean?

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Hello,

Welcome to icliniq.com.

  • Inflammation means your body's response to a self or foreign allergen or antigen.
  • The allergens are usually proteins either self or foreign. It includes bacterial or viral protein or your own cell protein which is now recognized as foreign by your immune system.
  • This is the process that leads to the activation of your body's immune process to combat infections and are also involved in autoimmune diseases.
  • Non-specific means that the agent responsible for the inflammation cannot be determined yet. This is either due to inadequate sample size or by the inability of the test performed to identify the cause.
  • Now coming back to the various reasons it may be an infection such as cellulitis or healing ulcer, erythema nodosum, post-traumatic healing, psoriasis, dermatitis of any kind or lupus.
  • We have to put the entire clinical picture to have a better diagnosis. In some situation biopsy alone might not be helpful.

For further information consult an internal medicine physician online --> https://www.icliniq.com/ask-a-doctor-online/internal-medicine-physician


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