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How to treat my mom's satge 2B breast cancer at 75?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My mother is 75 years old, and she recently had a modified radical mastectomy for stage 2B invasive carcinoma (tumor size is 3x3, and two nodes of 19 dissected and had metastasis). Her biopsy results say that it is NHS-grade 3, and positive lymph vascular and perineural invasion is seen. The skin, areola, and nipple are free of tumors. It is a p2t2N1a and DCIS-intermediate. The tumor is hormone-positive with both estrogen and progesterone. HER2 is negative.

She is a cardiac patient having atrial fibrillation and hypertension.

Can you please advise treatment options considering her age?

Thank you.

Answered by Dr. Dinesh Kumar

Education:

MBBS

Professional Bio:

Dr. Dinesh Kumar is a Surgical Oncologist and a Gastroenterologist with 14 years of clinical experience. He has a keen interest in diagnosing and staging oncology cases. The ideal sequence of all treatment modalities is vital in diagnosing and treating cancer patients. He is interested in treating GI cancers, Head and Neck Cancers, Breast cancer, and Urological Cancers. Currently, he is practicing in Delhi.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Considering her age and the relatively good profile of breast cancer she had, I would suggest that we may avoid chemotherapy. Instead, she may receive radiotherapy and oral hormonal therapy (Letrozole).

Thanks and regards.

Patient's Query

Hi doctor,

Thanks for your response.

May I know the other oral hormonal drugs and their side effects?

Thank you.

Answered by Dr. Dinesh Kumar

Education:

MBBS

Professional Bio:

Dr. Dinesh Kumar is a Surgical Oncologist and a Gastroenterologist with 14 years of clinical experience. He has a keen interest in diagnosing and staging oncology cases. The ideal sequence of all treatment modalities is vital in diagnosing and treating cancer patients. He is interested in treating GI cancers, Head and Neck Cancers, Breast cancer, and Urological Cancers. Currently, he is practicing in Delhi.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

Letrozole is the safest drug for her. It may cause some bone aches, and she has to be on long-term calcium supplementation. There are a lot many other drugs also (from the same class of Letrozole, as well as from different classes). These are generally reserved for advanced diseases and they are Tamoxifen, Fulvestrant, and Anastrozole.

Thanks and regards.

Medically reviewed by Dr. Chithranjali Ravichandran
Published At April 30, 2022
Reviewed At October 24, 2025

Education:

MBBS

Professional Bio:

Dr. Dinesh Kumar is a Surgical Oncologist and a Gastroenterologist with 14 years of clinical experience. He has a keen interest in diagnosing and staging oncology cases. The ideal sequence of all treatment modalities is vital in diagnosing and treating cancer patients. He is interested in treating GI cancers, Head and Neck Cancers, Breast cancer, and Urological Cancers. Currently, he is practicing in Delhi.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Chithranjali is a passionate and skilled Dentist specializing in preventive care, restorative treatments, cosmetic dentistry, and oral health education. She excels in managing dental conditions with precision and compassion, ensuring patient comfort and positive outcomes. Committed to promoting long-term oral wellness, Dr. Chithranjali combines advanced dental techniques with personalized care, empowering patients to maintain healthy smiles and achieve optimal overall dental health.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Dinesh Kumar is a Surgical Oncologist and a Gastroenterologist with 14 years of clinical experience. He has a keen interest in diagnosing and staging oncology cases. The ideal sequence of all treatment modalities is vital in diagnosing and treating cancer patients. He is interested in treating GI cancers, Head and Neck Cancers, Breast cancer, and Urological Cancers. Currently, he is practicing in Delhi.

This doctor is not available for online consultations on the platform anymore.

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