Is a biopsy necessary for managing a PI-RADS 3 lesion?

Question

Hello doctor,

My latest PSA is 4.8 ng/mL, up from 2.9 last year. The MRI shows a PI-RADS 3 lesion, and my urologist wants to perform a targeted biopsy. I am hesitant because my brother had complications from his biopsy last year. What are the risks of waiting versus proceeding with the biopsy? Could we monitor with another MRI in a few months?

Kindly guide.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and understood it.

I understand your fears, but the best way to know if it is cancer is through a biopsy. The biopsy will help determine if it is cancerous or not, and also show the stage and the need for urgent treatment.

An MRI (magnetic resonance imaging) is not a bad option, but it is not as sensitive as a biopsy. Every procedure has potential complications, but there are measures in place to treat such complications. Please do not let fear cause you to make the wrong decision now.

Also, what is your brother’s condition now?

I hope this has helped you.

Kindly follow up if you have more doubts.

Thank you.