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Is radiation or chemo recommended for breast cancer care?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

Can you please give me a second opinion on breast cancer treatment?

Hi,

Welcome to icliniq.com

According to your report (attachment removed to protect the patient's identity), post-mastectomy status is as follows:

  1. She is a 36-year-old female with two tumors in the resected breast in 11 o' clock and 1 o' clock position, which are more than 0.5-inch in size and also has the same side axillary lymph node of 19 mm with Ene+ (extranodal extension), ER/PR (estrogen receptor/progesterone receptor) ++, HER2 (human epidermal growth factor receptor) -- status and luminal A type cancer.
  2. The Prosigna test recurrence score is six percent.
  3. Node-negative cancers are classified as low (0 to 40), intermediate (41 to 60), or high (61 to 100) risk, and node-positive cancers are classified as low (0 to 40) or high (41 to 100) risk.
  4. She falls into the node-positive group; therefore, the risk of six percent mentioned in your report is considered low.

I would suggest the following treatment plan:

  1. Endocrine therapy alone for five years with tablet Tamoxifen + Leuprolide acetate.
  2. We can spare chemotherapy.

I hope this helps.

Thank you.

Patient's Query

Hi doctor,

Thank you for the response.

We consulted with the local doctors, and they are advising us to undergo radiation therapy. Kindly tell me if it is required, as the patient has already undergone total axillary node dissection. Can you tell me why doctors are still suggesting radiation, and also if we can take high-dose vitamin C intravenously during radiation therapy?

Please help.

Hello,

Welcome back to icliniq.com.

I understand your concern.

As we are skipping chemotherapy and also because it is a multicentric tumor (two tumors are resected at 1 o' and 11 o'clock positions), radiation therapy is required.

We have two options: either go for chemotherapy and avoid radiation, or go for radiation therapy along with endocrine therapy.

I would suggest that you go for the second option because it is easier and better. And also as far as you are concerned, the Prosigna test suggests no many benefits for chemotherapy.

I hope you find this helpful.

Thank you.

Medically reviewed byiCliniq medical review team

Published At May 4, 2021
Reviewed AtDecember 10, 2025

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