Dr. Abdul Aziz Khan
Medical oncology
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
Answered by
Medically reviewed by
Patient's Query
Hi doctor,
My niece's boyfriend was diagnosed with CML three months back with BCR-ABL positive. He is now stable and is taking Imatinib 400 mg daily. Earlier she was considering engaging with the boy for marriage. Now she wants to know the risk factors she has to face if she goes ahead with the wedding. I have attached the reports. Kindly help.
Hi,
Welcome to icliniq.com.
I had gone through the reports attached (attachments removed to protect the patient's identity). CML (chronic myelogenous leukemia) is a chronic disease that is compatible for long survival with current targeted therapy, like tablet Imatinib, but it is difficult to say for how long. It usually transforms into acute leukemia, and the patient dies because of it.
Patient's Query
Hi doctor,
Thank you for the reply.
With existing blasts of 7 % as per bone marrow biopsy, what are the chances of progression of the disease?
Hi,
Welcome back to icliniq.com.
For understanding remission, BCR-ABL gene translocation needs to be tested. If positive, Imatinib will be changed to another drug. I suggest reviewing his CBC (complete blood count) with peripheral blood film and BCR-ABL reports.
Was this conversation helpful?
Same symptoms don't mean you have the same problem. Consult a doctor now!
Medical oncology
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.
This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy
