Can the interaction between Lisinopril and Hydroxyzine lower my blood pressure?

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I understand your concern. Lisinopril and Hydroxyzine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment. Avoid driving or operating hazardous machinery until you know how the medications affect you and use caution when getting up from a sitting or lying position. What dose of Lisinopril do you take?

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Lisinopril is always started at a low dose and preferably at night before going to bed because Lisinopril causes lower blood pressure. During 1st few days, take Lisinopril and Hydroxyzine for 10 mg or 12.5 mg. Hydroxyzine is a diuretic that also lowers blood pressure. The side effect is postural hypotension, which means lowering blood pressure when standing from a lying position. Hydroxyzine and Lisinopril both have additive effects. So due to all this, your blood pressure dropped. Depending upon your blood pressure level, take Lisinopril 5 mg at night. If it does not normalize blood pressure in a week, the dose can be increased to 10 mg. If this also does not normalize blood pressure, then take Lisinopril 10 mg and Hydroxyzine 12.5 mg. So in this way dose should be gradually escalated. I practice this in most patients to keep them on the lowest anti-hypertensive amounts and save them from side effects. Thank you.