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Is Coenzyme Q10 supplement safe for breastfeeding mothers?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 38-year-old mother currently breastfeeding my 18-month-old son. I plan to begin trying to conceive (TTC) again, as I am mindful of my age and its potential impact on fertility, particularly concerning egg quality.

To support this, I am considering supplements such as vitamin D3, omega-3 fish oil, and Coenzyme Q10 (CoQ10). However, I am aware that research on the safety of CoQ10 supplementation during breastfeeding is limited. Given that I breastfeed my son two to three times per day, I would appreciate your guidance on whether it is advisable to start CoQ10 supplementation at this time. Please help.

Thank you.

Answered by Dr. Siphesihle Sokhulu

Education:

MBBS

Professional Bio:

Dr Siphesihle Sokhulu is a General Practitioner who has completed MBBS from the University of KwaZulu Natal in 2021. He has a clinical experience of four years. He treats his patients with atmost kindess and care. He is currently working in VitalCare Medics Inc in South Africa. 

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I understand your concern.

Thank you for reaching out with your thoughtful question. It is commendable that you are proactively planning for your second pregnancy and considering factors like age-related fertility and supplement safety during breastfeeding. Let us address your concerns step by step:

Trying to conceive (TTC) at 38 while breastfeeding:

It is encouraging that your son is now 18 months old and breastfeeding has reduced to two to three times daily. This decrease often leads to the natural resumption of ovulation. While fertility can decline gradually after 35 due to changes in egg quality and ovarian reserve, many women in their late 30s successfully conceive, especially when menstrual cycles are regular and ovulation has resumed.

Safety of CoQ10 during breastfeeding:

Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant commonly used to support egg quality, particularly in women over 35. However, data on its safety during breastfeeding are limited. Some sources suggest that CoQ10 is compatible with breastfeeding and poses a very low risk to infants. Nonetheless, due to the lack of comprehensive studies, it is advisable to consult your healthcare provider before starting CoQ10 supplementation. If you choose to proceed, consider:

  1. Starting with a low dose like 100 mg per day.

  2. Monitor your baby for any unusual changes, although adverse effects are rare.

  3. Discuss with a lactation-friendly healthcare provider to ensure safety.

Other safe supplements to support fertility:

You have made excellent choices when considering supportive nutrients. Here is a breakdown:

  1. Vitamin D3: Safe during breastfeeding and important for both maternal and fetal health. A daily intake of 1,000–2,000 IU is generally recommended, but it is best to check your levels and consult your doctor for personalized advice.

  2. Omega-3 fish oil (DHA/EPA): Beneficial and safe, opt for molecularly distilled fish oil to ensure it is free of mercury and other toxins.

  3. Prenatal vitamins or folic acid (400 to 800 mcg): Essential when preparing to conceive the folic acid is safe during breastfeeding and helps prevent neural tube defects in the developing fetus.

  4. Inositol (especially Myo-inositol): May support ovulatory function and insulin sensitivity, particularly in women with irregular cycles.

Fertility tips specific to your situation:

  1. Monitoring ovulation: Since you are still breastfeeding occasionally, watch for signs of returning ovulation, such as changes in cervical mucus, basal body temperature shifts, or results from ovulation predictor kits.

  2. Maintaining a healthy weight: If your body mass index(BMI) is slightly elevated, even modest weight loss (five to 10 percent) can positively impact ovulation and fertility.

  3. Consulting a specialist: If conception does not occur after six months of trying, especially considering age-related factors, it may be beneficial to consult a fertility specialist

In the meantime, please follow these steps:

  1. You can begin trying to conceive as planned. Breastfeeding two to three times daily is unlikely to significantly affect fertility at this stage.

  2. CoQ10 may be used cautiously during breastfeeding, particularly at lower doses, but consult your healthcare provider first.

  3. Continue or initiate supplementation with vitamin D3, omega-3s, folic acid, and a prenatal multivitamin.

  4. Monitor for signs of ovulation and consider a preconception check-up for personalized guidance.

Please feel free to reach out if you need assistance interpreting ovulation tests, selecting appropriate supplements, or planning your conception timeline.

Wishing you all the best.

I hope this helps.

Thank you.

Medically reviewed by iCliniq medical review team
Published At August 19, 2025
Reviewed At August 21, 2025

Education:

MBBS

Professional Bio:

Dr Siphesihle Sokhulu is a General Practitioner who has completed MBBS from the University of KwaZulu Natal in 2021. He has a clinical experience of four years. He treats his patients with atmost kindess and care. He is currently working in VitalCare Medics Inc in South Africa. 

This doctor is not available for online consultations on the platform anymore.

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CoQ10 Supplementation Safety During Breastfeeding and Fertility Decision Helper

Considering CoQ10 for fertility while breastfeeding?

Answer five quick questions to understand if CoQ10 supplementation is advisable for you right now, considering your breastfeeding status and fertility plans.

This tool provides educational information only and does not diagnose, treat, or replace professional medical advice. Consult a qualified healthcare professional for personalized medical guidance. Medications should be taken after consulting a physician. The dosages will be prescribed by the physician. Do not alter, start, or stop medications without consulting a healthcare professional.

Education:

MBBS

Professional Bio:

Dr Siphesihle Sokhulu is a General Practitioner who has completed MBBS from the University of KwaZulu Natal in 2021. He has a clinical experience of four years. He treats his patients with atmost kindess and care. He is currently working in VitalCare Medics Inc in South Africa. 

This doctor is not available for online consultations on the platform anymore.

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