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Is colonoscopy needed for ulcerative colitis?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have ulcerative colitis, and I am taking Humira 40 mg every other week. I did a colonoscopy, and there was mild inflammation. However, recently, I did a calprotectin test, and the result was 1000 mg. I retook the test after a month, and the result was 1120 mg. My CRP is 0.4 mg/L. My gastroenterologist does not think I should be worried and thinks it might be due to food poisoning two months ago. I want a second opinion. Do I need rescue therapy? Should I increase the dosage for Humira? Do I need a colonoscopy?

Thanks.
Answered by Dr. Sanya Dhingra

Education:

MBBS

Professional Bio:

Dr. Sanya Dhingra is a dedicated General Practitioner with extensive years of clinical experience. She is passionate about working closely with patients, providing comprehensive care for a wide range of health conditions. Dr. Dhingra focuses on accurate diagnosis, effective treatment, and preventive healthcare to promote overall well-being. Her patient-centered approach ensures compassionate, holistic, and quality medical care for individuals across all age groups.

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Hello,

Welcome to icliniq.com.

I understand your concern.

Your calprotectin levels are high. Generally, this means that you have IBS (inflammatory bowel syndrome) (which is, of course, diagnosed already). Mostly, it is high in cases of IBS, some bacterial infections of the intestine, cancer of the intestine, and the excessive use of anti-inflammatory medicines. You can get a colonoscopy done if you have worsening symptoms; otherwise, it is not needed. Kindly share all the lab reports done. Also, let me know if you have a history of intestinal cancer in your family.

I hope this information will help you.

Thanks.

Medically reviewed by iCliniq medical review team
Published At June 19, 2025
Reviewed At June 25, 2025

Education:

MBBS

Professional Bio:

Dr. Sanya Dhingra is a dedicated General Practitioner with extensive years of clinical experience. She is passionate about working closely with patients, providing comprehensive care for a wide range of health conditions. Dr. Dhingra focuses on accurate diagnosis, effective treatment, and preventive healthcare to promote overall well-being. Her patient-centered approach ensures compassionate, holistic, and quality medical care for individuals across all age groups.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sanya Dhingra
Dr. Sanya Dhingra

General Practitioner

Education:

MBBS

Professional Bio:

Dr. Sanya Dhingra is a dedicated General Practitioner with extensive years of clinical experience. She is passionate about working closely with patients, providing comprehensive care for a wide range of health conditions. Dr. Dhingra focuses on accurate diagnosis, effective treatment, and preventive healthcare to promote overall well-being. Her patient-centered approach ensures compassionate, holistic, and quality medical care for individuals across all age groups.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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