HomeAnswersInternal MedicinebiopsyMy biopsy showed non-specific inflammation. Please help.

What is meant by non-specific inflammatory lesion?

What is meant by non-specific inflammatory lesion?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

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Published At August 19, 2017
Reviewed AtOctober 6, 2023

Patient's Query

Hi doctor,

I had excision biopsy for a lump in the left leg. The result shows the features of non-specific inflammatory lesion. What does it mean?

Answered by Dr. Sadaf Mustafa


Welcome to icliniq.com. Inflammation means your body's response to a self or foreign allergen or antigen. The allergens are usually proteins either self or foreign. It includes bacterial or viral protein or your own cell protein which is now recognized as foreign by your immune system. This is the process that leads to the activation of your body's immune process to combat infections and are also involved in autoimmune diseases. Non-specific means that the agent responsible for the inflammation cannot be determined yet. This is either due to inadequate sample size or by the inability of the test performed to identify the cause. Now coming back to the various reasons it may be an infection such as cellulitis or healing ulcer, erythema nodosum, post-traumatic healing, psoriasis, dermatitis of any kind or lupus. We have to put the entire clinical picture to have a better diagnosis. In some situation biopsy alone might not be helpful.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sadaf Mustafa
Dr. Sadaf Mustafa

Internal Medicine

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